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Pharmaceutics
Excipients
13
Other
Graduate
10/31/2010

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Cards

Term
Solvents
Definition
Dissolve drugs
ex. Purified Water, Sterile water, alcohol, peanut oil, mineral oil
Term
Vehicles
Definition
Dissolve or disperse drug (carrying agent)
Syrups (sugar solutions), elixers (hydoalcoholic)
Term
Flavors and sweeteners
Definition
Make drug Palatable
Flavors:peppermint, vanillin, cocoa, cinnamon oil
Sweeteners:sucrose, mannitol, sorbitol, glycerin, dextrose
Term
Preservatives:
Definition
Prevent microbial growth
Antifungal:Parabens (methyl, ethyl, butyl), benzoic acid, sodium benzoate.
Antimicrobial:benzalkonium choloride, chlorobutanol, phenol
Term
Stabilizers (antioxidants, chelating agents)
Definition
Prevent decomposition
Antioxidants:ascorbic acid (Vitamin C), sodium ascorbate, sodium metabisulfite.
Chelating agents:Edetic acid, Edate Disodium
Term
Diluents/fillers:
Definition
Increase bulk of formulation
Microcrystalline cellulose, Starch, Lactose, Mannitol
Term
Binders:
Definition
Cause adhesion
Sodium Carboxymethyl Cellulose,ethyl cellulose, gelatin
Term
Disintegrating agents:
Definition
Help break tablet after incubation in water
Microcrystalline cellulose, Starch
Term
Antiadherents/lubricants/glidants"
Definition
Reduce friction during compression, improve flow
Stearates (calcium, magnesium, zinc), Talc
Term
Surfactants:
Definition
help dispersion
Sodium Lauryl Sulfate (SLS)
Term
Ointment bases
Definition
Petrolatum, Polyethylene Gylcol (PEG)
Term
Coating agents
Definition
taste masking,enteric coating (protection)
Sugar coating (liquid glucose, sucrose)
Film coating (ethyl cellulose, methyl cellulose)
Enteric coating (Cellulose Acetate Phthalate, Shellac)
Term
Jonnalagadda
Definition
Too bad he's not Moore...
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