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Pharmacology
Pharm Psych
23
Medical
Graduate
03/18/2007

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Cards

Term
What are the atypical antipyschotics?
Definition
1. Clozapine
2. Olanzapine
3. Risperidone
Term
How do the Atypical antipsychotics work?
Definition
Block 5HT and Dopamine receptors.
Term
What are the atypical antipsychotic toxicities?
Definition
1. Fewer extrapyramidal system symptoms
2. Fewer anticholinergic effects
3. Clozapine ==> agranulocytosis
Term
Name Lithium toxicities
Definition
1. Hypothyroidism
2. Tremor
3. Polyuria
5. Teratogenic
6. Narrow therapeutic window
Term
Name the SSRI's.
Definition
1. Fluoxetine
2. Setraline
3. Paroxetine
4. Citrolam
Term
What is Seratonin syndrome with MAO inhibitors?
Definition
1. Hyperthermia
2. Muslce rigidity
3. Cardiovascular collapse
Term
What are the side effects to using tricyclic antidepressants?
Definition
1. Sedation
2. Alpha blocking effects
3. Atropine effects
4. Amytriptilline has greater anticholinergic effects.
5. Despiramine has the least sedating
Term
What are the toxicities of tricyclic antidepressants?
Definition
( 3 C's)
1. Cardiotoxicity
2. Coma
3. Convulsions
4. Hyperpyrexia
Term
What are the Parkinson's drugs?
Definition
(BALSA)
1. Bromocriptine
2. Amantadine
3. Levodopa
4. Selegine
5. Antimuscarinics (Benztropine=Cogentin does not help with dyskinesia)
Term
What are the L-Dopa Toxicities?
Definition
1. Arrythmias
2. Dyskinesias
Term
Barbituate Toxicities
Definition
1. Dependance
2. Additive effect with alcohol ==> CNS depression
3. Cardiovascular and Respiratory depression
4. Induction of cytochrome p-450
Term
Name the barbituates.
Definition
1. Phenobarbital
2. Pentobarbital
3. Secobarbital
4. Thiopental
Term
What are the Antipsychotic Drugs? (Neuroleptics)
Definition
1. Thioridizine
2. Haloperidol
3. Fluphenazine
4. Chlopromazine
Term
Whare are the toxcities of Antipsychotics?
Definition
1. Extrapyramidal Side effects
2. Sedation
3. Endocrine effects
4. blocks muscarinic, alpha, histamine receptors
5. Neurolept malignant syndrome
6. Tardive dyskinesia
Term
How do you treat neurolept malignant syndrome?
Definition
Dantrolene and Dopamine agonists
Term
Name the Benzodiazipines
Definition
1. Lorazepam
2. Diazapam
3. Temazapam
4. triazolam
5. oxazepam
6. midozolam
Term
Which are the short acting benzodiazipines?
Definition
(TOM's thumbs)
1. Triazolam
2. Oxazepam
3. Midozalam
Term
What is the mechanism of action of Selegine?
Definition
Inhibits MAO-B
Term
Epileptic drugs that cause the Induction of cytochrome p450
Definition
1. Carbamazepime
2. Phenobarbital
Term
Epileptic drugs causing hepatotoxicity.
Definition
1. Carbemazapime
2. Valproic Acid
Term
Drugs causing gingival hyperplasia
Definition
1. phenytoin
2. nifedipine
3. cyclosporin
Term
Epileptic drugs causing GI distress.
Definition
1. Ethosuxamide
2. Valproic Acid
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