Term
| Control of Blood Flow and Pressure: |
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Definition
Pressure-Flow Autoregulation
Myogenic Regulation
Metabolic Regulation
Flow mediated vasodilation
Autonomic Regulation
Reflex Regulation |
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Term
| Regional resistance is calibrated, so flow meets the metabolic and functional requirements of each tissue. |
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Definition
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Term
Pressure-flow autoregulation keeps flow nearly constant despite large changes in pressure. Tissue is adequately perfused but not over perfused. Microcirculation is protected from high arterial pressure. Pressure-flow autoregulation fails at very low and high pressures.
Change in pressure causes vascular smooth muscle to contract or relax (myogenic regulation).
Change in flow due to change in pressure alters regional concentration of vasoactive metabolites (metabolic regulation). |
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Definition
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Term
| Myogenic Regulation – Increasing Transmural Pressure Stimulates Vascular Smooth Muscle to Contract and the Arteriole Diameter Decreases |
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Definition
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Term
| so with myogenic regulation, when the the pressure increases due to muscle contraction, the vessel constricts in order to keep blood flow the same. |
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Definition
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Term
| Local Metabolic Control Mechanisms Match Blood Flow To Tissue Demand For Oxygen and Substrates, so an increae in oxygen consumption will increase flow |
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Definition
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Term
| Reactive hyperemia reacts to a brief arterial obstruction. Height of flow and duration increases as duration of obtruction continues |
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Definition
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Term
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Definition
K+ATP channels
ATP - ADP
AMP
O2
CO2
K+
H + (lactic acid) |
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Term
| during hypoxia, vessels ___ due to presence of ___ ions. |
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Definition
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Term
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Definition
| Sudden changes in systemic arterial blood pressure initiate a reflex that evokes inverse changes in cardiac rate and contractility and in vascular resistance. Pressure is sensed by baroreceptors in the aortic arch and carotid sinuses. Information is processed in the nucleus of the tractus solitarius in the medulla, and sympathetic and parasympathetic tone are modulated. |
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Term
| sympathetic tone modulates: |
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Definition
Heart Rate
Myocardial Contractility
Vascular Resistance
Vascular Compliance |
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Term
| baroreceptor reflex is an example of |
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Definition
| negative feed back system |
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Term
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Definition
Response to O2, CO2, H+
Major effect on respiration
Excites vagal center to slow heart rate
Activation of sympathetic nervous system to constrict resistance and capacitance vessels |
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Term
| LOW OXYGEN, HIGH CO2, HIGH H+, LOW PH STIMULATES THESE> CHEMORECEPTORS EXCITED> INCREASED RESPIRATION>AND CHEMORECEPTORS EXCITES VAGAL TO SLOW HEART RATE> SYMP ALSO ACTIVATED TO CONSTRICTE RESISTANCE AND CAPACITANCE VESSELS. |
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Definition
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