Term
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Definition
Kidneys
GI Tract
Lungs
Sweat and Salivary Glands
Mammary Glands
Hemodialysis |
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Term
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Definition
| unintended, undesirable and often unpredictable |
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Term
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Definition
| Uncommon response due to genetic predisposition |
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Term
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Definition
| Disease produced by medication |
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Term
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Definition
| Medication induced Birth Defect |
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Term
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Definition
| The opposite of what you expect to happen. |
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Term
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Definition
| study the effect of genetics when dealing w/ different classes of meds |
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Term
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Definition
effect a med has on the body
the goal of therapy
a therapeutic response |
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Term
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Definition
| the study of what happens to a drug from the time it is put into the body until it leaves. |
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Term
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Definition
plants (digitalis)
animals/humans (insulin)
minerals (zinc, iron)
synthetic/chemical substances |
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Term
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Definition
Intrathecal(CSF)
Epidural
Intraarticular(synovial fluid)
Intraosseous(bone marrow)
Intraperitoneal or Intrapleural(tumor) |
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Term
| 4 Main Events of Pharmacokinetics |
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Definition
Absorption
Distribution (CO dependent)
Metabolism (Liver)
Excretion |
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Term
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Definition
| only modify or change existing functions |
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Term
| 2 Types of Drug Reservoirs |
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Definition
Plasma Protein Binding
Tissue Binding |
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Term
| Hepatic First Pass Effect |
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Definition
| The way most po meds are circulated through the liver and the microsomal enzymatic action |
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Term
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Definition
| The plasma level concentration compared to the therapeutic effect |
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Term
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Definition
| The ratio b/w the lethal dose and the effective dose. |
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Term
| Factors to consider w/ Adverse Reactions |
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Definition
age
body mass
sex
environment
time of admin(GI free of food)
pathologic state
genetic factors
psychological factors |
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Term
| How is absorption affected w/an increase in adipose tissue? |
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Definition
| Absorption will slow down and can lead to overdose |
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