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Phisio Psych final
Stress & Emotion, sleep, memory, lateralization, & mood disorders
138
Psychology
Undergraduate 3
11/12/2011

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Term
Functions of sleep
Definition
-Restoration of the brain and body
-energy conservation
-memory consolidation/learning
Term
Symptoms of moderate sleep deprivation
Definition
-Impaired concentration
-irritability
-tremors
-unpleasant mood
-decreased immune system function
Term
Symptoms of chronic sleep deprivation
Definition
-Obesity
-stress disorders
-immune system failure
-increased metabolic rate, appetite, and temperature
-decrease in overall brain activity
Term
Evolutionary Theory of Sleep
Definition
The function of sleep is to conserve energy by decreasing body temperature and muscle activity. (similar to the hibernation of animals)
Term
How long is optimal sleep time?
Definition
8-10 hours
Term
Why should we sleep?
Definition
It enhances learning, memory, and performance on newly-learned tasks
Term
How does sleep enhance performance on a newly-learned task?
Definition
Increased brain activity occurs in the area of the brain activated by a newly-learned task
Term
Activation-synthesis hypothesis
Definition
dreams begin with spontaneous activity in pons --> Pons activates many parts of the cortex --> cortex synthesizes story from pattern of activation --> normal sensory info. can't compete with self generated stimulation, and "hallucinations" result
Term
Clinico-anatomical hypothesis
Definition
Dreams are similar to thinking, just under unusual circumstances: Dreams begin with arousing stimuli within the brain --> stimulation is combined with recent memories and current sensory stimulation
Term
endogenous
Definition
Generated from within
Term
endogenous circannual rhythms
Definition
internal mechanisms that operate on an annual cycle (i.e. bird migratory patterns)
Term
Endogenous Circadian rhythms
Definition
internal mechanisms that operate on an approximate 24-hour cycle
Term
Examples of circadian rhythms
Definition
-sleep/wake cycle
-frequency of eating & drinking
-body temperature
-secretion of hormones
-volume of urination
-sensitivity to drugs
Term
Free-Running rhythm
Definition
rhythm that occurs when no stimuli reset or alter it
Term
Biological cues
Definition
sunrise = light + increasing temperature
Sunset = dark + decreasing temperature
Term
purpose of circadian rhythm
Definition
to keep our internal working in phase with the outside world
--->light is critical for periodically resetting it
Term
Zeitgeber
Definition
term used to describe any stimulus that resets circadian rhythms (exercise, noise, meals, temp., etc.)
Term
Jet lag
Definition
disruption of circadian rhythm due to crossing time zones
Term
Suprachiasmatic Nucleus (SCN)
Definition
-Part of the hypotalamus that is the main control center of circadian rhythms for sleep & temperature
-it's genetically controlled & independently generates circadian rhythm
Term
Retinohypothalamic path
Definition
how light reaches and resets the SCN
Term
Pineal gland
Definition
endocrine gland located posterior to the thalamus
Term
SCN regulates what gland?
Definition
Pineal gland
Term
functions of the pineal gland
Definition
secretes melatonin (hormone that increases sleepiness)
Term
How many stages of sleep are there?
Definition
Four Stages plus REM
Term
alpha waves
Definition
state of relaxation
Term
Stage 1 sleep
Definition
when sleep has just begun; brain activity begins to decline
Term
Stage 2 sleep
Definition
characterized by the presence of sleep spindles and k-complexes
Term
sleep spindles
Definition
12- to 14-Hz waves during a burst that lasts at least half a second
Term
K-complexes
Definition
a sharp high-amplitude negative wave followed by a smaller, slower positive wave
Term
Stages 3&4 sleep
Definition
constitute slow-wave sleep
-slowing of heart rate, breathing rate, and brain activity
-highly synchronized neuronal activity
Term
REM sleep
Definition
characterized by rapid eye movements
-Paradoxical sleep because EEG waves resemble awake state
-strongly associated with dreaming
-Brain actively paralyzes you in this time
Term
Duration of full sleep cycle
Definition
90 min
-sleep stages change as the night progresses: deep sleep stages (3&4) get shorter; REM sleep gets longer
Term
Sleep cycle
Definition
Stages 1, 2, 3, 4, 3, 2, REM
Term
Possible functions of REM
Definition
-Brain may discard useless connections
-learned motor skills may be consolidated
-oxygen may be delivered to corneas
Term
Insomnia
Definition
inability to fall asleep or stay asleep
Term
sleep apnea
Definition
periodic inability to breathe while sleeping
Term
causes of sleep apnea
Definition
obesity, growth in windpipe, weak lungs, deterioration of brain mechanisms that control breathing
Term
Causes of insomnia
Definition
noise, stress, pain medication, epilepsy, Parkinson's, depression, anxiety, etc.
Term
Narcolepsy
Definition
frequent periods of sleepiness
Term
symptoms of narcolepsy
Definition
-gradual or sudden attack of sleepiness
-cataplexy
-sleep paralysis
-hypnagogic hallucinations
Term
cataplexy
Definition
muscle weakness triggered by strong emotions
Term
hypnagogic hallucinations
Definition
dreamlike experiences the person has difficulty distinguishing from reality
Term
periodic limb movement disorder
Definition
repeated involuntary movement of the legs and arms while sleeping
Term
REM Behavior Disorder
Definition
acting out dreams
-mainly affects elderly men with brain diseases
-presumed cause: Damage to pons
Term
night terrors
Definition
experiences of intense anxiety from which a person awakens screaming in terror
Term
sleep talking
Definition
occurs in both REM and NREM sleep
Term
sleep walking
Definition
runs in families, mostly occurs in young children in stage 3 or 4 sleep
Term
An emotional state has 3 aspects
Definition
1. Cognition
2. Readiness for action
3. Feeling
Term
"Ready for action" aspect of emotion
Definition
Product of the autonomic nervous system
Term
James-Lange Theory
Definition
Autonomic arousal & skeletal actions occur before an emotion (not a lot of support for this, but certain body actions may slightly influence emotion)
Term
Cannon-Bard Theory
Definition
emotion occurs before autonomic arousal & skeletal actions
Term
Limbic system
Definition
forebrain areas surrounding the thalamus; traditionally regarded as critical for emotion
Term
amygdala
Definition
-part of the limbic system
-involved in many emotions and motivations
-processes fear, anger, and pleasure
Term
When you think "limbic system," think these parts of the brain
Definition
amygdala, frontal lobe, temporal lobe
Term
Do emotions tend to be localized in specific parts of the cortex?
Definition
Nope. A single emotion can increase activity in various parts of the brain
Term
What emotion does appear to be localized?
Definition
disgust in the insular cortex (primary taste cortex), but it can become activated even if the stimulation is NOT taste
Term
Behavioral Activating System (BAS)
Definition
the frontal and temporal areas of the left hemisphere
Term
Behavioral Inhibition System
Definition
frontal and temporal areas of the RIGHT hemisphere
-especially activated by unpleasant emotions
-damage causes problems identifying emotions of others
Term
Function of emotions
Definition
Help make decisions (especially moral decisions)
Term
Attack Behaviors
Definition
septum in limbic system (connection from frontal lobe to amygdala)
-causes inhibition in aggression (septal rage)
Term
What specific behaviors influence stress?
Definition
Diet, smoking, exercise, stressful experiences, etc.
Term
Hans Selye's definition of stress
Definition
the non-specific response of the body to any demand made upon it
Term
Symptoms of stress
Definition
muscle fatigue, teeth grinding, upset stomach, dizziness, irritability, anger, nervousness, crying, sleep impairments.
Term
How does prolonged stress affect the physical body?
Definition
When there's a prolonged increase of cortisol, it detracts from the synthesis of proteins in the immune system.
Term
distress
Definition
A physiological or psychological demand that is negative or damaging in nature
Term
eustress
Definition
positive or uplifting in nature
Term
General Adaptation Syndrome Stages
Definition
-Alarm Stage
-Resistance Stage
-Exhaustion Stage
Term
Alarm Stage of General Adaptation Syndrome
Definition
The body is activated to combat a stressor (fight or flight)
-if everything is ok, homeostasis occurs; if not, move to the next stage
Term
Resistance Stage of the general adaptation syndrome
Definition
The body is still trying to fight, and chronic stress begins
**can go into shock in this stage
-the body tries to adapt, but essentially runs out of fuel (heart palpitations, ulcers, etc.)
Term
Exhaustion Stage of the General Adaptation Syndrome
Definition
The body's used up all its fuel
--death can occur
Term
Stress activates 2 systems in the body
Definition
1. autonomic nervous system
2. HPA axis
Term
HPA axis
Definition
Hypothalamus Pituitary Adrenal Axis
--hypothalamus directly activates the sympathetic nervous system
--->immediate response: adrenal glands release adrenaline and noradrenaline (increases HR & BP)
--activates the limbic system and selective attention at the same time
Term
Other areas activated by the HPA axis:
Definition
pituitary gland, thyroid gland, and pancreas
Term
cytokines
Definition
cell-signaling protein molecules that produce symptoms of illness to force the body to rest
Term
How can stress be harmful to the hippocampus?
Definition
hippocampal neurons are sensitive to increased metabolic activity and are likely to sustain damage from toxins of overstimulation
Term
Classical Conditioning
Definition
When a condition stimulus is paired with an unconditioned stimulus and automacally results in an unconditioned response (Pavlov)
Term
Operant Conditioning
Definition
reinforcement or punishment strengthen or weaken a behavior
Term
Reinforcers
Definition
Events that increase the porbability that the response will occur
Term
Punishment
Definition
Events that decrease the probability that the response will occur
Term
To increase a desired behavior
Definition
-present positive reinforcement
-remove negative punishment
Term
To decrease an unwanted behavior
Definition
-present positive punishment
-remove negative reinforcement
Term
Equipotentiality
Definition
all parts of the cortex contribute equally to complex behaviors
Term
mass action
Definition
the cortex works as a whole, not as solitary isolated units
Term
Karl Lashley
Definition
searched for physical representations of what is learned in the brain (engrams) and gained 2 key principles: equilpotentiality and mass action
Term
learning occurs
Definition
in the cortex and some evidence supports the cerebellum (LIP)
Term
Hebb's two types of memory
Definition
Short-term memory
long-term memory
Term
Working memory
Definition
-prefrontal cortex (planning, attention, "executive" functioning)
-emphasis on temorary storage of info to actively attend to it & work on it for a period of time.
Term
Older people often have impairments in working memory because
Definition
-of assumed prefrontal cortex changes
-->declining activity of the prefrontal cortex is associated with decreasing memory
Term
Amnesia
Definition
loss of memory resulting from damage to the hippocampus
Term
Anterograde Amnesia
Definition
Loss of the ability to form new memory
Term
Retrograde amnesia
Definition
loss of memory events prior to the occurrence of the brain damage
Term
Explicit Memory
Definition
deliberate recall of information that one recognizes as a memory
Term
Implicit Memory
Definition
The influence of recent experience on behavior without realizing one is using memory
Term
Hippocampus and memory
Definition
1. Critical for declarative memory
2. Critical for spacial memory
3. Important for configural learning & binding
Term
configural learning
Definition
learning the features of things
Term
lateralization of function
Definition
refers to the idea that each hemisphere of the brain is specialized for different functions (division of labor)
Term
What are some crossover points between the two hemispheres of the brain?
Definition
Main: corpus callosum
-anterior commissure and hippocampal commissure (brief delay here; the smaller the commissure, the longer the delay)
Term
Which hemisphere is specialized for language?
Definition
Left (in MOST humans)
Term
Purpose of corpus callosum
Definition
to allow each hemisphere to receive information
Term
Optic chiasm
Definition
half of the axons of each eye cross to the opposite side of the brain.
Term
How does damage to the corpus callosum affect the brain?
Definition
it interferes with the exchange of information between hemispheres
Term
epilepsy
Definition
a condition characterized by repeated episodes of excessive synchronized neural activity mainly due to decreased release of the inhibitory neurotransmitter GABA
Term
Split-brained people
Definition
1.can use hands independently
2. Respond differently to stimuli presented to only one side of the body
Term
Big names in split-brained phenomena
Definition
Sperry & Gazzinga
-->found some crossover in smaller commissures
Term
Right hemisphere
Definition
generally better at perceiving emotions & spatial relationships
Term
damage to the right hemisphere causes
Definition
difficulty perceiving others' emotions, failure to understand sarcasm & a monotone voice
Term
Damage to the left hemisphere
Definition
increases ability to accurately judge emotion
Term
In general the left hemisphere focuses more on ___________ and the right hemisphere focuses more on _____________.
Definition
visual details
visual patterns
Term
planum temporale
Definition
area of the temporal cortex that is larger on the left side (usually)
-->related to language
Term
Evolution and physiology of language
Definition
1. human language is a complex form of communication
2. compared to other species, human language has high productivity
3. human language is probably a modification of behavior also found in other species
Term
How does the use of language by chimps differ from human language?
Definition
-Use of symbols lacks productivity
-Use of symbols is primarily used to request and not describe.
-Production of requests is better than understanding others’ requests.
Term
Productivity (in language)
Definition
the ability to produce new signals to represent new ideas
Term
What species of chimpanzees most closely resemble humans in language?
Definition
bonobos or pygmy chimps
Term
Why study nonhuman language ability?
Definition
-insights to how best to teach language to those who do not learn it easily
-indicates that language evolved from a precursor found in other species
Term
Williams Syndrome
Definition
characterized by mental retardation but skillful use of language.
Term
Major depression symptoms
Definition
-loss of pleasurable feelings
-feelings of worthlessness
-recurrent thoughts of death
-decreased concentration
-difficulty making decisions
-depressed mood
-basic bodily processes disrupted
Term
basic bodily functions that can be affected by major depression
Definition
-sleep
-appetite
-circadian disruptions
-weight loss/gain
-decreased motor activity
-loss of energy (anergia)
Term
Risk factors for major depression
Definition
-having a relative (esp. female) diagnosed before age 30
-early negative events
-decreased ability of brain to synthesize/reuptake serotonin in some
-stress?
Term
tricyclics
Definition
older drug therapy for depression
-->prevent pre-synaptic neurons from re-absorbing serotonin or catecholamines
Term
MAOI
Definition
Monoamaine oxidase Inhibiors
-->block monoamine oxidase
--->more neurotransmitters in the synapses longer
--->risks hypertension
Term
SSRI
Definition
Selective Serotonin Reuptake Inhibitors
-->block reuptake of serotonin after its release
Term
Atypical depression therapies
Definition
-Buproprion (wellbutrin)--dopamine & norepinephrine
-Placebo effects: 30% improve
-Psychotherapy
-Electroconvulsive therapy (ECT)
Term
Bi-Polar Disorder
Definition
-Rapid changing of moods
--Mania to depression
--larger than normal amygdala
--decreased # of neurons in pre-frontal cortex
Term
Treatment for Bi-Polar Disorder
Definition
-lithium (mood stabilizer)
-anti-convulsants
**both block arachidonic acid
Term
Seasonal Affective Disorder
Definition
occurs mainly during winter
-->light therapy increases serotonin
Term
Schizophrenia
Definition
-Develops early to mid 20s
-affects men & women
-severe & persistent neurological disorder
Term
Schizophrenia affects
Definition
perception, thinking, emotions, language, and social behavior
Term
Negative symptoms
Definition
missing a normal behavior
Term
Positive symptoms
Definition
the appearance of abnormal behaviors
Term
Common brain abnormalities in schizophrenic patients
Definition
-larger than normal lateral ventricles
-less activity on the left hemisphere
-smaller left hemisphere
Term
Dopamine Hypothesis
Definition
schizophrenia is due to too much dopamine at some of the dopamine synapses
Term
function of older anti-psychotics
Definition
block dopamine receptors
-->can cause movement problems (EPS)
Term
tardive dyskinesia
Definition
repetitive, involuntary movements
Term
Pseudoparkinsonism
Definition
symptoms that mock Parkinson's
Term
Acute dystonic reaction
Definition
muscle spasms, abnormal postures
Term
Akathisia
Definition
inability to remain still
Term
2nd generation anti-psychotics
Definition
-Increase release of glutamate
-Block 1 serotonin receptor type/block some dopamine receptors
-Cause weight gain but no horrible EPS
-Help alleviate both positive & negative symptoms
-Some risk of immune system damage
Term
Deficient Glutamate hypothesis
Definition
There’s deficient activity at some glutamate synapses, especially in frontal lobe
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