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Pharm
Final
33
Pharmacology
Graduate
12/01/2011

Additional Pharmacology Flashcards

 


 

Cards

Term
Excitatory neurotransmitters?
Definition
Glutamate
Ach
Term
Inhibitory neurotransmitters?
Definition
GABA
Term
Primary targets for anticonvlsants?
Definition
GABA
y aminobutyric acid
Term
Barbiturate derivative that is metabolized to active metabolites: phenobarbital and phenylethylmalonamide (PEMA)
Definition
Primidone
Term
The bromide loading dose must be what?
Definition
NaBr
Term
Drug of choice to immediately stop seizures?
Definition
Diazepam
Term
Mu agonists (opoids)
Definition
Morphine
Hydromorphone
Fentanyl
Term
Mu partial agonist?
Definition
Buprenorphine
Term
Antidiarrheal?
Definition
Loperamide
Term
Strictly prohibited in female dairy cows >20 months of age?
Definition
Phenylbutazone
Term
Prohibited in all food animals?
Definition
Dipyrone
Term
Only approved NSAID in cats?
Definition
Meloxicam
Term
Prednisolone in?
Prednisone in?
Definition
Cats
Dogs
Term
Reversible inhibition of beta hydroxysteroid dehydrogenase in the adrenal cortex primarily resulting in the inhibition of glucocorticoid synthesis?
Definition
Trilostane
Term
Cytotoxic effects on zona fasiculata?
Definition
Mitotane
Term
Dopamine receptor agonist, suppresses ACTH release from pituitary, mainly used in horses?
Definition
Pergolide
Term
Adverse effects include Nephrotoxicity, pulmonary toxicity in cats
nausea vomiting
minor bone marrow effects
Definition
Cisplatin
Term
Adverse effects of Vincristine
Definition
Vesicant (chemical irritation)
Peripheral neuropathy
Constipation
Minimal myelosuppression (except in p-gp deficient dogs)
Term
Anticancer antibiotic
Definition
Doxorubicin
Term
Doxorubicin adverse effects?
Definition
Vesicant
Myelosuppression
Cardiotoxicity
Arrhythmias
Alopecia
GI
Hypersensitivity
Cats- renal injury
Term
Antineoplastic
Definition
Toceranib
Term
Cyclosporine is a good immuno suppressive drug because of its ability to inhibit T cell activation but is not used a lot because?
Definition
Very expensive
Term
Most relevant p-glycoprotein interactions on inhibition?
Definition
Cyclosporine
Ketoconazole
Term
Alkylating agent that is metabolized to 4-hydroxyphosphamide, acrolein, and phosphoramide mustard?
Definition
Cyclophosphamide
Term
Cyclophosphamide adverse effects?
Definition
Myelosuppression
Sterile hemorrhagic cystitis
GI toxicity
Secondary malignancy
Alopecia
Term
Azathioprine adverse effects
Definition
Myelosuppression
Demodex
GI
Pancreatitis
Cats-profound neutropenia!
Term
Azathioprine has toxicity in what breeds?
Definition
Giant schnauzers
Alaskan Malamutes
Term
May be used for horses with navicular
Definition
Pentoxifylline
Term
Coagulation inhibition is primarily an adverse effect in which inhibition pathway?
Definition
COX-1
Term
COX-1 selective adverse effect?
Definition
Bleeding
Term
COX-2 major adverse effect?
Definition
Clotting
Term
Cushings or hyperadrenocorticism in dogs can be treated with what two drugs?
Definition
Trilostane
Mitotane
Term
Hyperadrenocorticosm in horses can be treated with what drug?
Definition
Pergolide
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