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Pharmacology Exam 3
Cardiac Drugs, Oncology drugs, Antiseptics and Disinfectants, Antimicrobials
7
Veterinary Medicine
Professional
11/27/2011
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Term
What are the two main components of blood (arterial) pressure?
 Definition
Cardiac output and systemic vascular resistance
Term
What is the most important job of the CV system?
 Definition
Maintain arterial perfussion pressure as it is the system that delivers nutrients and removes wastes
Term
True/False: We want a large range for the maintainence of BP.
 Definition
FALSE!! Ideally maintained in a very narrow range to balace delivery of nutrients and removal of waste products
Term
What is the path of the RAAS (renin-angiotensin-aldosterone-system) when you have low arterial pressure?
 Definition

Low arterial pressure --> Renin release

Angiotensinogen -(renin acts here)-> Angiotensin I -(ACE acts here)-> Angiotensin II
Term
What are some ways that increasing Ang II increases arterial pressure?
 Definition

1. Direct vasoconstriction

2. Stimulation of drinking

3. Induces release of ADH

4. Stimulates aldosterone secretion

5. Increases urinary retention of sodium and water

6. Also appears to have a central role in chronic regulation of SNS in the medulla

7. Increased sympathetic tone

8. Myocardial hypertrophy and fibrosis
Term
What is the broadest definition of heart failure?
 Definition
Inability of the heart to maintain perfusion pressure
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