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Pharm- Vasopressors
Drugs
72
Medical
Professional
10/15/2011

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Term
A1, B1, B2, and Dopamin have properties that put them into which ANS?
Definition
sympathomimetic, aka Adrenergic
Term
What is another term for Cholinergic Receptors
Definition
Parasympathomimetic
Term
What's another term for parasympatholytics?
Definition
Cholinergic Blockers
Term
sympathomimetics are also called what, and are part of what system?
Definition
catecholamine and Adrenergic
Term
what two nerve fibers are part of cholinergic
Definition
Muscarinic and Nicotinic
Term
what r Muscarinic effects of ACH
Definition
Term
what r the Nicotinic effects of ACH
Definition
>HR, >BP, >PVR
Term
what inactivates acetylcholine
Definition
acetycholinesterase
Term
what is the prototype drug that effects Adrenergic
Definition
epinepherene
Term
what is the prototype drug for antidysrhythmic vasopressors
Definition
epinephrene
Term
which vasopressor would you choose to give first and why?
Definition
dopamine or dobutamine because it is not as strong as a vasoconstrictor
Term
what happens when u give low dose of dopamine and when would u give it
Definition
renal vasodilation good for drug o.d. and chf w/ pulmonary edema
Term
what happens when u give medium dose of dopamine and when would u give it
Definition
B1 to >ino, chrono, dromo>bp. good first step in >bp because this dose does not >vasoconstriction
Term
what happens when u give high dose of dopamine and when would u give it
Definition
B1 and A1 so vasoconstriction with B1 affects for severe hypotention,
Term
which antidysrhythmic vasopressor do we titrate to bp
Definition
dopamine
Term
when would u use dobutamine vs. dopamine
Definition
when u want to >bp but not hr. I.e., pt is hypotensive and tachycardic
Term
under what condition can u use Vasopressin instead of epi
Definition
cardiac arrest
Term
under what condition are all vasopressors contraindicated
Definition
hypertention and hypovolemia
Term
what do amrinone and milrinone do and who do we use it on
Definition
inotropy on CHF with hypertention because they also vasodilate
Term
name all vasopressors
Definition
epinephrene is prototype, norepi, dopamine, dobutamine, amrinone, milrinone, vasopressin, isoproterenol
Term
when r vasopressors indicated
Definition
hypotension
Term
trade name for epi
Definition
adrenalin
Term
epi's mech of action
Definition
works directly on A and B receptors
Term
indications for epi
Definition
cardiac arrest: asystole, PEA, pulseless V-tach, shock, hypotension
Term
what are contras for epi
Definition
hypertension, hypovolemia, preg, tachydys, hear disease
Term
what are epi's 4 classifications:
Definition
sympathomimetic, catecholamine, inotropic agent, vasopressor
Term
what is the trade name for vasopressin
Definition
Pitressin
Term
vasopressin class
Definition
vasopressor
Term
vasopressin MOA
Definition
smooth muscle constriction and ROSC without >o2 demand
Term
indi for Pitressin
Definition
cardiac arrest: asys, pea, pulseless vtach. to >PVR without worsening MI due to >o2 demand of heart
Term
when is Pitressin used instead of epi
Definition
when u need drug to work more than 3-5 minutes. vasopressin works for 20 minutes
Term
what is trade for dopamine
Definition
intropin
Term
classification of dopamine
Definition
sympathomimetic, catecholamine, vasopressor, inotropic agent
Term
Intropin's generic and MOA
Definition
dopamine acts directly on alpha and beta receptors: ino, chrono, dromo, >automaticity, >sys vascular resistence, >bp, > (renal, coronary, mesenteric- in low doses)
Term
Indications for dopamine- Intropin
Definition
hypotension, shock, symptomatic bradycardia
Term
how is dopamine administered
Definition
IVPB and titrated to BP
Term
dobutamine's trade
Definition
dobutrex
Term
dobutrex's gen name
Definition
dobutamine
Term
dobutamine's classification
Definition
sympathomimetic, inotropic, vassopressor
Term
if dobutrex is a sympathomimetic, ino, vaso, why is it indicated and safe for pt w/ hr
Definition
mild chrono yet significant ino, so it won't >hr that much but will > contraction
Term
indications for dobutamine, why and what is trade
Definition
CHF with hypotension especially w/ tachycardia because ino will push fluids out of lungs w/out >hr. Dobutrex
Term
what drug is safe to give when pt is already tachycardic
Definition
dobutrex or dobutamine because mildly chrono
Term
what is trade for norepi
Definition
Levophed
Term
classification of Levophed, why and gen name
Definition
sympathomimetic and vasopressor because it works on alpha not inotrope
Term
MOA with norepi and trade
Definition
direct alpha, thus >bp and co. levophed
Term
when give levophed, gen name
Definition
shock w/ bp<70. when all other drugs have failed, lasts 40 min. norepi
Term
trade for isoproterenol
Definition
isuprel
Term
which four vasopressors are a and b
Definition
epi, vasopressin, dopamine, dobutamine
Term
which drug is grouped with vasopressor class but is not, and what is it then
Definition
isoproterenol works on beta only
Term
what is class of isoproterenol and trade
Definition
sympathomimetic and Isuprel
Term
Isuprel's MOA and gen name
Definition
beta 1 and 2, >co, bronchodilation. isoproterenol
Term
what doesn't isoproterenol due and what is trade
Definition
because no alpha, won't increase bp through vasoconstriction. isuprel
Term
indications for isoproterenol
Definition
symptomatic bradycardia
Term
trade for amrinone
Definition
Inocor
Term
classification for inocor and gen
Definition
inotropic agent and amrinone
Term
moa for amrinone and trade
Definition
inotrope w mild vasodilator, so reduces pre and afterload
Term
indications for amrinone and trade
Definition
severe CHF with hypertention and refractory to other agents
Term
trade for milrinone
Definition
Primacor
Term
primacor class and gen
Definition
inotrope with mild vasodilator. milrinone
Term
moa for milrinone and trade
Definition
inotrope and vasodilation. primacor
Term
indications for primacor and gen
Definition
severe chf and hypertension
Term
dopamine's trade
Definition
Intropin
Term
classification of dopamine and trade
Definition
sympathomimetic, inotropic agent, vasopressor, catecholamine. Intropine
Term
what is gen name for Intropin
Definition
dopamine
Term
MOA for dopamine
Definition
ino, chrono, dromo, >automat, >pvr, >bp, >renal, mesenteric, coronary- in low doses
Term
indications for dopamine and trade
Definition
significant hypotension, shock, sympto bradycardia
Term
another name for anti-cholenergic
Definition
parasympatholytic
Term
nicotenic effects
Definition
muscle contractions, >hr, >bp
Term
muscarinic
Definition
Term
drug given for muscarinic affects
Definition
atropine
Term
class of drugs that increase bp
Definition
vasopressors
Term
drug that just increases strength of contracitons
Definition
inotropes
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