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Pharm
Pharm
18
Pharmacology
Graduate
02/23/2010

Additional Pharmacology Flashcards

 


 

Cards

Term
Blocks sodium dependent membrane choline transporter
Definition
Hemicholiniums
Term
Blocks vesicle associated transporter from transporting acetyle choline from the cytoplasm in exchnage for H (proton)
Definition
Vesamicol
Term
Blocks the release of Acetylcholine from the presynaptic vesicle by  enzymatic  removal of tow amino acids from one or more of the fusion protein (SNAP) (Synaptosomal nerve assocaited protein)
Definition
Botulinum toxin
Term
What drug is responsible for inhibiting the hydroxylation of tyrosine to Dopa?
Definition
Metyrosine
Term
What drug inhibits Dopamine uptake into the secretory vesicle by VMAT(Vesicular Monoamine Transporter)  in exchange for a proton (H)?
Definition
Reserpine Alkaloids
Term

Blocking of NET ( Norepinepherine transporter) increases the transmitter activity in the synpase.

 

 What drugs are responsible for this?

Definition
Cocaine, tricylic antidepressant drugs
Term
name drugs capable of releasing stored transmitter from  noradrenergic nerve endings by a calcium independent porceess
Definition
Tyramine, amphetamine, ephedrine
Term
Name drug that inhibits monoamine oxidase and have other effects that result in increased norepinepherine activity in the synapse
Definition
amphetamines
Term
What can cause the release of transmitter from NANC (nonadrenegeric noncholinergic nerurons)?
Definition
Capsaicin, a neurotoxin derived from chili peppers
Term
methyldopa which is converted to α methylnorpeinepherine works by working on what and not by  replacing norepinephrine in storage vesicle?
Definition
central α adrenoreceptors
Term
Clonidine works by stimulating
Definition
α adrenoreptors in arteriols
Term
Clonidine work on ____>_____
Definition
aplha 2 >alpha 1
Term
Methyldopa, clonidine, guanabenz, guanfacine are all drugs that
Definition
reduce hypertenion by working on the vasomotor center
Term
What is used to treat pre-clampsia?
Definition
Methyldopa
Term
Guanethidine, guanadrel, and reserpine works where?
Definition
symphathetic nerve terminals
Term
what drugs enters the nerve terminals via NET1 and replaces norepinepherine within the vesicles?
Definition
guanethidine
Term
Name 2 beta blockers that are cardioselective
Definition
metoprolol & atenolol
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