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Pharmacology Test 3 Drugs Individual
N/A
67
Pharmacology
Undergraduate 4
04/13/2011

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Cards

Term
levodopa
Definition
Parkinsons

dopamine precursor
Term
carbidopa
Definition
Parkinsons

decarboxylase inhibitor (periphery)

*response fluctuations "on-off"
Term
entacapone
Definition
Parkinsons

COMT inhibitor (periphery)
Term
talcapone
Definition
Parkinsons

COMT inhibitor (brain & periphery)
Term
benzotropine
Definition
Parkinsons

(Cogentin)
Term
amantidine
Definition
Parkinsons

(Symmetrel)
Term
rotigotine
Definition
Parkinsons

dopamine agonist
Term
selegiline
Definition
Parkinsons

MAOI (B)
Term
donepezil
Definition
Alzheimers

Ach esterase inhibitor

(Aricept)
Term
rivastigmine
Definition
Alzheimers

Ach esterase inhibitor

(Exelon)
Term
galantamine
Definition
Alzheimers

Ach esterase inhibitor
Term
memantine
Definition
Alzheimers

glutamate NMDA inhibitor (block Ca+ channels)

(Namenda)
Term
baclofen
Definition
ALS/Huntington's

(Lioresal)
Term
chlorpromazine
Definition
Antipsychotic

dopamine (D2) blocker (mesolimbic/mesocortical)

AE: EPRs (parkinson effects) & tardive dyskinesia

(Thorazine)
Term
thiothixene
Definition
Antipsychotic

dopamine (D2) blocker (mesolimbic/mesocortical)

AE: EPRs (parkinson effects) & tardive dyskinesia

(Navane)
Term
haloperidol
Definition
Antipsychotic

dopamine (D2) blocker (mesolimbic/mesocortical)

AE: EPRs (parkinson effects) & tardive dyskinesia

(Haldol)
Term
ziprasidone
Definition
Antipsychotic

serotonin (5HT) blocker

AE: no EPRs, but increases glucose & lipids

(Geodon)
Term
olanzapine
Definition
Antipsychotic

serotonin (5HT) blocker

AE: no EPRs, but increases glucose & lipids

(Zyprexa)
Term
risperidone
Definition
Antipsychotic

serotonin (5HT) blocker

AE: no EPRs, but increases glucose & lipids

(Risperidal)
Term
clozapine
Definition
Antipsychotic

serotonin (5HT) blocker

AE: no EPRs, but increases glucose & lipids

(Clozanil)
Term
aripiprazole
Definition
Antipsychotic

serotonin (5HT) blocker

AE: no EPRs, but increases glucose & lipids

(Abilify)
Term
quetiapine
Definition
Antipsychotic

serotonin (5HT) blocker

AE: no EPRs, but increases glucose & lipids

(Seroquel)
Term
amitriptyline
Definition
Antidepressant

Tricyclic

AE: act on numerous other receptors
Term
nortriptyline
Definition
Antidepressant

Tricyclic

AE: act on numerous other receptors
Term
sertraline
Definition
Antidepressant

SSRI

(Zoloft)
Term
paroxetine
Definition
Antidepressant

SSRI

(Paxil)
Term
escitalopram
Definition
Antidepressant

SSRI

(Lexapro)
Term
fluoxetine
Definition
Antidepressant

SSRI

(Prozac)
Term
venlafaxine
Definition
Antidepressant

SNRI

(Effexor)
Term
phenelzine
Definition
Antidepressant

MAOI

AE: tyramine "cheese" effect causing HTN
Term
trancyclopromine
Definition
Antidepressant

MAOI

AE: tyramine "cheese" effect causing HTN
Term
hydralazine
Definition
Antidepressant

MAOI

AE: tyramine "cheese" effect causing HTN
Term
bupropion
Definition
Antidepressant

(Zyban)
Term
lithium
Definition
Antidepressant

(IP3 hydrolysis)(bipolar disorder)
Term
chlordiazepoxide
Definition
Anti-Anxiety

benzo: bind GABA-a and increase Cl- influx

(Librium)
Term
oxazepam
Definition
Anti-Anxiety

benzo: bind GABA-a and increase Cl- influx

(Serax)
Term
lorazepam
Definition
Anti-Anxiety

benzo: bind GABA-a and increase Cl- influx

(Ativan)
Term
alprazolam
Definition
Anti-Anxiety

benzo: bind GABA-a and increase Cl- influx

(Xanax)
Term
diazepam
Definition
Anti-Anxiety

benzo: bind GABA-a and increase Cl- influx

(Valium)
Term
flumazenil
Definition
tx for benzo overdose
Term
buspirone
Definition
Anti-Anxiety

for chronic anxiety (bc nonsedating/nonaddictive)

(Buspar)
Term
propranolol
Definition
Anti-Anxiety

beta-blocker (stage freight)
Term
ramelteon
Definition
Insomnia

melatonin agonist

(Rozerem)
Term
eszopiclone
Definition
Insomnia

benzo agonist

(Lunesta)
Term
zolpidem
Definition
Insomnia

benzo agonist

(Ambien)
Term
zaleplon
Definition
Insomnia

benzo agonist

(Sonata)
Term
carbamazepine
Definition
Anti-Seizures

Na+ blocker
first line for generalized seizures

AE: aplastic anemia
Term
phenytoin
Definition
Anti-Seizures

Na+ blocker

AE: hirsutism, gingival hyperplasia

*small therapeutic window
Term
lamotrigine
Definition
Anti-Seizures

Na+ blocker
Term
valproic acid
Definition
Anti-Seizures

Ca+ blocker - absence seizures
Term
ethosuximide
Definition
Anti-Seizures

Ca+ blocker - absence seizures
Term
buprenorphine
Definition
PARTIAL opioid agonist (mu)
Term
meperidine
Definition
opioid agonist

AE: respiratory depression
Term
naloxone
Definition
antidote for opioids
Term
naltrexone
Definition
opioid antagonist

(treats addiction)
Term
diclofenac
Definition
NSAID (arthritis)
Term
etodolac
Definition
NSAID (arthritis)
Term
nabumetone
Definition
NSAID (arthritis)
Term
piroxicam
Definition
NSAID (arthritis)
Term
indomethacin
Definition
NSAID (arthritis)
Term
celecoxib
Definition
NSAID (selective for COX-2)

no bleeding risk, but increased chance of stroke/MI
Term
colchicine
Definition
Gout

anti-inflammatory (binds WBCs)
Term
allopurinol
Definition
Gout

xanthine oxidase inhibitor
(xanthine = precursor to uric acid)
Term
probenecid
Definition
Gout

block reabsorption of uric acid
Term
sulfinpyrazone
Definition
Gout

block reabsorption of uric acid
Term
sumatriptan
Definition
Migraine

AE: aterial vasospasm

triptans = serotonin agonists
Term
ergotamine
Definition
Migraine
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