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Pharmacology
Chapter 21- Chabner- The Language of Medicine
244
Medical
Undergraduate 1
03/05/2013

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Term
aer/o
Definition
air
Term
alges/o
Definition
sensitivity to pain
Term
bronch/o
Definition
bronchial tube
Term
chem/o
Definition
drug
Term
cras/o
Definition
mixture
Term
cutane/o
Definition
skin
Term
derm/o
Definition
skin
Term
erg/o
Definition
work
Term
esthes/o
Definition
feeling, sensation
Term
esthes/o
Definition
feeling, sensation
Term
hist/o
Definition
tissue
Term
hypn/o
Definition
sleep
Term
iatr/o
Definition
treatment
Term
lingu/o
Definition
tongue
Term
myc/o
Definition
mold, fungus
Term
narc/o
Definition
stupor
Term
or/o
Definition
mouth
Term
pharmac/o
Definition
drug
Term
prurit/o
Definition
itching
Term
pyret/o
Definition
fever
Term
thec/o
Definition
sheath (of brain and spinal cord)
Term
tox/o
Definition
poison
Term
toxic/o
Definition
poison
Term
vas/o
Definition
vessel
Term
ven/o
Definition
vein
Term
vit/o
Definition
life
Term
ana-
Definition
upward, excessive, again
Term
anti-
Definition
against
Term
contra-
Definition
against, opposite
Term
par-
Definition
other than, apart from
Term
syn-
Definition
together, with
Term
a.c., ac
Definition
before meals (ante cibum)
Term
ACE
Definition
angiotensin-converting enzyme
Term
ad lib
Definition
freely, as desired (ad libitum)
Term
APAP
Definition
acetaminophen (Tylenol)
Term
ARB
Definition
angiotensin II receptor blocker
Term
bid, b.i.d.
Definition
two times a day (bis in die)
Term
Definition
with
Term
Caps
Definition
capsules
Term
cc
Definition
cubic centimeter
Term
FDA
Definition
U.S. Food and Drug Administration
Term
gm, g
Definition
gram
Term
gtt
Definition
drops (guttae)
Term
h
Definition
hour (hora)
Term
h.s., hs
Definition
at bedtime (hora somni)
Term
h2 blocker
Definition
histamine h2 receptor antagonist
Term
HRT
Definition
hormone replacement therapy
Term
IM
Definition
intramuscular
Term
INH
Definition
isoniazid- antituberculosis agent
Term
IV
Definition
intravenous
Term
MAOI
Definition
monoamine oxidase inhibitor - an antidepressant
Term
mg
Definition
milligram
Term
ml
Definition
milliliter
Term
NPO
Definition
nothing by mouth (nil per os)
Term
NSAID
Definition
nonsteroidal anti-inflammatory drug
Term
p-
Definition
after (post)
Term
pc, p.c.
Definition
after melas (post cibum)
Term
PCA
Definition
patient-controlled analgesia
Term
PDR
Definition
Physicians Desk Reference
Term
PO, p.o., po
Definition
by mouth (per os)
Term
p.r.n/ PRN
Definition
as needed; as necessary (pro re nata, as the occasion arises)
Term
Pt
Definition
patient
Term
q
Definition
every (quaque)
Term
qh, g.h.
Definition
every hours (quaque hora)
Term
qh2
Definition
every 2 hours
Term
qid, q.i.d
Definition
four times a day (quater in die)
Term
qs, q.s.
Definition
sufficient quantity (quantum satis)
Term
qAM
Definition
every morning
Term
qPM
Definition
every evening
Term
Rx
Definition
prescribtion
Term
s-
Definition
without (sine)
Term
SERM
Definition
selective estrogen receptor modulator
Term
Sig.
Definition
directions- hot to take medication
Term
SL
Definition
sublingual
Term
s.o.s.
Definition
if it is necessary (si opus sit)
Term
SSRI
Definition
selective serotonin reuptake inhibitor- an antidepresaant
Term
SQ
Definition
subcutaneous
Term
tab
Definition
tablet
Term
TCA
Definition
tricyclic antidepressant
Term
tid, t.i.d
Definition
three times daily (ter in die)
Term
aerosol
Definition
Particles of drug (in solution) suspended in air.
Term
analgesic
Definition
Pertaining to without sensitivity to pain.
Term
bronchodilator
Definition
Drug that relaxes the smooth muscle lining bronchial tubes and is used to treat asthma, emphysema, and chronic bronchitis.
Term
chemotherapy
Definition
Treatment using drugs.
Term
idiosyncrasy
Definition
An unexpected effect of a drug that is peculiar to an individual.
Term
subcutaneous
Definition
Pertaining to under the skin.
Term
hypodermic
Definition
Pertaining to under the skin.
Term
synergism
Definition
Condition of working together; the drug action in which the combination of two
drugs causes an effect that is greater than the sum of the individual effects of each drug alone.
Term
anesthesia
Definition
Condition of being without nervous sensation.
Term
antihistamine
Definition
An agent that acts against histamine production in the body. Histamine is
released as a result of an allergic reaction.
Term
hypnotic
Definition
Pertaining to a condition of sleep (a trance-like state).
Term
iatrogenic
Definition
Pertaining to an adverse condition that is caused or produced by a physician or a specific treatment.
Term
sublingual
Definition
Pertaining to under the tongue.
Term
erythromycin
Definition
An antibiotic that is produced from a red (erythr/o) mold (myc/o).
Term
narcotic
Definition
Pertaining to a substance that produces stupor (has a morphine- or opium-like
action).
Term
oral
Definition
Pertaining to the mouth.
Term
pharmacology
Definition
Study of drugs
Term
antipruritic
Definition
Pertaining to an agent that acts to relieve itching
Term
antipyretic
Definition
Pertaining to an agent that acts to relieve fever.
Term
intrathecal
Definition
Pertaining to within the sheath of membranes surrounding the spinal cord
Term
toxic
Definition
Pertaining to poison.
Term
toxicology
Definition
Study of poisons and the harmful effects of drugs.
Term
vasodilator
Definition
Substance that causes blood vessels to widen.
Term
intravenous
Definition
Pertaining to within a vein.
Term
vitamin
Definition
A substance in foods that is essential in small quantities for growth and good
health (life-giving amines).
Term
anaphylaxis
Definition
A hypersensitive state of the body to a foreign protein (antigen) or drug; can
produce severe symptoms and shock.
Term
antidote
Definition
An agent given to counteract unwanted effect of a drug.
Term
antibiotic
Definition
A substance that acts against microorganisms, such as bacteria.
Term
contraindication
Definition
Factor in the patient’s condition that prevents the use of a drug or treatment.
Term
parenteral
Definition
Pertaining to injection of drugs other than through the intestines.
Term
synergistic
Definition
Pertaining to synergism (the drug action in which the sum of the effects of giving two drugs together is greater than that of giving each drug alone).
Term
ACE inhibitor
Definition
Drug that lowers blood pressure (antihypertensive).
Term
Addiction
Definition
Physical and psychologic dependence on and craving for a drug.
Term
Additive action
Definition
Combination of two similar drugs is equal to the sum of the effects of each.
Term
Aerosol
Definition
Particles of drug suspended in air
Term
Amphetamine
Definition
Central nervous system stimulant
Term
Analgesic
Definition
Drug that relieves pain
Term
Anaphylaxis
Definition
Exaggerated hypersensitivity reaction to a previously encountered drug or to a foreign protein (antigen).
Term
Androgen
Definition
Male hormone
Term
Anesthesia
Definition
Absence of nervous feeling or sensation
Term
Anesthetic
Definition
Drug that reduces or eliminates nervous sensation
Term
Angiotensin II receptor blocker
Definition
Drug that lowers blood pressure by preventing angiotensin from acting on receptors in blood vessels
Term
Antacid
Definition
Drug that works against acid in the stomach.
Term
Antagonistic action
Definition
Combination of two drugs gives less than the sum of the effects of each together.
Term
Antiandrogen
Definition
Drug that slows the uptake of androgens or interferes with their effect in tissues.
Term
Antiarrhythmic
Definition
Drug that treats abnormal heart rhythms.
Term
Antibiotic
Definition
Chemical substance that has the ability to inhibit or destroy foreign organisms in the body.
Term
Anticoagulant
Definition
Drug that prevents blood clotting
Term
Anticonvulsant
Definition
Drug that prevents convulsions and seizures.
Term
Antidepressant
Definition
Drug that relieves symptoms of depression.
Term
Antidiabetic
Definition
Drug given to prevent or treat diabetes mellitus.
Term
Antidiarrheal
Definition
Drug that prevents diarrhea
Term
Antidote
Definition
Agent given to counteract an unwanted effect of a drug.
Term
Antiemetic
Definition
Drug that prevents nausea and vomiting.
Term
Antihistamine
Definition
Drug that blocks the action of histamine and helps prevent symptoms of allergy.
Term
Antinauseant
Definition
Drug that relieves nausea and vomiting; antiemetic.
Term
Antiplatelet
Definition
Drug that reduces the tendency of platelets to stick together and form a clot.
Term
Antipruritic
Definition
Drug that acts against itching (pruritus).
Term
Antipyretic
Definition
Drug that lowers fever
Term
Antiulcer
Definition
Drug that inhibits the secretion of acid by cells lining the stomach
Term
Antiviral
Definition
Drug that acts against viruses such as the herpes virus and HIV.
Term
Aromatase inhibitor
Definition
Drug that reduces estrogen in the blood by blocking the enzyme, aromatase.
Term
Bactericidal
Definition
Pertaining to killing bacteria
Term
Bacteriostatic
Definition
Pertaining to inhibiting bacterial growth
Term
Beta-blocker
Definition
Blocks the action of epinephrine (adrenaline) on the heart and blood vessels and thus lowers blood pressure
Term
Bronchodilator
Definition
Agent that dilates (widens) blood vessels and relieves bronchospasm.
Term
Bisphosphonate
Definition
Drug that prevents bone loss in osteoporosis and osteopenia.
Term
Brand name
Definition
Commercial name for a drug; trade or trademark name.
Term
Caffeine
Definition
Central nervous system stimulant.
Term
Calcium channel blocker
Definition
Drug that stops entrance of calcium into muscle of the heart and blood vessels. This lowers blood pressure and restores normal heart rhythm.
Term
Cardiac glycoside
Definition
Drugs which increase the force of contractions of the heart.
Term
Cardiovascular drug
Definition
Pertaining to the heart and blood vessels. Cardiovascular drugs act on the heart and blood vessels; ACE inhibitors, diuretics, beta-blockers, statins.
Term
Cathartic
Definition
Drug that relieves constipation.
Term
Chemical name
Definition
Chemical formula for a drug.
Term
Chemotherapy
Definition
Treatment with drugs.
Term
Cholesterol-binding drug
Definition
Binds to dietary cholesterol and prevents its uptake from the GI tract.
Term
Cholesterol-lowering drug
Definition
Controls hypercholesterolemia (high levels of cholesterol in the blood); statin
Term
Contraindications
Definition
Factors in a patient’s condition that prevent the use of a particular drug or treatment.
Term
Controlled substances
Definition
Drugs that produce tolerance and dependence and have potential for abuse or addiction.
Term
Diuretic
Definition
Drug that promotes or increases the production of urine (diuresis).
Term
Dose
Definition
Amount of drug administered.
Term
Emetic
Definition
Drug that promotes vomiting.
Term
Endocrine drug
Definition
Pertaining to internal secretion. An endocrine drug is a hormone or hormone-like drug; androgens, estrogens, glucocorticoids.
Term
Erythromycin
Definition
Antibiotic that is extracted from a red (erythr/o) mold (-mycin).
Term
Estrogen
Definition
Female hormone that promotes secondary sex characteristics and supports reproductive tissues.
Term
Gastrointestinal drug
Definition
Pertaining to the stomach and intestinal tract (intestines). Gastrointestinal drugs include antiulcer, antidiarrheal, and antacid medications.
Term
Generic name
Definition
Legal, noncommercial name for a drug.
Term
Glucocorticoid
Definition
Hormone from the adrenal cortex that raises blood sugar and reduces tissue inflammation.
Term
Hypnotic
Definition
Drug that promotes sleep or a trance-like state (hypnosis).
Term
Hypodermic
Definition
Pertaining to under the skin
Term
Iatrogenic
Definition
Pertaining to a condition that is produced (-genic) by a physician or treatment (iatr/o).
Term
Idiosyncrasy
Definition
Unexpected effect produced in a particularly sensitive individual, but not seen in most patients.
Term
Idiosyncratic reaction
Definition
Unexpected effect produced in a particularly sensitive patient but not seen in most people.
Term
Inhalation
Definition
Administration of drugs in gaseous or vapor form through the nose or mouth.
Term
Intrathecal
Definition
Pertaining to within the meninges or membranes surrounding the spinal cord. Drugs may be administered intrathecally.
Term
Laxative
Definition
Weak cathartic; promotes movement of feces through the colon.
Term
Medicinal chemistry
Definition
Study of new drug synthesis and the relationship between the chemical structure of a drug and its biologic effect.
Term
Molecular pharmacology
Definition
Study of the interaction of drugs and their target molecules, enzymes, or cell surface receptors
Term
Narcotic
Definition
Habit-forming drug that relieves pain by producing stupor and insensibility; morphine and opium.
Term
Oral administration
Definition
Drugs that are given by mouth.
Term
Parenteral administration
Definition
Drugs or nourishment are given intravenously (within a vein) and other than through the intestinal tract.
Term
Pharmacist
Definition
Specialist in preparing and dispensing drug.
Term
Pharmacy
Definition
Location for preparing and dispensing drugs; study of preparing and dispensing drugs.
Term
Pharmacodynamics
Definition
Study of the effects and strength of a drug within the body.
Term
Pharmacokinetics
Definition
Calculation of drug concentration in tissues and body fluids over a period of time.
Term
Pharmacologist
Definition
Specialist in the study of the properties, uses, and actions of drugs.
Term
Pharmacology
Definition
Study of the properties, uses and actions of drugs.
Term
Progestin
Definition
Hormone that stimulates the uterine lining during pregnancy and is used in treatment of abnormal uterine bleeding and hormone replacement therapy.
Term
Purgative
Definition
Drug that relieves constipation and is a strong cathartic.
Term
Receptor
Definition
Target substance with which a drug interacts in the body.
Term
Rectal administration
Definition
Drugs are inserted through the anus into the rectum.
Term
Resistance
Definition
Lack of beneficial response; see when drugs are unable to control the disease process.
Term
Respiratory drug
Definition
Treats asthma, emphysema, and infections that affect breathing; bronchodilators are respiratory drugs.
Term
Response
Definition
Desired and beneficial effect of a drug.
Term
Schedule
Definition
Exact timing and frequency of drug administration.
Term
Sedative
Definition
Mild sleep inducing agent that relaxes a patient without necessarily producing sleep.
Term
Side effect
Definition
Adverse effect that routinely results from the use of a drug.
Term
Stimulant
Definition
Drug that excites and promotes activity.
Term
Subcutaneous
Definition
Pertaining to under the skin.
Term
Sublingual
Definition
Pertaining to under the tongue.
Term
Synergism
Definition
Drug action in which the combination of two drugs causes an effect that is greater than the sum of the individual effects of each drug.
Term
Synergistic
Definition
Pertaining to synergism.
Term
Syringe
Definition
Instrument for introducing or withdrawing fluids from the body.
Term
Thyroid hormone
Definition
Secretion from the thyroid gland that stimulates cellular metabolism.
Term
Tolerance
Definition
Drug action in which larger and larger doses must be given to achieve a desired effect.
Term
Topical application
Definition
Drugs are applied locally on the skin or mucous membranes of the body; ointments, lotions, and creams are examples.
Term
Toxicity
Definition
Harmful effect of a drug.
Term
Toxicology
Definition
Branch of pharmacology that studies harmful chemicals and their effects on the body.
Term
Tranquilizer
Definition
Drug that controls anxiety and severe disturbances of behavior.
Term
Transport
Definition
Movement of a drug across a cell membrane into body cells.
Term
Vasodilator
Definition
Drug that widens blood vessels.
Term
Vitamin
Definition
Substance found in foods and essential in small quantities for growth and good health.
Term
drug sources:
Definition
1. plants (foxglove (digitalis), yew tree (taxol)
2. animals (pregnant mare's urine--Premarin)
3. synthetic
4. food substances (vitamins)
Term
Pharmacology is the broad specialty with subspecialties of:
Definition
· medical chemistry
· pharmacodynamics (drug absorption, metabolism, excretion)
· pharmacokinetics
· chemotherapy
· molecular pharmacology
· toxicology
Term
All drugs have 3 different names:
Definition
1. brand name (denoted by TM or registered mark) also known as proprietary name. Only 1 drug company can use a particular brand name.
2. generic name (often describes the chemical name) becomes public property after 17 years.
3. organic or chemical name (describes chemical compound of drug) that may contain letters and/or numbers of chemical ingredients.
Term
Legislation Dates of Importance:
Definition
1906 Pure Food and Drug Act: a drug has to have a label that indicated what was in the drug.
1970 Controlled Substances Act: establishes the DEA (Drug Enforcement Agency).
1983 Orphan Drug Act: government provides tax incentives for drug companies to research and develop drugs that may only be used by a small portion of the population for a rare disease.
Term
Drug References Used Most Often by Professionals:
Definition
1.USP: United States Pharmacopeia is the most authoritative reference containing every drug currently approved by the FDA.

2. Hospital Formulary: simply a list of all the drugs authorized for prescribing within a certain health care system. For example, the Kaiser system has a list of every drug that can be prescribed by Kaiser providers that will be paid for by the company. Any drug prescribed that is not in this formulary will not be paid for by Kaiser and the patient will be responsible for paying the entire cost.

3. PDR: drug companies pay this private company to publish drug information in this book. May be incomplete and not the best reference.
Term
Administration of Drugs:
Definition
1. tablets: least costly, easiest to use but takes longest to get drug to its target
2. sublingual: under the tongue
3. rectal: use of suppository when unable to use oral route or for local action in mucosa of rectum
4. parenteral: includes all types of injections such as ID, SQ, IM, IV (fastest route), intrathecal, intracavitary
5. inhalation: use of aerosols
6. topical: use of creams, etc.
Term
1. additive action:
Definition
2+2=4 Combination of two drugs is equal to the sum of each.
Term
2. synergism/potentiation:
Definition
2+2=5 Combination of two drugs is greater than each given individually.
Term
3. idiosyncrasy:
Definition
an unexpected effect; i.e., anaphylaxis
Term
4. iatrogenic:
Definition
an effect produced by treatment; i.e., a yeast infection after taking antibiotics
Term
5. side effects:
Definition
routine toxic effects of a drug that can often be seen with use of a drug; i.e., nausea/vomiting
Term
6. contraindication:
Definition
factors in a patient's condition that make use of a drug dangerous; i.e., use of drugs in pregnancy
Term
7. per os:
Definition
by mouth
Term
analgesics:
Definition
relieve pain; i.e., morphine, hydrocodone w/APAP, and NSAID (non-steroidal anti-inflammatory) such as ibuprofen (Advil/Motrin)
Term
antibiotics
Definition
inhibit or stop growth of bacteria, fungi, or parasites; i.e., penicillin. or amoxicillin
Term
anesthetics:
Definition
reduces or eliminates sensation either in a particular area or throughout the entire body
Term
anticoagulants:
Definition
prevent blood clotting; i.e., heparin. or warfarin
Term
antianginal:
Definition
A drug tha prevents chest pain due to ischemia
Term
anticonvulsants:
Definition
prevent and/or decrease severity of convulsions used to treat epilepsy
Term
antidepressants:
Definition
treat symptoms of depression
Term
antidiabetics:
Definition
insulin replaces natural insulin for Type I (IDDM), and oral drugs stimulate production of insulin in the pancreas or supress glucose production in the liver for Type II (NIIDDM)
Term
antihistamines:
Definition
block the action of histamine
Term
Beta blockers
Definition
are a type of antiarrhythmic drug that block the action of epinephrine in the heart muscle and blood vessel walls
Term
Endocrine Drugs
Definition
Used to replace hormones, treat specific diseases and conditions (cancer) and can also be used to provide contraception -- estrogen (Premarin) and progestins (Provera).
Term
Gastrointestinal Drugs
Definition
Can be used to neutralize or block secretion of HCl, relieve diarrhea, n&v, vertigo, and relieve constipation.
Term
barbiturates:
Definition
habit forming
Term
sedatives:
Definition
used to calm and relax. but do not always produce sleep. Most depress the CNS (zolpidem (Ambien)
Term
hypnotics:
Definition
used to produce sleep
Term
caffeine
Definition
(used to treat migraine headaches) and causes vasoconstriction.
Term
dexedrine
Definition
a type of amphetamine) used to treat Attention Deficit/Hyperactivity Disorder (ADHD) and ADD)
Term
methylphenidate
Definition
(Ritalin another stimulant used to treat Attention Deficit/Hyperactivity Disorder (ADHD) and ADD).
Term
minor tranquilizers
Definition
used to control severe anxiety and disturbances in behavior in the treatment of neurosis (a state of increased anxiety) and major tranquilizers used to treat psychosis (loss of contact with reality).
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