Term
| antibacterials antibiotics 4 categories |
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Definition
Penicillins
Cephalosporans
Carbapenums
Monobactams |
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Term
| antibacterials / antibiotics dosage |
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Definition
-dosage may be reduced with renal impairment
-with hemodialysis need more because otherwise it is cleaned out
- use MIC |
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Term
| antibacterials / antibiotics action |
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Definition
***Beta Lactam Ring
-binds with cell membrane of organism.
-cell wall becomes defective
-contents leaks out destroying the pathogen |
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Term
Adverse effects
penicillin (derived from molds and semisynthetic derivatives) |
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Definition
| most common cause of analphylaxis |
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Term
| Penicillin effective against |
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Definition
staph, strep, gonococci, meningococci, treponema pallidum.
More effective with gram positive |
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Term
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Definition
Penicillin G - strep pharyngitis (IV/IM)
Penicillin V - strep pharyngitis (PO)
Oxacillin - MRSA (PO/IV/IM)
Ampicillin - gram +/- (PO/IV/IM)
Amoxicillin - PO only |
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Term
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Definition
1. Unasyn & Augmentum (inactivates the beta lactamase enzyme - resists)
2. Penicillin & Probenecid (increase serum levels and blocks renal excretion) |
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Term
Cephalosporans (derived from fungus)
-four generations
-each generation better than last because activity extended |
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Definition
PO - take with food/milk which delays absorption with little N/V
IV
Surgical prophylaxis 2 hrs before last 4 hrs
ContraI. - analphylactic rxn to penicillin
Target - broad spectrum but better for gram negative.
Not used with MRSA |
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Term
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Definition
Cefazolin 1st
Cefoxitin 2nd
Cefixime 3rd
Cefepime 4th |
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Term
| Cephalosporans: Cefepime 4th |
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Definition
-greater spectrum so used with serious infections
-greater stability and with each successive gen. greater stability /effectiveness |
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Term
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Definition
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