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Pharmaceutics
Dosage Forms and Problems
22
Medical
Graduate
11/16/2010

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Term
Define Solutions (Molecular)
Definition
Solutions are homogeneous liquid preparations containing one or more chemical substances (solutes) dissolved in a solvent or a mixture of solvents.
Term
Define Syrups (Molecular)
Definition
are viscid solutions of sucrose, or some other sugars, thickening agents in water. A nearly saturated solution of sucrose alone in water is known as simple syrup.
Term
Define Elixers (Molecular)
Definition
are sweetened, flavored, hydroalcoholic solutions. Compared to syrups, usually less sweet and less viscous because they contain a lesser amount of sugar.
Term
Define Tinctures (Molecular)
Definition
are alcoholic or hydroalcoholic solutions of either pure chemical substances (e.g., Iodine Tincture) or of plant extracts (e.g., Belladonna Tincture).
Term
Define Spirits (Molecular)
Definition
are alcoholic or hydroalcoholic solutions of volatile substances which often serve as flavoring or medicinal agents.
Term
Define Sols (Colloidal)
Definition
are colloidal dispersions of fine particles in a liquid or gaseous medium. Can be hydrosols or alcosols, depending on the medium (i.e., whether the medium is water or alcohol). Those containing particles in a gaseous medium are called aerosols.
Term
Define Gels (Colloidal)
Definition
are thick preparations of colloidal drugs dispersed in water, forming a gelatinous mixture that maintains the uniformity and stability of the dispersions. Gels can also be defined as semisolid sols.
Term
Define Magmas (Colloidal)
Definition
are flocculated (aggregated) gels. Magmas have variable particle sizes and may be classified as either colloidal or coarse dispersions.
Term
Define Suspension (Coarse)
Definition
are preparations containing undissolved drug particles dispersed in a liquid medium.
Term
Define Emulsion (Coarse)
Definition
liquid preparations containing two immiscible liquids, usually oil and water. o/w or w/o
Term
Define Lotions (Coarse)
Definition
are liquid preparations intended for external application to the skin. They can be suspensions or emulsions of dispersed solid or liquid materials in an aqueous base.
Term
Define Liniments (Coarse)
Definition
are oily type lotions intended for external application to the skin by rubbing
Term
Define Ointments (Coarse)
Definition
are semisolid preparations intended for topical application.
Term
Define Creams (Coarse)
Definition
are generally referred to semisolid emulsions of o/w type. They are a special type of ointment base that are non-greasy and water-washable.
Term
Define Pastes (Coarse)
Definition
are semisolid dosage forms that contain one or more drug substances intended for topical application. Pastes generally contain a higher content of solid materials than ointments and thus are stiffer, less greasy, and more absorptive when used on the skin.
Term
Define Creaming
Definition
Tendency of particles (droplets) to rise up to the surface of the
container (particle < medium, non-redispersible) Occurs in creams, ointments, and emulsions
Term
Define Caking
Definition
Formation of dense, compact sediment at the bottom of the
container (non-redispersible). Occurs in Suspensions and Lotions
Term
Define Coalescense
Definition
Two or more small particles (droplets) fuse to form a single large
particle (surface area of particles decreases, non-redispersible, leads to creaming) Occurs in emulsions
Term
Define Flocculations (Aggregation)
Definition
Small particles clump but do not fuse (surface area unaffected,
weak interaction between particles, reversible) Occurs in colloids
Term
Define Coagulation
Definition
Irreversible clumping of particles (surface area unaffected, strong
interactions between particles) Occurs in Colloids
Term
Define Coacervation (Gelation)
Definition
Phase separation of polymeric dispersions due to restricted
polymeric chain movement (reversible) Iccurs in polymeric colloids
Term
Define Salting Out
Definition
Dehydration and separation of polymeric dispersions due to high
concentrations of added electrolytes or alcohols (reversible) Occurs in polymeric Colloids
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