Term
| 6 rights of medication administration |
|
Definition
-right drug
-right dose
-right route
-right time
-right patient
-right documentation |
|
|
Term
|
Definition
| impact of the body on drugs |
|
|
Term
| 4 pharmacokinetic processes |
|
Definition
-drug absorption
-drug distribution
-drug metabolism
-drug excretion |
|
|
Term
|
Definition
| Impact of drugs on the body |
|
|
Term
|
Definition
-chemical name
-generic name
-trade name |
|
|
Term
| the average home medicine cabinet contains how many OTC preparations? |
|
Definition
|
|
Term
| with most illnesses, initial therapy consists of |
|
Definition
| self care, self medication with OTC drugs |
|
|
Term
|
Definition
| reduced excretion, increased toxicity |
|
|
Term
|
Definition
| reduced metabolism, increased toxicity |
|
|
Term
| Can pH changes alter the absorption, distribution, metabolism, excretion of a drug? |
|
Definition
|
|
Term
|
Definition
| sudden-onset drug tolerance which is not dose dependent and is difficult to reverse |
|
|
Term
| Pharmacodynamic tolerance |
|
Definition
| the response to the substance is decreased by cellular mechanisms. this may be caused by a down regulation of receptor numbers |
|
|
Term
|
Definition
| reduced sensitivity to a drug that results from the increased ability of the body to metabolize the drug (up-regulation) |
|
|
Term
|
Definition
| Ability of the drug to reach the systemic circulation from its site of administration |
|
|
Term
| Quinidine causes greater QT-interval prolongation in |
|
Definition
|
|
Term
| 3 ways drugs cross a cell membrane |
|
Definition
-channels and pores
-transport systems (p-glycoprotein)
-direct penetration of the membrane |
|
|
Term
|
Definition
| the concentration of a drug is greatly reduced before it reaches the systemic circulation |
|
|
Term
| First pass effect reduces the what of a drug? |
|
Definition
|
|
Term
| Fastest absorption --> slowest absorption |
|
Definition
-liquids, elixirs, syrups
-suspension solution
-powders
-capsules
-tablets
-coated tablets
-enteric coated tablets |
|
|
Term
| True or false: oral drugs have a high first pass effect |
|
Definition
|
|
Term
| areas of rapid distribution |
|
Definition
| heart, liver, kidneys, brain |
|
|
Term
| areas of slow distribution |
|
Definition
|
|
Term
| Which drugs can cross the blood brain barrier? |
|
Definition
| lipid soluble drugs, drugs that have a transport system |
|
|
Term
| drug metabolism usually takes place in |
|
Definition
|
|
Term
| delayed drug metabolism results in |
|
Definition
-accumulation of drugs
-prolonged action of drugs |
|
|
Term
| increased drug metabolism causes |
|
Definition
| -decreased pharmacologic effects |
|
|
Term
| most drug metabolism is performed by which hepatic enzyme system |
|
Definition
|
|
Term
| non-renal routes of drug excretion |
|
Definition
-breast milk
-bile
-lungs
-sweat, saliva |
|
|
Term
|
Definition
| The time it takes for one half of the original amount of a drug in the body to be removed |
|
|
Term
|
Definition
| antacids, antiseptics, saline laxatives, chelating agents, eye drops |
|
|
Term
| milk decreases absorption of |
|
Definition
|
|
Term
| fiber decreases absorption of |
|
Definition
|
|
Term
| high calorie meals increase absorption of |
|
Definition
|
|
Term
| Grapefruit juice has what effect |
|
Definition
-inhibits metabolism of certain drugs
-raises the drugs' blood levels |
|
|
Term
| What drugs' blood levels are raised by grapefruit juice? |
|
Definition
| felodipine, CCB's, lovastatin, cyclosporine,midazolam (Versed) |
|
|
Term
|
Definition
-induces drug metabolizing enzymes
-reduces blood levels of drugs |
|
|
Term
| What is the most common drug that produces a severe allergic reaction? |
|
Definition
|
|
Term
|
Definition
| An uncommon drug response resulting from a genetic predisposition |
|
|
Term
| which trimester has the greatest danger for drug-induced developmental defects/ |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| Total cholesterol should be less than |
|
Definition
|
|
Term
| primary therapy for high cholesterol |
|
Definition
|
|
Term
| What types of drugs treat high cholesterol? |
|
Definition
-HMG coA reductase inhibitors
-bile acid sequestrants
-nicotinic acid
-fibrates |
|
|
Term
|
Definition
|
|
Term
| HMG-CoA Reductase Inhibitors |
|
Definition
|
|
Term
| HMG-CoA Reductase Inhibitors are given |
|
Definition
|
|
Term
| how long does it take for HMG-CoA Reductase Inhibitors to start working? |
|
Definition
|
|
Term
| HMG-CoA Reductase Inhibitors peak |
|
Definition
|
|
Term
|
Definition
| HA, rash, dyspepsia, cramps, gas, constipation, abd pain |
|
|
Term
|
Definition
| hepatotoxicity, myopathy, peripheral neuropathy, linked to parkinson's |
|
|
Term
| Which statin causes rhabdomyolisis |
|
Definition
|
|
Term
| True or False: peripheral neuropathy caused by statins is reversible |
|
Definition
| True, can be reversed with stopping tx |
|
|
Term
| Statins drug interactions |
|
Definition
-other antilipemics (except bile acid sequestrants)
-drugs that inhibit CYP3A4 |
|
|
Term
| Which drugs inhibit CYP3A4? |
|
Definition
| macrolide antibiotics, azole antifungal drugs, HIV protease inhibitors, amiodarone, cyclosporine, grapefruit juice |
|
|
Term
| Can statins be used in pregnancy? |
|
Definition
|
|
Term
| When should statins be taken? |
|
Definition
|
|
Term
| Statins are tough on the liver, so what tests should be done often? |
|
Definition
|
|
Term
|
Definition
-niacin
-niabid
-niaspan
-sloniacin |
|
|
Term
|
Definition
|
|
Term
| How long does it take for nicotinic acid to work? |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Nicotinic acid adverse effects |
|
Definition
| itching, flushing, abd discomfort, hepatotoxicity, hyperglycemia, gouty arthritis, raises homocysteine levels, increased risk for CHD |
|
|
Term
| How can flushing caused by nicotinic acid be pretreated? |
|
Definition
|
|
Term
| Hepatotoxicity occurs most frequently with which type of nicotonic acid? |
|
Definition
|
|
Term
|
Definition
-think "cole"
-cholestyramine
-colestipol
-colesevelam |
|
|
Term
| bile acid sequestrants are given |
|
Definition
|
|
Term
| bile acid sequestrants side effects |
|
Definition
| heartburn, N, belching, bloating, constipation |
|
|
Term
| bile acid sequestrants adverse effects |
|
Definition
| bleeding, HA, tinnitus, burnt odor to urine |
|
|
Term
| Cholesterol absorption inhibitor |
|
Definition
|
|
Term
| ezetimibe (Zetia) is given |
|
Definition
|
|
Term
|
Definition
|
|
Term
| ezetimibe (Zetia) adverse effects |
|
Definition
| myopathy, rhabdomyolisis, hepatitis, pancreatitis, thrombocytopenia |
|
|
Term
| ezetimibe (Zetia) drug interactions |
|
Definition
| statins, fibrates, bile acid sequestrants, cyclosporine |
|
|
Term
| Fibric acid derivatives (fibrates) |
|
Definition
-gemfibrozil
-fenofibrate
-fenofibric acid |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| rashes, GI disturbance, gall stones, myopathy, hepatotoxicity |
|
|
Term
| Fibrates drug interactions |
|
Definition
| displaces warfarin from albumin (test INR) |
|
|
Term
| What types of drugs are used to treat angina? |
|
Definition
-organic nitrates
-beta blockers
-CCB's
-ranolizine |
|
|
Term
|
Definition
-nitroglycerin
-IV morphine
-supplemental O2
-beta blocker
-ACE inhibitor |
|
|
Term
|
Definition
|
|
Term
| How long does it take for nitrates to start working? |
|
Definition
|
|
Term
|
Definition
| HA, tachycardia, postural hypotension, methemoglobin, rash |
|
|
Term
| True or False: HA associated with the use of nitrates diminishes over time |
|
Definition
|
|
Term
| True or False: A tolerance to nitrates can be developed |
|
Definition
|
|
Term
|
Definition
-hypotensive drugs
-PDI-type 5
-BB's, CCB's |
|
|
Term
| Ranolizine has greater benefits in |
|
Definition
|
|
Term
|
Definition
-antiplatelet drugs
-antilipemics
-ACE
-antianginal agents |
|
|
Term
| Ranolazine causes prolonged |
|
Definition
|
|
Term
| Is Ranolazine a first line therapy? |
|
Definition
| NO, it is combined with first line agents if the first line agents do not work alone |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| Vasopressor/dilator prototypes |
|
Definition
dopamine
dobutamine
isoproterenol |
|
|
Term
|
Definition
|
|
Term
|
Definition
"rinone"
-inamrinone
-milrinone |
|
|
Term
|
Definition
|
|
Term
| PDI's take how long to work |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| dysrhythmias, hypotension, N, thrombocytopenia (worrisome!) |
|
|
Term
|
Definition
| ventricular dysrhythmias, hypotension, angina, hypokalemia, tremors, thrombocytopenia |
|
|
Term
|
Definition
-cardiac glycoside antidysrhythmic
-positive inotrope |
|
|
Term
|
Definition
|
|
Term
| PO digoxin takes how long to start working? |
|
Definition
|
|
Term
|
Definition
|
|
Term
| IV digoxin takes how long to start working |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| Force or energy of muscular contractions |
|
|
Term
|
Definition
|
|
Term
|
Definition
| The conduction of electrical impulses |
|
|
Term
| Cardiac glycosides are given |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Therapeutic level of digoxin |
|
Definition
|
|
Term
| What is the relationship between potassium and digoxin? |
|
Definition
| low potassium levels increase dig toxicity and dysrhythmias |
|
|
Term
| What has to be monitored when on dig? |
|
Definition
-electrolyte levels
-drug levels |
|
|
Term
|
Definition
| dysrhythmias- brady or tachy |
|
|
Term
| Digoxin side effects: CNS |
|
Definition
| HA, fatigue, malaise, confusion, convulsions |
|
|
Term
| Digoxin side effects: Eye |
|
Definition
| colored vision (green, yellow, purple), halo vision, flickering light |
|
|
Term
|
Definition
|
|
Term
| What is given to reverse to digoxin toxicity? |
|
Definition
| digoxin immune fab (Digibind) |
|
|
Term
| Digoxin drug interactions |
|
Definition
-diuretic
-ACE inhibitors/ARB's
-sympathomimetics
-quinidine
-verapamil
-amphotericin B
-steroids
-antacids
-some abx |
|
|
Term
|
Definition
| HF, angina, hypertensive crisis |
|
|
Term
| Nitroglycerin side effects |
|
Definition
|
|
Term
| isosorbide dinitrate plus hydralizine side effects |
|
Definition
|
|
Term
| sodium nitroprusside side effects |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
U-upright position
N-nitrates
L-lasix
O-oxygen
A-ACE inhibitors
D-digoxin
F- fluids (decreased)
A- afterload (decreased)
S- sodium restriction
T- test (dig, ABG's, K+ level) |
|
|
Term
|
Definition
|
|
Term
| Thiazide diuretics side effects: CNS |
|
Definition
| HA, dizziness, blurred vision, paresthesias, decreased libido |
|
|
Term
| Thiazide diuretics side effects: GI |
|
Definition
|
|
Term
| Thiazide diuretics side effects: GU |
|
Definition
|
|
Term
| Thiazide diuretics side effects: skin |
|
Definition
| urticaria, photosensitivity |
|
|
Term
| Thiazide diuretics side effects: metabolic |
|
Definition
| hypokalemia, glycosuria, hyperglycemia |
|
|
Term
|
Definition
| immediate mobilization of fluid is necessary |
|
|
Term
| Onset of action of PO lasix |
|
Definition
| 60 min, lasts for 8 hours |
|
|
Term
| With lasix, what should be monitored |
|
Definition
| serum sodium, serum potassium |
|
|
Term
|
Definition
|
|
Term
|
Definition
| dizziness, HA, tinnitus, blurred vision |
|
|
Term
|
Definition
|
|
Term
| Lasix side effects: Hematologic |
|
Definition
| agranulocytosis, neutropenia, thrombocytopenia |
|
|
Term
| Lasix side effects: metabolic |
|
Definition
| hypokalemia, hyperglycemia, hyperuricemia |
|
|
Term
| Potassium-sparing diuretics side effects: CNS |
|
Definition
|
|
Term
| Potassium-sparing diuretics side effects: GI |
|
Definition
|
|
Term
| Potassium-sparing diuretics side effects: other |
|
Definition
urinary frequency, weakness
HYPERKALEMIA |
|
|
Term
| ACE inhibitors help slow down what post-MI |
|
Definition
| left ventricular hypertrophy |
|
|
Term
| ACE inhibitors help prevent renal damage from |
|
Definition
|
|
Term
| ARB's are usually used by patients who cannot tolerate |
|
Definition
|
|
Term
|
Definition
| upper resp infxns, HA, dizziness, insomnia, diarrhea, dyspnea, heartburn, nasal congestion, back pain, fatigue |
|
|
Term
| Is hyperkalemia likely to occur with ARB's? |
|
Definition
|
|
Term
|
Definition
VERY NICE DRUGS
-verapamil
-nifedipine
-dilatizem |
|
|
Term
|
Definition
|
|
Term
|
Definition
| hypotension, bradycardia, A-V block, HA, constipation, N, peripheral edema |
|
|
Term
| Oral CCB's should be taken |
|
Definition
|
|
Term
| Patients should limit their intake of what when on CCB's? |
|
Definition
|
|
Term
| Can CCB extended release forms be crushed or chewed? |
|
Definition
|
|
Term
| Beta-Adrenergic Agonists are |
|
Definition
|
|
Term
|
Definition
"terol"
-albuterol
-salmetrol |
|
|
Term
| albuterol is what type of tx? |
|
Definition
|
|
Term
| Salmetrol is what type of tx? |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Salmetrol onset when treating asthma |
|
Definition
|
|
Term
| Salmetrol onset when treating COPD |
|
Definition
|
|
Term
|
Definition
asthma 2-4 hours
COPD 3-4.5 hours |
|
|
Term
|
Definition
| insomnia, restlessness, tremors, vascular HA, tachycardia, angina (oral), anorexia (oral) |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
-dexamethasone
-fluticasone
-triamcinolone
-beclomethasone |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
-bronchospastic disorders
-control inflammation |
|
|
Term
| Side effects of inhaled corticosteroids |
|
Definition
| pharyngeal irritation, coughing, dry mouth, oral fungal infxns |
|
|
Term
| Leukotriene Receptor Antagonists |
|
Definition
"lukast"
-montelukast
-zafirlukast |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| HA, dizziness, insomnia, N/V, anorexia, liver dysfunction |
|
|
Term
|
Definition
|
|
Term
| Mast cell stabilizers are used to treat |
|
Definition
-chronic asthma
-chronic airway inflammation in allergic asthma |
|
|
Term
| Mast cell stabilizer side effects |
|
Definition
|
|
Term
|
Definition
-fluticasone/salmetrol
-budesonide/formoterol |
|
|
Term
| Glucocorticoid/LABA's are used to treat |
|
Definition
| long term management of asthma |
|
|
Term
| Glucocorticoid/LABA side effects: CNS |
|
Definition
|
|
Term
| Glucocorticoid/LABA side effects: CV |
|
Definition
| increased BP, tachycardia with palpitations, angina |
|
|
Term
| Glucocorticoid/LABA side effects: resp |
|
Definition
| upper resp infxn, throat irritation, hoarseness, voice changes, thrush in mouth/throat, bronchitis, cough |
|
|
Term
| Glucocorticoid/LABA side effects: GI |
|
Definition
|
|
Term
| Glucocorticoid/LABA side effects: immune |
|
Definition
| decreased immune function |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
-asthma
-chronic bronchitis
-emphysema |
|
|
Term
| optimal drug level for "phyllines" |
|
Definition
|
|
Term
|
Definition
|
|
Term
| "phylline" side effects: CV |
|
Definition
| tachycardia, palpitations, ventricular dysrhythmias |
|
|
Term
| "phylline" side effects: GI |
|
Definition
|
|
Term
| "phylline" side effects: GU |
|
Definition
|
|
Term
| "phylline" side effects: endo |
|
Definition
|
|
Term
| signs and symptoms of "phylline" toxicity |
|
Definition
|
|
Term
| First generation anti-histamines are |
|
Definition
|
|
Term
|
Definition
-chlorpheniramine
-diphenhydramine |
|
|
Term
| Second generation antihistamines are |
|
Definition
|
|
Term
| Second-gen antihistamines |
|
Definition
-cetizine
-levocetirizine
-fexofenadine
-loratadine
-desloratadine |
|
|
Term
| Intranasal anti-histamines |
|
Definition
|
|
Term
| True or false: Intranasal anti-histamines are second gen anti-histamines |
|
Definition
|
|
Term
| oral anti-histamine side effects |
|
Definition
| sedation and anti-cholinergic effects |
|
|
Term
| nasal anti-histamine side effects |
|
Definition
|
|
Term
|
Definition
|
|
Term
| glucocorticoids nasal sprays |
|
Definition
-beclomethasone
-budesonide
-ciclesonide
-flunisolide
-fluticasone furoate
-mometasone
-triamcinolone |
|
|
Term
| nasal glucocorticoid side effects |
|
Definition
| nasal irritation, possible slowing of growth in children |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| first-line therapy for allergic rhinitis |
|
Definition
| H1 antagonists, glucocorticoids |
|
|
Term
| Cromolyn is best suited for |
|
Definition
|
|
Term
|
Definition
|
|
Term
| most serious adverse effect of vanco |
|
Definition
|
|
Term
| common adverse effect of vanco |
|
Definition
|
|
Term
| rapid infusion of vanco can cause |
|
Definition
|
|
Term
|
Definition
| flushing, rash, pruritis, urticaria, tachycardia, hypotension |
|
|
Term
|
Definition
| c. diff, infxn with MRSA, treats other organisms for pts allergic to PCN's |
|
|
Term
| Cephalosporins are similar to |
|
Definition
|
|
Term
| True or false: cephalosporins are broad spectrum abx |
|
Definition
|
|
Term
| True or False: cephalosporins are low toxicity |
|
Definition
|
|
Term
| How do cephalosporins change over generation? |
|
Definition
-increased activity against gram neg bacteria
-increased resistance to destruction
-increased ability to reach CSF |
|
|
Term
| most cephalosporins are administered |
|
Definition
|
|
Term
| Why are most cephalosporins administered IV or IM? |
|
Definition
|
|
Term
| Drugs for all types of seizures |
|
Definition
CaPhe
-CArbamazepine
-PHEnytoin/phenobarb |
|
|
Term
| Most frequent adverse effect to cephalosporins |
|
Definition
|
|
Term
| Should patients with severe PCN allergy take cephalosporins? |
|
Definition
|
|
Term
| Can patients with mild PCN allergy use cephalosporins? |
|
Definition
|
|
Term
| How long does it take for IV heparin to start working? |
|
Definition
| works immediately, peaks immediately |
|
|
Term
| How long does it take SQ heparin to start working? |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| how long does is take for lovenox to start working? |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| What other drugs combined with warfarin cause increased bleeding? |
|
Definition
| heparin, aspirin, acetaminophen |
|
|
Term
|
Definition
| direct thrombin inhibitor |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| In addition to bleeding and hemorrhage, dabigatran also causes |
|
Definition
| dyspepsia, nausea, upper abd pain, diarrhea |
|
|
Term
| dabigatran drug interactions |
|
Definition
-rifampin
-keoconazole
-verapamil
-amiodaron
-quinidine
-clarithromycin |
|
|
Term
|
Definition
|
|
Term
| How long does it take aspirin to work? |
|
Definition
|
|
Term
|
Definition
-anti platelet
-anti inflammatory
-analgesic
-anti pyretic |
|
|
Term
| What should be monitored when on aspirin? |
|
Definition
| tinnitus, bleeding, stomach pain, thrombocytopenia |
|
|
Term
| Salicylate poisoning symptoms |
|
Definition
| fever, tinnitus, N/V, lethargy/excitability, hyperventilation, seizures, metabolic acidosis |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| glycoprotein IIb/IIIa Antagonists |
|
Definition
tirofiban
eptifibatide
abciximab |
|
|
Term
| glycoprotein IIb/IIIa antagonists are given |
|
Definition
|
|
Term
| Glycoprotein IIb/IIIa Antagonists onset |
|
Definition
|
|
Term
| tissue plasminogen activators |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| thrombolytics are given when after an "event"? |
|
Definition
|
|
Term
| what labs need to be monitored when using heparin? |
|
Definition
|
|
Term
| What labs need to be monitored when on warfarin? |
|
Definition
|
|
Term
| Warfarin reacts with many |
|
Definition
|
|
Term
| What type of medications may cause bleeding from gums, mucous membranes, nose? |
|
Definition
|
|
Term
|
Definition
| epoetin alfa (procrit, epogen) |
|
|
Term
|
Definition
|
|
Term
| What labs should be monitored when on procrit? |
|
Definition
| CBC w/diff, serum iron, platelets |
|
|
Term
|
Definition
|
|
Term
| Granulocyte Stimulating Colony Factor |
|
Definition
-filgrastim (Neupogen)
-pegfilgrastim (Neulasta) |
|
|
Term
| Granulocyte stim factors adverse effects |
|
Definition
|
|
Term
| granulocyte-macrophage stim factor |
|
Definition
|
|
Term
| sargrastim adverse effects |
|
Definition
| D, weakness, bone pain, leukocytosis, thrombocytosis |
|
|
Term
| Thrombopoietic Growth factor |
|
Definition
| oprelvekin (interluekin II) |
|
|
Term
| interleukin II side effects |
|
Definition
| fluid retention, dysrhythmias, conjuctivitis, visual blurring, papillaedema |
|
|
Term
| True or false: Epoetin alfa, filgrastim, sargramostim, and oprelvekin stimulate proliferation of bone marrow cells |
|
Definition
| True, use w caution for pts with cancers of bone marrow origin |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| pulmonary edema, increased risk for MI or stroke, gastric ulceration, bleeding, renal impairment |
|
|
Term
| True or false: celebrex reacts with warfarin |
|
Definition
|
|
Term
| Can celebrex be used during pregnancy? |
|
Definition
|
|
Term
| adsorbents can cause what side effects |
|
Definition
| costipation, dark stools, twitching, confusion |
|
|
Term
| narrow spectrum penicillinase sensitive |
|
Definition
|
|
Term
| narrow spectrum penicillinase resistant |
|
Definition
methcillin
nafcillin
oxacillin
dicloxacillin |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| PCN combinations are made up of |
|
Definition
| PCN/beta-lactamase inhibitor |
|
|
Term
| cephalosporin drug interactions |
|
Definition
probenecid
alcohol
calcium
ceftriaxone
drugs that promote bleeding |
|
|
Term
| carbapenems can cause drug induced |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| Fosfomycin can treat what in a single dose? |
|
Definition
|
|
Term
| Oral PCN effectiveness is decreased by |
|
Definition
| tomato juice, colas, citrus fruits, fruit juice, caffeine |
|
|
Term
| tetracycline is used to treat |
|
Definition
| chlamydia, gonorrhea, acne |
|
|
Term
| watch for what when on tetracycline |
|
Definition
| D, heartburn, photosensitivity, epigastric discomfort, superinfection, hepatic, renal ototoxicity |
|
|
Term
| what should be avoided when on tetracyclines? |
|
Definition
| milk products, iron preparations, antacids |
|
|
Term
| tetracyclines should be taken with |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| Macrolides adverse effects |
|
Definition
| N/V/D, QT prolongation, sudden cardiac death, superinfection |
|
|
Term
| macrolides should be taken |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| hepatic toxicities, blood dyscrasias, diarrhea, hypersensitivity rxns |
|
|
Term
| Linezolid (abx) side effect |
|
Definition
| N/V/D, HA, myelosupression |
|
|
Term
| linezolid interacts with MAOI |
|
Definition
|
|
Term
| Chloramphenicol (Chloromycetin) |
|
Definition
|
|
Term
| Chloramphenicol is only used for |
|
Definition
| life-threatening infxns where safer drugs cannot be used or did not work |
|
|
Term
| Chloramphenicol adverse effects |
|
Definition
Reversible bone marrow depression
Fatal aplastic anemia
Gray baby syndrome
GI effects
Peripheral neuropathy |
|
|
Term
|
Definition
Gentamicin (Garamycin)
Tobramycin (Nebcin)
Amikacin (Amikin)
Neomycin
Kanamycin (Kantrex)
Streptomycin
Paromomycin |
|
|
Term
| aminoglycosides are used for |
|
Definition
|
|
Term
| aminoglycoside side effects |
|
Definition
| rash, pruritis, urticaria, tremors |
|
|
Term
|
Definition
| peak & trough need to be done |
|
|
Term
|
Definition
|
|
Term
| sulfonamides side effects |
|
Definition
| hemolytic/aplastic anemia, thrombocytopenia, photosensitivity, rash, N/V/D, pancreatitis, convulsions, HA, urticaria |
|
|
Term
| Trimethoprim-Sulfamethoxazole adverse effects |
|
Definition
| N/V, rash, blood dyscrasias, kernicterus, renal damage |
|
|
