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Pharmacology Review Marianne
Pharmacology Review Marianne
26
Medical
Graduate
07/19/2015

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Cards

Term
Which herbal affects cytochrome P 450
Definition
St. Johns Wart
Term
Who regulates the herbals on the market
Definition
federal trade commission oversees it but it is not considered medications
Term
Verapmil mechanism of action is
Definition
It decreases dromotropy which means it decreases AV Conduction. Slows the RATE
Term
What is myofascial pain syndrome
Definition
Diagnosis of myofascial pain is made by palpation of trigger points reproducing pain that is characterized as explicitly tender and narrowly localized, aching and lingering associated with stiffness, muscle spasm or muscle weakness as well as some degree of autonomic dysfunction. Trigger point palpation and reproduction of pain is consistently noted in the masseter, levator scapulae, quadratus lumborum, and gluteus medius muscles
Term
if you mix this herbal with a patient on SSRI you risk seroternigic crisis which has sx of?
Definition
ST Johns wart and SSRI can cause a serotonergic crisis
1. tachycardia
2. HTN
3. Agitation
4. Flushing
Term
what drug blocks aldosterone?
Definition
spironolactone
Term
how long
Definition
aldosterone excrtees K and reabsorbs Na. If we block this then we spare K and get rid of Na along with water
Term
myofascial syndrome is most common in what area
Definition
trapezius muscle
Term
what is the concentration effect refer to when uses inhaled anesthetics
Definition
Typically only applies to nitrous. By increasing the pressure of the inspired gas you will result in a hight alveolar concentration.
Term
which inhaled agent has the most metabolites
Definition
sevo (compound A)
Term
which opioid has a myocardial depressant effect
Definition
demerol
Term
how long
Definition
aldosterone excrtees K and reabsorbs Na. If we block this then we spare K and get rid of Na along with water
Term
myofascial syndrome is most common in what area
Definition
trapezius muscle
Term
what is the concentration effect refer to when uses inhaled anesthetics
Definition
Typically only applies to nitrous. By increasing the pressure of the inspired gas you will result in a hight alveolar concentration.
Term
which inhaled agent has the most metabolites
Definition
sevo (compound A)
Term
which opioid has a myocardial depressant effect
Definition
demerol
Term
whats the difference between alfentanil and fentanyl
Definition
alfentinil has a pka of 6.4 which makes a large portion non ionized and readily available. It also is musch less potent than fentanyl. 'combined it causes a much MORE RAPID onset than fentanyl. Alfentinil also has a VOD that is much smaller than fentanyl so its duration is much smaller too. It does have a more strong respiratory depression tho.
Term
do opioids effect vagal tone yes/no
Definition
yes by increasing
Term
what is the pH of thiopental
Definition
9-10.5 = pH of thiopental
Term
precedex works on what receptor
Definition
alpha 2 agonist
Term
clonidine works on what receptor
Definition
alpha 2 agonist
Term
lithium toxcicty
Definition
1. polyuria
2. thrist
3. ataxia
Term
cGMP production does what to smooth muscle
Definition
inhibits calcium entry into the cystol so there is relaxation of the muscle
Term
avoid propanolol in what patient population
Definition
asthmatics since it is not beta 1 selective
Term
name three alpha 1 blockers
Definition
1. tamulosin
2. terazosin
3. prazosin
Term
the core structure of a barbiturate is
Definition
4 carbon atoms and two nitrogen atoms
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