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Pharmacology
pharmacodynamics, pharmacokinetics, pharmacotherapeutics
46
Nursing
Undergraduate 1
03/02/2011

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Cards

Term
Pharmacology
Definition
Scientific study of the origin, nature, chemistry effects and use of drugs
Term

Trade name

 

Definition

proprietary name

selected by drug company

Term
Scientific name
Definition
name that describes the chemical and molecular structure of medication
Term

Generic name

 

Definition

abbreviation of the chemical name

(should be using)

Term
Pharmacological Class groups drugs by
Definition
shared characteristics
Term
Therapeutic Class groups drugs by
Definition
There therapeutic use
Term
Drug sources
Definition

plant 

animal

mineral

synthetic

Term
Plant sources
Definition

alkaloids

glycosides

gums

resin

oil

Term
Animal sources
Definition

hormones

oil/fats

enzymes

vaccines

Term
Mineral sources
Definition

metallic

non-metallic

Term
Most alkaloids end in?
Definition

"ine"

examples= caffeine

                nicotine

                 atropine

Term

Glycosides end in?

 

Definition

"in"

example=Digoxin

Term
Administrations routes
Definition

Buccal

sublingual

translingual

intradermal

intramuscular

intravenous

oral

rectal/vaginal

respiratory

subcutaneous

topical 

special

Term
Where is Lovinox given?
Definition
can only be given subcutaneously
Term
Pharamacokinetics
Definition

absorption

distribution

metabolism

excretion

of drugs by the body

Term
Pharmacodynamics
Definition
biochemical and physical effects of drugs and the mechanism of drug action
Term
Pharmacotherapeutics
Definition
The use of drugs to prevent and treat disease
Term
Absorption
Definition

way it's taken into the body

 

Passive= move from higher to lower concentration via diffusion

 

Active= move from lower to higher concentration via cellular energy

Term
Fastest Absorption Rate
Definition

Sublingual

Inhalors

Intravenous

Term
Slowest Absorption Rate
Definition
enteric coded
Term
Factors affecting absorption
Definition

Administration/ drug form

Intestinal interference

liver metabolism

blood flow

pain/stress

diet

drug combination

Term
Factors affecting distribution
Definition

Blood flow- faster flow faster distribution

solubility- water/fat soluble

Protein binding- albumin binding

Term
99%of drugs metabolized where?
Definition
The liver
Term
Factors affecting metabolism
Definition

Disease

genetics

environment

age

Term
99% of excretion thru what?
Definition
The kidney
Term
Drug 1/2 life
Definition
Time it takes for 1/2 of the drug to be eliminated (excreted)
Term
1/2 life is a factor for?
Definition
Dosing frequency
Term
Factors affecting 1/2 life?
Definition

absorption

metabolism

excretion

Term
POD
Definition

Peak

onset

duration

Term
Peak
Definition
highest concentration
Term
Onset
Definition
time from administration until effect begins
Term
Duration
Definition

time of therapeutic effect

(length of time it's working)

Term
Peak and Trough
Definition
Test to measure therapeutic level
Term
trough
Definition
level of med 30 minutes before next dose due
Term
Agonist
Definition
interacts with receptors binds to produce effects called intrinsic activity
Term
Antagonist
Definition

Competitive=competes with agonist for receptor site

 

or

 

Noncompetitive= bind to receptor sites and blocks the effects of the agonist

Term
drug potency
Definition
the amount of the drug required to produce a desired response
Term
Therapies
Definition

Acute

Empiric

Maintenance

Supplemental/Replacement

Supportive

Palliative

Term
Factors affecting drug response
Definition

Age

diet

dx

other meds

gender infection

OI/CV/Renal/Hepatic Function

Term
Drug Tolerance
Definition
A patient has a lower response to a drug over time
Term
Drug dependence
Definition
a patient displays a physical or psychological need for a drug
Term
Potential drug interactions
Definition

additive

potentiation

antagonistic

slower or faster absorption

slower or faster metabolism

slower or faster excretion

Term
Dose related reactions
Definition

Secondary effects

hypersusceptibility

overdose iatrogenic effect

Term
Patient sensitive adverse reactions
Definition

Drug Allergy

mild

anophylactic

 

or

 

Idiosyncratic

Term
Adverse drug reaction/side effect
Definition
a harmful undesirable response
Term
TERM DPARTD
Definition

Time Evaluation Route Medication

Dose Patient Assessment Refusal Teaching Documentation

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