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Phy Sci 5 - Midterm - Topic 2
Lifestyle & Chronic Disease
17
Physiology
Undergraduate 1
04/28/2009

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Term
Lifestyle: pre 1900's
Definition
people spent more time preparing meals, gathering & growing the ingredients, & performing physical labor. They walked, food was not processed, and they generally moved more.
Term
Lifestyle: 1900 - present
Definition
childhood obesity has quadrupled (more than 33%) as a result of video games, computer, and tv mixed with a "Western" diet. Since human genetics have not changed in the past 100 years, the rise in incidence of chronic diseases is due solely to lifestyle changes.
Term
Chronic Diseases
Definition
or degenerative diseases; ones that develop over the course of a whole lifetime an whose obvious symptoms might appear without warning. The result of interaction between our genes and the environment, they can change the function of our cells.
Term
Inherited Genetic Mutation
Definition
cause of the chronic diseases NOT related to lifestyle.
Term
Susceptibility Genes a.k.a. Gene Polymorphisms
Definition
cause one to become predisposed to developing a disease. Increase the risk of developing a disease when its expression changes in a manner unconducive to its normal composition.
Term
Lifestyle Choices
Definition
determine whether disease traits are expressed and if one actually develops the disease.
Term
Gene Expression
Definition
process of producing proteins from the genetic code (DNA) in our cells.
Term
Transcription (gene expression)
Definition
when copies of a gene that is to be expressed are produced.
Term
Translation
Definition
when copies of genes are decoded and form proteins.
Term
Enzymes
Definition
biological catalysts that speed up chemical reactions in the body - analogy to water boiling.
Term
Cytoskeletal Proteins
Definition
support and organize cell components and control their movement i.e. a scaffolding for the cell and railroad tracks for its movement.
Term
Myosin & Actin
Definition
proteins that comprise muscle tissue and are involved in muscle contraction.
Term
Hormones
Definition
signaling molecules that help the body's cells communicate with each other i.e. insulin.
Term
Antibodies
Definition
proteins produced in the body in response to foreign substances i.e. the immune system.
Term
Receptors/Transporters
Definition
proteins embedded in the cell membrane and function as communicators between the outside and the inside of cells.
Term
Life Expectancy
Definition
an estimate of how long one will live on average. The age to which 50% of the population will survive. Has increased ~25 years with changes in causes of death.
Term
Lifespan
Definition
maximum time the population can survive; has remained at roughly 100 years since 1900 due to high incidence of chronic diseases.
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