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Details

Pharmacology Test #1
Antimicrobials, etc.
28
Medical
Graduate
02/06/2008

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Cards

Term
What happens to the pH in the stomach during pregnancy?
Definition
increases
Term
Does volume of distribution increase or decrease during pregnancy and why?
Definition
increases due to increased plasma volume
Term
T or F. A drug in the B class carries no risk for a pregnancy.
Definition
False
Term
When should you start cortisteroid therapy when there is a risk of preterm delivery?
Definition
24 weeks
Term
What are the two leading causes of morbidity/mortality in the preterm neonate?
Definition
RDS and intracranial hemorrhage
Term
Is effectiveness or efficacy tested during phase III?
Definition
efficacy
Term
What type of ADE is hypotension from administration of an antihypertensive medication?
Definition
Type A
Term
What type of ADE is an anaphylactic reaction?
Definition
Type B
Term
Persons of Ethiopian and Saudi Arabian descent have _______ CYP2D6.
Definition
high amounts
Term
T or F. Codeine's effects will be increased in individuals who lack functional CYP2D6.
Definition
false
Term
T or F. Codeine's effects will be increased in individuals who have increased functional CYP2D6.
Definition
true
Term
What is a positive KOH test diagnostic for?
Definition
fungal infection
Term
T or F. Serum concentrations of a pharmacological agent reflect the MIC.
Definition
False
Term
T or F. Sinusitis usually does not require antibiotics.
Definition
True
Term
What is the difference between a sign and a symptom?
Definition
Sign: what clinician measures
Symptom: what patient feels
Term
What test can be used to ID Tuberculosis?
Definition
acid-fast
Term
What class of antibiotics has cross-reactivity with penicillin?
Definition
Cephalosporin
Term
Time above MIC is most important in concentration independent or dependent drugs?
Definition
independent
Term
Which drug classes are concentration dependent?
Definition
aminoglycosides, fluoroquinolones
Term
What drugs are concentration independent?
Definition
beta-lactam, macrolides, azalides, vanc
Term
What is the most suitable agent for treating animal and human bites?
Definition
Augmentin
Term
At what dosing does CNS side effects become a major concern in penicillin tx?
Definition
20000 units
Term
What are the 1st generation cephalosporins listed?
Definition
cefadroxil, cefazolin, cephalexin, ephradine
Term
What are the 2nd generation oral cephalosporins?
Definition
cefprozil, cefuroxime, cefaclor
Term
What are the parenteral 2nd generation cephalosporins?
Definition
cefoxitin, cefotetan, cefmetazole, carbacephem
Term
What are the oral 3rd generation cephalosporins?
Definition
Cefdinir, cefditoren, cefixime, cefpodoxime, ceftibuten
Term
What are the parenteral 3rd generation cephalosporins?
Definition
ceftizoxime, ceftriaxone
Term
What is the parenteral 4th generation cephalosporins?
Definition
cefepime
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