Term
Aspirin
Pharmacologic Class
Therapeutic Class |
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Definition
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Term
Aspirin
How does it act as a blood thinner? |
|
Definition
| Decreases platelet "stickyness" |
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Term
|
Definition
| Tinnitus, vertigo, headache, confusion, drowsiness, diaphroesis, hyperventilation, vomiting, diarrhea, acid-base & electrolyte disturbance, hyperthermia |
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Term
Aspirin
With or without food? |
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Definition
| with food, milk, antacid, or large glass of water to reduce GI symptoms |
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Term
indomethacin (Indocin)
Therapeutic class |
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Definition
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Term
indomethacin (Indocin)
Indications |
|
Definition
| Arthritis (osteo, gouty, or rheumatoid) |
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Term
|
Definition
narcotic agonist
(centrally acting analgesic) |
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Term
acetaminophen (Tylenol)
Class |
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Definition
| antipyretic non-opioid analgesic |
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Term
acetaminophen (Tylenol)
Damages what organ? |
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Definition
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Term
acetaminophen (Tylenol)
Anticdote |
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Definition
| acetylcysteine (Acetadote) |
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Term
acetaminophen (Tylenol)
S+Sx of overdose |
|
Definition
| Nausea, vomiting, anorexia, abdominal pain, confusion, jaundice |
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Term
tramadol (Ultram)
Indications |
|
Definition
| Moderate to moderately severe pain |
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Term
celecoxib (Celebrex)
Pharm Class
Ther Class |
|
Definition
Cox 2 inhibitor
antirheumatics
NSAID |
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Term
celecoxib (Celebrex)
Indications |
|
Definition
|
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Term
celecoxib (Celebrex)
Action |
|
Definition
| Inhibits enzyme COX-2 that is required for prostaglandin synthesis |
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Term
hydroxychloroquine (Plaquenil)
Class |
|
Definition
Antimalarial
Antirheumatic |
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Term
hydroxychloroquine (Plaquenil)
Indications |
|
Definition
Malaria
Severe rheumatoid arthritis
Systemic lupus erythematosus |
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Term
hydroxychloroquine (Plaquenil)
With or without food? |
|
Definition
| With meals to minimize GI distress |
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Term
hydroxychloroquine (Plaquenil)
Requires concurrent monitoring by what kind of doctor? |
|
Definition
| eye exams every 3-6months |
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Term
methotrexate (Rheumatrex)
Ther Class |
|
Definition
antirheumatics
immunosuppressants
antineoplastics |
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Term
methotrexate (Rheumatrex)
Indications |
|
Definition
Cancer
Severe psoriasis
Rheumatoid arthritis |
|
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Term
methotrexate (Rheumatrex)
Damages what organs? |
|
Definition
|
|
Term
methotrexate (Rheumatrex)
Side effects |
|
Definition
Immunosuppression
Bone marrow suppression
Hair loss
photosensitivity
increased bleeding times
Stomatitis
GI Symptoms |
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Term
methotrexate (Rheumatrex)
Overdose treatment |
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Definition
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Term
etanercept (Enbrel)
Ther. Class
Pharm Class. |
|
Definition
antirheumatics
anti TNF agents (tumor necrosis factor) |
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Term
etanercept (Enbrel)
How does it work? |
|
Definition
| binds to TNF, making it inactive. TNF is a mediator of inflammatory response. |
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Term
etanercept (Enbrel)
Indications |
|
Definition
| Decrease progression of rheumatoid arthritis |
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Term
etanercept (Enbrel)
main side effect |
|
Definition
|
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Term
infliximab (Remicade)
Ther Class
Pharm Class |
|
Definition
antirheumatics
GI anti inflammatories
anti TNF agents (tumor necrosis factor) |
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Term
infliximab (Remicade)
Indications |
|
Definition
Rheumatoid arthritis
Crohn's disease
psoriatic arthritis
Ulcerative colitis
Plaque psoriasis |
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|
Term
infliximab (Remicade)
Action |
|
Definition
| Neutralizes and prevents the activity of TNF resulting in anti-inflammatory and antiproliferative activity |
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Term
infliximab (Remicade)
main side effect |
|
Definition
|
|
Term
|
Definition
| anti inflammatories steroidal |
|
|
Term
|
Definition
chronic diseases including:
Inflammatory
Allergic
Hematologic
Neoplasmic
Autoimmune |
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Term
|
Definition
| Suppresses inflammation & normal immune response |
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Term
prednisone
side effects to appearance |
|
Definition
| cushingoid appearance (moon face, buffalo humb) |
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Term
|
Definition
immunosuppression
hyperglycemia
weight gain |
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|
Term
prednisone
With or without food? |
|
Definition
|
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Term
capsacian (Zostrix)
Ther Class |
|
Definition
|
|
Term
capsacian (Zostrix)
Action |
|
Definition
| binds to nociceptors in the skin, causing neuronal excitation. With repeated use, desensitation occurs |
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Term
capsacian (Zostrix)
Indications |
|
Definition
|
|
Term
|
Definition
|
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Term
|
Definition
| Prophylaxis and treatment of acute attacks of gouty arthritis |
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|
Term
|
Definition
| Interferes with the functions of WBC in initiating and perpetuating the inflammatory response to monosodium urate crystals |
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Term
|
Definition
| grapefruit and grapefruit juice |
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Term
probenecid (Benemid)
Ther Class |
|
Definition
|
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Term
probenecid (Benemid)
Indications |
|
Definition
| Prevention of gouty arthritis (DOESN'T TREAT ACUTE ATTACKS) |
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Term
probenecid (Benemid)
Action |
|
Definition
| Inhibits renal tubular reabsorbtion of uric acid (thus promoting excretion) |
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Term
probenecid (Benemid)
what should not be taken concurrently? |
|
Definition
| Aspirin or other salicylates |
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Term
allopurinol (Zyloprim)
Ther Class
Pharm Class |
|
Definition
antigout agent
antihyperuricemic
xanthine oxidase inhibitor |
|
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Term
allopurinol (Zyloprim)
Indications |
|
Definition
| Prevention of attach of gouty arthritis and nephropathy |
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Term
allopurinol (Zyloprim)
Action |
|
Definition
| Inhibits production of uric acid |
|
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Term
allopurinol (Zyloprim)
hard on what organ? |
|
Definition
|
|
Term
allopurinol (Zyloprim)
dietary restrictions |
|
Definition
Possibly alkaline diet
Avoid alcohol |
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