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Pharmacology Test #1
Analgesics
37
Nursing
Graduate
09/01/2011

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Cards

Term
pain threshold
Definition
level of stimulus needed to produce the perception of pain
Term
Pain tolerance
Definition
Amount of pain a patient can endure without its interfering with normal function
Term
Breakthrough pain
Definition
when patients have pain requiring additional pain medication between scheduled pain meds
Term
physical dependence
Definition
body adapts to the presence of the drug an withdrawal symptoms occur
Term
medication tolerance
Definition
leads to the need for progressively higher dosages to maintain the same analegesic effect
Term
6 factors to choosing the right analgesic
Definition
1. effectiveness
2. Duration
3. desired duration
4. drug interactions
5. hypersensitivity
6. available routes
Term
Kappa receptor
Definition
produce sedation, dysphoria, myosis, inhibition of ADH release
Term
MU receptor
Definition
-causes respiratory depression , dependence, myosis, euphoria, reduced GI motility, sedation
Term
indications for narcaotic analgesics
Definition
1. alleviate moderate to severe pain
2. cough center surpression
3. Treatment of diarrhea
4. Balanced anesthesia
Term
Morphine
Definition
-inhibits pain perception
-interactions: alcohol, sedatives, antipsycotices, muscle relaxants and
-contra: resp. depression and bile duct cancer
Term
Fentanyl Citrate
Definition
-stronger than morphine
-epidurals
-metabolized in the liver
Term
codeine
Definition
commonly used as a cough suppressant
-usually combined with tylenol or aspirin
Term
oxycodone
Definition
-acetaminophen and aspirin
-trade name percocet
Term
oxycontin
Definition
controlled release oxycodone
Term
hydrocodone
Definition
-hydrocodone plus acetaminophen, aspirin, or ibuprofen
Term
methadone
Definition
used as opioid addiction maintenance for relief of chronic pain
Term
antidepressant
Definition
elavil
Term
antiseizure
Definition
neurontin
tegretol
dilantin
Term
SSRI
Definition
-Selective serotonin re-uptake inhibitor (SSRI)
-celexa, prozac, Zoloft
Term
corticosteroids
Definition
decadron
Term
muscle relaxants
Definition
valium, ativan
Term
Narcan
Definition
-reversal of opioid induced respiratory depression
-onset 1-2 min IV(lasts 1hr) or 2-5 min IM (lasts up to 4 hrs)
Term
acetylcysteine
Definition
treatment for nonopioid drug overdose
Term
acetaminophen
Definition
-analgesic and antipyretic
-non salicylate
Term
Ziconotide
Definition
-intrathecal
-indicated for severe chronic pain
Term
what are two classes that treat headaches?
Definition
1. Serotonin receptor agonist
2. Ergot alkaloids
Term
what are two classes that treat headaches?
Definition
1. Serotonin receptor agonist
2. Ergot alkaloids
Term
triptans
Definition
-stimulate receptors causing vasoconstriction
-reduces number of inflammatory peptides
-absorptive drug
Term
Ergot Alkaloids
Definition
narrows/constricts blood vessels
Term
Imitrex
Definition
-most commonly prescribed drug of class
-contra in patients with CAD and HTN
Term
ergotism
Definition
-ergot toxicity
-muscle spasm, weakness, tingling, cold pale extremities
Term
prostaglandins
Definition
-activated inflammatory response
-stimulates constriction and clotting of platelets
-induction of labor
-inhibit acid synthesis
-
Term
other names for aspirin
Definition
Bufferin
Ecotrin
Anacin
Term
gout
Definition
underexcretion and overproduction of uric acid
Term
allopurinol
Definition
-inhibits xanthine oxidase
-no anti-inflammatory effect
-increase fluids
-contra- alcohol, caffeine, thiazide diuretics
Term
Colchicine
Definition
-for acute attacks of gout
-no fluid loss
-reduces inflammatory response
-contra: renal, cardia, or GI problems
Term
Uricosurics
Definition
-increase uric acid excretion
-effective in alleviating chronic gout
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