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Pharmacology Test 3
Pharmacology Test 3
25
Pharmacology
Pre-School
02/16/2012

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Term
antibodies
Definition
immunoglobulins; produced by B cell plasma cells in response to a specific protein; react with that protein to cause its destruction directly or through activation of the inflammatory response
Term
antigen
Definition
foreign protein
Term
arachidonic acid
Definition
released from injured cells to stimulate the inflammatory response through activation of various chemical substances
Term
autoimmune disease
Definition
a disorder that occurs when the body responds to specific self-antigens to produce antibodies or cell-mediated responses against its own cells
Term
B cells
Definition
lymphocytes programmed to recognize specific proteins; when activated, these cells cause the production of antibodies to react with that protein
Term
calor
Definition
heat, one of the four cardinal signs of inflammation; caused by activation of the inflammatory response
Term
chemotaxis
Definition
property of drawing neutrophils to an area
Term
complement
Definition
series of cascading proteins that react with the antigen-antibody complex to destroy the protein or stimulate an inflammatory reaction
Term
dolor
Definition
pain, one of the four cardinal signs of inflammation; caused by activation of the inflammatory response
Term
Hageman factor
Definition
first factor activated when a blood vessel or cell is injured; starts the cascading reaction of the clotting factors, activates the conversion of plasminogen to plasmin to dissolve clots, and activates the kinin system responsible for activation of the inflammatory response
Term
interferon
Definition
tissue hormone that is released in response to viral invasion; blocks viral replication
Term
interleukins
Definition
chemicals released by WBCs to communicate with other WBCs and to support the inflammatory and immune reactions
Term
kinin system
Definition
system activated by Hageman factor as part of the inflammatory response; includes bradykinin
Term
leukocytes
Definition
white blood cells; can be neutrophils, basophils, or eosinophils
Term
lymphocytes
Definition
white blood cells with large, varied nuclei; can be T cells or B cells
Term
macrophages
Definition
mature leukocytes that are capable of phagocytizing an antigen (foreign protein); also called monocytes or mononuclear phagocytes
Term
major histocompatibility complex
Definition
the genetic identification code carried on a chromosome; produces several proteins or antigens that allow the body to recognize cells as being self-cells
Term
mast cells
Definition
fixed basophils found in the respiratory and GI tracts and in the skin, which release chemical mediators of the inflammatory and immune responses when they are stimulated by local irritation
Term
myelocytes
Definition
leukocyte-producing cells in the bone marrow that can develop into neutrophils, basophils, eosinophils, monocytes, or macrophages
Term
phagocytes
Definition
neutrophils that are able to engulf and digest foreign material
Term
phagocytosis
Definition
the process of engulfing and digesting foreign pyrogens
Term
pyrogen
Definition
fever-causing substance
Term
rubor
Definition
redness, one of the four cardinal signs of inflammation; caused by activation of the inflammatory response
Term
T cells
Definition
lymphocytes programmed in the thymus gland to recognize self-cells; may be effector T cells, helper T cells or suppressor T cells
Term
tumor
Definition
swelling, one of the four cardinal signs of inflammation; caused by activation of the inflammatory response
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