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Pharmacology
Test #5
42
Medical
Not Applicable
06/11/2004

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Cards

Term
Name some lifestyle changes for a person with HTN
Definition
wt loss, Na+ restriction, DASH, Alcohol and nicotine reduction, exercise, adequate K+ and Ca++
Term
What is hyponatremia and hypokalemia
Definition
low salt and low K+
Term
What does Furosemide do?
What kind of drug is it?
Definition
Block readsorption of Na+ and Cl-.
High ceiling Loop diuretic
Term
What is Furosemide used to treat?
Definition
pulmonary edema, heart failure, HTN, edema and renal failure
Term
Side effects of Furosemide
Definition
ototoxicity, shock, fluid and electrolyte changes
Term
Can you use Furosemide during pregnancy?
Definition
No
Term
Which is more potent: High ceiling loop diuretics or Thiazides?
Definition
High ceiling loop diuretics
Term
What does Hydrochlorthiazide treat?
Hydrochlorthiazide is a dericative of what?
Definition
HTN and edema.
Sulfa
Term
Name some Nsg interventions for a patient taking a Thiazide
Definition
Reduce salt intake, Monitor BP and pulse, get up slowly, eat OJ and bananas, teach to eat foods with K+
Term
What does Spironolactone do?
What is it used for?
Definition
Blocks aldosterone in kidneys.
HTN and edema
Term
Side effects of Spironolactone
Definition
hyperkalemia, neuroendocrine changes
Term
When taking Spironolactone what do you want to advoid eating?
Definition
Avoid other K+ savers and eat a salt substitute (KCL) instead of regular salt.
Term
1.) What are some used of osmotic diuretics?
2.) What can they cause?
Definition
1.) renal failure, decrease ICP, reduce IOP. 2.) Edema
Term
What is the role of AngiotensionII?
Definition
vasoconstriction, release of aldosterone and remodeling of CV
Term
What are some uses for ACE's?
Definition
HTN, heart failure, diabetic nephropathy, prevent MI and Stroke
Term
What kind of drug is Captopril?
diuretic, ACE, CCB or cholesterol lowering drug
Definition
ACE
Term
Side effects of Captopril?
Definition
First dose hypotension, cough, hyperkalemia, renal failure and fetal injury
Term
What are some uses for Angiotension Receptor Blockers (ARB)?
Definition
HTN, heart failure, diabetic nephropathy
Term
Side effects of ARB's
Definition
angioedema, fetal harm and renal failure
Term
What is the prototype for the ARB's
Definition
Losartan
Term
1.) What kind of drugs are Verapamil and nifedipine?
2.) What does each work on in the body?
Definition
1.) Ca+ channel blockers (slow down HR)
2.) Verapamil: heart and VSM
Nifedipine: VSM
Term
Since CCB slow down the HR what can they be used to treat?
Definition
tachydysrhythmias, migraines, angina and HTN
Term
What would happen if you mixed CCB and BB or Digoxin?
Definition
Result in bradycardia and have similar effect
Term
Side effects of CCB's?
Definition
constipation, flushing, headache, dizziness, and peripheral edema
Term
If a patient misses a dose of Nifedipine what do you need to watch for?
Definition
Reflex tachycardia
Term
What is the #1 nsg intervention when a patient is taking Digoxin?
Definition
Monitor pulse, hold med if HR <60 and teach pt. the same.
Term
What is the therapeutic range of Digoxin?
Definition
0.5 to 1.1 ng/ml for maintance
Term
What are some side effects of Digoxin?
Definition
N/V, malaise, visual disturbances and anorexia
Term
What kind of drugs are the statins?
What do they do?
Definition
Cholesterol lowering agents, Reduce LDL and raise HDL
Term
Side effects of Statins?
Can be used in pregnancy?
Definition
Hepatotoxicty and myopathy
PG: NO!
Term
1.) What type of drug is Nicotinic Acid?
2.) What does it do?
Definition
1.) Cholesterol lowering agent
2.) Reduces LDL(5-25%) and Triglycerides (20-50%), increases HDL (BEST) (15-35%)
Term
Side effects of Nicotinic Acid (3)
Definition
itching, gi upset, hepatotoxicity
Term
What do bile acid sequestrants do?
Definition
Act as Pacman and block absorption,
Lowers LDL (20%)
Term
What are some side effects of Bile acid sequestrants? (3)
Definition
constipation, bloating and foul farting
Term
Main use of Nitroglycerin is?
What are some side effects?
Definition
Angina///
SE: headache, hypotension, and reflex tachycardia
Term
What will happen if you mix NTG with Viagra together?
Definition
Profound hypotension
Term
What do these mean?
anticoagulant
thrombolytics
antiplatelet
Definition
1.) blocks clotting
2.) dissolves clot
3.) blocks platelet aggregation
Term
What do you use if someone is toxic with Heparin?
Definition
protamine sulfate
Term
Why can Heprain be used during pregnancy?
Definition
does not cross the BBB or placenta
Term
What is the antidote for Warfarin?
Can it be used during pregnancy?
Definition
Vitamin K////
NO
Term
Which is lipid soluble and which is not: Heparin or Warfarin?
Definition
Warfarin is lipid soluble Cannot be given during pregnancy
Term
What are some side effects for Fibrates?
Definition
gallstones, myopathy, and liver injury
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