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Physio
Exam 3
35
Physiology
Graduate
10/24/2008

Additional Physiology Flashcards

 


 

Cards

Term
alpha 1 adrenergic
Definition
Epi or NorE
Gq
Term
alpha 2 adrenergic
Definition
Epi or NorE
Gi
Term
beta 1 adrenergic
Definition
Epi or NorE
Gs
Term
beta 2 adrenergic
Definition
Epi or NorE
Gs
Term
beta 3 adrenergic
Definition
Epi or NorE
Gs
Term
M2 muscarinic cholinergic
(M4)
Definition
ACh
Gi
Term
M3 muscarinic cholinergic
(M1,M5)
Definition
ACh
Gq
Term
Gs
Definition
act adenylate cyclase, open cell membrane Ca++ channels
Term
Gi
Definition
Inhibit adenylate cyclase, open cell membrane K+ channels
Term
Gq
Definition
Activate phospholipase C-beta
Term
Muscarinic
Definition
ACh
Muscarine (agonist)
Atropine (antagonist)
Term
Nicotinic
Sub-type N muscle
Definition
ACh
Nicotine (agonist)
Curare (antagonist)
Term
Leuprolide
Definition

Prostitutes dying wish was to take her boobies to a leuau to stop guys w/no balls from making rounds, to let her gonads go!

Irrev prostate cancer, gynecomastia, Leuprolide, anti-androgen, bilateral orchiectomy and LHRH analog, stop circulating, and release of GNRH. 

Term
Flutamide
Definition

Flutes buy guys time when making rounds.

Anti-andro, decrease circulating to buy time.

Term
Anastrozole
Definition

A nasty smell.

Aromatase inhib.

Term

Exemestane

Fulvestrant

Definition

Exams smell bad to women wearing full vests.

Aromatase inhib, est receptor block b/c have no estradiol to bind to receptors. (Fulvest is also anti-est)

Term
Tamoxifen
Definition

Hammocks are bad for post-menopausal competitive depressed women.

Anti-est, compete for est receptor, drives Liver metabolism (CYP2D6) to active, bad for x-depression drugs (Paxl, prazac) b/c they need the enzymes too.

Term
5-FU
Definition

Loose temper, loose hair and yell "FU!!!"

Less TMP via inhib thymidylate synthetase.  Hair loss like cyclophos.

Term
Corticoids: Prednisone
Definition

Flute players on extreme steroids lay in hammocks @ leuau wearing nasty vests.

Flutamide, Exemestane, Corticoids, Tamoxifen, Leuprolide, Anastrozole, Fulvestrant.

Term
Cisplatin
Definition

Bloody alky peed on a solid plate S/F chocolate chip cookies.

IV in, like alkylating agents, renal tox, solid tumors, platinum containing, manitol diuresis and hydration, like chocolate chip cookie discovery (from lab to XB).

Term
Folinic Acid
Definition

Foley catheters rescue patients.

In periph, give Folinic acid and can make tetra w/out dyhydro enzyme.

Term
Doxorubicin (Adriamycin)
Definition

Bald Adrian stalks Deena, latches on and stops her from running, gives her a heart attack, and makes her keep a low profile.  Too bad because its common to see her running as shes a solid runner.

Hair loss, Adriamycin, binds DNA to stop RNA, cardio tox, keeps blood levesl below a certain amount. Common chemo, solid tumors.

Term
Mitomycin
Definition

Meet my solid Alky.

Alkylating, solid tumors.

Term
Natural Ab's
Definition

Adrian blew my acting gig, sad cuz I'm such a mighty natural.

Adriamycin (doxorubicin), Bleomycin, Actinomycin D, Mitomycin, Natural Ab's.

Term
Bleomycin
Definition

Blowing solidly wont break Deena.

Pulmonary fibrosis, solid tumors, DNA breaks.

Term
Actinomycin D
Definition

Runners naturally act like don't have stress fractures, and can run when very sick.

RNA synth, non-cycle active, BM supp, Very toxic, immuno sup (lots).

Term
Methotrexate
Definition

Kids on meth sniff watery glue.

DON'T GIVE TO RENAL ISSUES!!!!  sniff to bring into cell, inhib dihydrofolate reductase (can't become tetra), conj to Glu to trap inside cells.

Term
Vins
Definition

I met Vin, he blasted my solid cycle and moved on to  cute brainy Christine because shes a natural.

Metaphase stop, Vins's, Blast: myelosupp, solid tumors, cycle active, cristine: CNS, acute leuk.  Natual Product

Term
Paclitaxel (Taxol)
Definition

Solid tax on all natural bike tubes.

Solid tumor, taxol, natural product, cycle active microtubles less pliable so can't pull apart.

Term
Gemcitabine
Definition

Denas wedding ring altered her temporary (non-active) status.

DNA synth, GEM, alteres temp activity, non-cycle active, solid tumor.

Term
Tegafur
Definition

Keep yelling FU! at pros who use tees or stay in water!!

Keeps 5-FU high b/c competes for dyhydropyrimidine dehydrogenase.  Prodrug metabolized to flurouracil.

 

Term
6-Mercaptopurine
Definition

Captain has pure IMPotence.

Blocks IMP form, and other steps to purine synthesis.

Thioguanine does same for GMP.  (alter structure and function) w/both = complementary inhib.

6-mer blocks IMP and it's change to AMP and GMP = sequential inhib.

Term
Busulfan
Definition

Booze for my alkys.

Myelosupp, alkylating agent.

Term
Alkylating agents
Definition

Pho long horn rams @ BU are fat, ride bus, b/c got BUI for being non-functional.

Cyclophosp (hair loss, rapid, metabolic activation and normal liver), Chlorambucil (least toxic, for chronic), BCNU (IV, Lipid, CNS), Busulfate (myelosup), non-cycle active, modify pre-formed (change structure and function), alkylating agents.

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