Term
|
Definition
|
Carbamazepine
Oxcarbazepine (4-16 year olds)
Phenytoin
Valproic acid
+Keppra
+Lamotrigine
+Oxcarbazepine
+Gabapentin
|
|
|
Term
Secondarily Generalized Seizure
|
|
Definition
|
Phenytoin
Valproic acid
+ Gabapentin |
|
|
Term
|
Definition
|
Ethosuximide
Valproic acid
+ Benzodiazepams (Clonazepam/Clorazepate) |
|
|
Term
|
Definition
|
Carbamazepine
Phenytoin
Valproic acid
+Lamotrigine |
|
|
Term
Drugs that:
Prolong rate of recovery of voltage gated Na channels. |
|
Definition
- Phenytoin
- Valproic Acid
- Carbamazepine
- Oxcarbazepine
- Lamotrigine
|
|
|
Term
Drugs that:
Inhibit T type Ca channels |
|
Definition
- Ethosuximide
- Valproic Acid
|
|
|
Term
| Drugs that induce CYP3A4 so should not be taken with oral contraceptives? |
|
Definition
- Carbamazepine
- Oxcarbazepine
- Phenytoin
|
|
|
Term
| Drugs that enhance inhibitory GABA |
|
Definition
- Benzodiazepine
- Valproic acid (in vitro)
|
|
|
Term
| What type of seizures can be tested with Kindling? |
|
Definition
|
|
Term
| What type of seizures can be tested with injection of chemoconvulsants? |
|
Definition
|
|
Term
| What induces metabolism of carbamazepine? |
|
Definition
- Phenobarbitol
- Valproic acid
- Itself
|
|
|
Term
| Which drugs activate the 5HT1 receptor? |
|
Definition
- Methysergide maleate
- Ergotamine
- Dihydroergotaline
(The Ergots) |
|
|
Term
| Which drugs act on the 5HT2 receptors? |
|
Definition
- Methysergide maleate (antagonist)
- Amitryptiline (Elavil) (↓ receptors)
|
|
|
Term
| Which migraine drugs are used for acute treatment? |
|
Definition
- Ergotamine
- Dihydroergotamine
- Triptans
- Metoclopramide (choice 2)
- Prochloperazine (choice 2)
- Midrin (moderate migraines)
|
|
|
Term
| Which migraine drugs are used for prophylaxis? |
|
Definition
- Methysergide maleate (choice 2)
- β blockers
- Anti depressents
- AEDs
|
|
|
Term
| Which drugs are dopamine antagonists? |
|
Definition
- Metoclopramide
- Prochlorperazine
|
|
|
Term
| What do μ receptors mediate? |
|
Definition
- Spinal analgesia
- Euphoria
- Addiction
- Respiratory depression
- Sedation
|
|
|
Term
| What do κ receptors mediate? |
|
Definition
- Spinal analgesia
- Sedation
- Meiosis
- Dysphoria
|
|
|
Term
| What drugs can be used to treat opioid addiction? |
|
Definition
- Methadone (Dolophine)
- Buprenorphine (Suboxone)
|
|
|
Term
| Which opioid is commonly used in obsterics? |
|
Definition
|
Causes less respiratory depression in newborns than morphine. |
|
|
Term
| Which opioids are partial agonists at μ receptors? |
|
Definition
- Pentazocin (talwin)
- Butorphanol (Stadol)
- Buprenorphine (Suboxone)
|
|
|
Term
| What are the opioid antagonist drugs? |
|
Definition
- Naloxone
- Naltrexone
- Methylnaltrexone
|
|
|
Term
| Effects of opioids where tolerance occurs |
|
Definition
- Analgesic
- Euphoric sedative
- Respiratory depression
|
|
|
Term
| Effects of opioids where tolerance does not occur |
|
Definition
|
|
Term
| Which opioid is short acting? |
|
Definition
|
|
Term
| Which drugs are used for the acute treatment of gout? |
|
Definition
- NSAIDS
- Corticosteroids (Prednisone)
- Colchicine (2nd choice)
|
|
|
Term
| Which drugs are used as gout prophylaxis? |
|
Definition
- Colchicine (low dose)
- Probenecid
- Allopurinol
- Febuxostat (Uloric) (2nd choice)
|
|
|
Term
| This drug binds to tubulin and inhibits proinflamatory glycoproteins from neutrophils. |
|
Definition
|
|
Term
| This drug inhibits the secretion and reabsorption of organic acids. Net effect ↑ uric acid excretion |
|
Definition
|
|
Term
| This drug inhibits Xanthine Oxidase |
|
Definition
|
|
Term
| This drug inhibits prostaglandin synthesis |
|
Definition
NSAIDS
- Indomethacin
- Ibuprofen
- Ketorolac
|
|
|
Term
| Which NSAID is used as an injection to relieve pain? |
|
Definition
|
|
Term
|
Definition
- Stimulate mucous secretion in upper GI track
- cause platelet agregation (FYI)
(Inhibition is GI irritation) |
|
|
Term
|
Definition
- Inflamation and
- Modulating pain in CNS
- Renal perfusion
- Prostacycline production (FYI)
|
|
|
Term
| What is the only COX2 inhibitor that is still on the market? |
|
Definition
|
|
