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Pharm Test
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76
Pharmacology
Graduate
03/05/2012

Additional Pharmacology Flashcards

 


 

Cards

Term
Bethanecol (urecholine)
Definition
Muscarinic agonist over nicotinic agonist
stimulates GI motility
contracts bladder
Term
Pilocarpine
Definition
muscarinic agonist
induces vomiting
treates glaucoma
contracts ciliary muscle contraction
Term
Atropine
Definition
Muscarinic antagonist, alkaloid
preanesthetic, decreases respiratory secretion
treats vagal hyperactivity, decreases gastric motility, causes hypohidrosis, decreases lacrimation, xerostomia (dry mouth), myadrysis, urinary retention
Term
Pienzepine
Definition
M1 antagonist, treats ulcers
Term
methacholine
Definition
cholinergic agonistcauses vasodilation, treats ergot poisoning
Term
carbachol
Definition
cholinergic agonist, treat colic and impaction
Term
muscarine
Definition
muscarinic agonist
Term
arecoline
Definition
muscarinic agonist
decrease heart rate and blood pressure
may cause dyspnea-bronchoconstriction
Term
Physostigmine
Definition
Reversible, cholinesterase inhibitor
causes miosis and decreases intraocular pressure, treats non-obstructive atony
Term
Neostigmine
Definition
Reversible, cholinesterase inhibitor
Term
Edrophonium
Definition
Reversible, cholinesterase inhibitor
Term
organophosphates
Definition
irreversible cholinesterase inhibitor
Term
Pralidoxime
Definition
reactivates cholinesterase
Term
DFP-diisopropyl phosphofluridate
Definition
organphosphate
Term
tetraethyl-phosphate (TEPP)
Definition
organphosphate
Term
parathion
Definition
organphosphate
Term
malathion
Definition
organphosphate
Term
ronnel
Definition
organphosphate
Term
soman
Definition
organphosphate
Term
sarin
Definition
organphosphate
Term
scopolamine
Definition
muscarinic antagonist, alkaloid
Term
hyoscyamine
Definition
muscarinic antagonist, alkaloid
Term
glycopyrrolate
Definition
muscarinic antagonist, used s a preanesthetic, does not cause tachycardia, reduces gastric and respiratory secretions, lasts longer than atropine
Term
Homatropine
Definition
similar to atropine, shorter duration, fewer GI, CV side effects
Term
fenoldopam
Definition
D1 adrenergic receptor, improves tissue perfusion
partial agonist/antagonist
catecholamine
Term
Dobutamine
Definition
B1 adrenergic agonist, dilates peripheral blood vessels, improves cardiac contractility, catecholamine
Term
Dopamine
Definition
D1, D2 agonist, improves renal bloodflow, increase cardiac contractility, catecholamine
Term
ephedrine
Definition
adrenergic agonist, CNS stimulant, respiratory stimulant, reverse barbituate, noncatecholamine
Term
phenylephrine
Definition
non-cholaminergic agent, adrenergic agonist, nasal spray, decrease bleeding from surgical procedures
Term
phenylpropanolamine
Definition
non catecholamine, adrenergic agonist, causes weight reduction, treats urinary incontinence in dogs,
Term
pseudoephedrine
Definition
non catecholamine, alpha and beta adrenergic agonist,
Term
Clenbuterol
Definition
B2 agonist, used to treat COPD
Term
ergot alkaloid
Definition
adrenergic antagonist
Term
pheochromocytomas
Definition
synthetic adrenergic antagonist, treats visceral ischemia due to circulatory shock
Term
phenoxybenzamine
Definition
synthetic adrenergic antagonist, treats visceral ischemia due to circulatory shock
Term
prazosin
Definition
alpha 1 adrenergic antagonist
Term
Yohimbine
Definition
alpha 2 adrenergic antagonist, reverse anesthesia in large wild animals
Term
Propranolol
Definition
beta adrenergic antagonist, treats atrial fibrillation or flutter
Term
nadolol
Definition
beta adrenergic antagonist, treats atrial fibrillation or flutter
Term
timolol
Definition
beta adrenergic antagonist, treats atrial fibrillation or flutter
Term
Reserpine
Definition
prevent NE release, treats hypertension
Term
6-OH dopamine
Definition
depletes NE
Term
Alpha methyl paratyrosine
Definition
blocks tyrosine hydroxylase, inhibits NE synthesis
Term
Selegeline (L-deprenyl)
Definition
used for parkinson's, improve mood, mental health, increase catecholamine and serotonin in the brain
Term
Salicylate or carboxylic acid
Definition
NSAIDs, suppresses inflammation, prevent making arachidonic acid
Term
indoles
Definition
NSAIDs suppresses inflammation, prevent making arachidonic acid
Term
propionic acid
Definition
NSAIDs, suppresses inflammation, prevent making arachidonic acid
Term
fenamates
Definition
NSAIDs, suppresses inflammation, prevent making arachidonic acid
Term
oxicams
Definition
NSAIDs, suppresses inflammation, prevent making arachidonic acid may cause chronic renal failure, inhibits COX1 and 2,
Term
pyrazolones
Definition
NSAIDs, suppresses inflammation, prevent making arachidonic acid
Term
acetyl salicilic acid
Definition
NSAID, inhibits COX, stabilizes lysosomes, inhibits formation of kinins, antithrombotics,
Term
phenylbutazone
Definition
NSAID, small therapeutic index, treats arthritis, spondylitis, and laminitis
Term
Flunixin Meglumine (banamine)
Definition
NSAID, nicotinic acid derivative, analgesic, treats visceral pain, acute cow mastitis
Term
Naproxen
Definition
NSAID, treats soft tissue infflamation, large margin of safety
Term
Carprofen (rimadyl)
Definition
NSAID, targets COX-2 only so limited gastric injury, postoperative analgesic, good for osteoarthritis, can affect cartilage formation
Term
Ibuprofen
Definition
NSAID, reversibly binds COX, causes gastric lesions
Term
meclofenamic acid
Definition
NSAID, slow onset of action, treats laminitis
Term
Ketoprofen
Definition
NSAID, inhibits COX, LO and bradykinin
Term
piroxicam
Definition
NSAID, osteoarthritis in dogs,
Term
Orgotein
Definition
NSAID, treats osteoarthritis
Term
polysulfated glycoaminoglycan
Definition
chondroprotetctive, proteolytic enzymes are inhibited, lysosomes are stabilized
Term
Tepoxalin (zubrin)
Definition
dual pathway NSAID, blocks COX and lipoxygenase, decreases gastric irritation and ulceration, metabolized to its active form tepoxalin pyrazole acid, treats osteoarthritis
Term
firocoxib, deracoxib
Definition
NSAID, specific COX2 inhibitor
Term
Hyaluronic acid
Definition
lubricant in synovial fluid, inhibits phagocytosis and lymphocyte migration
Term
dimethyl sulfoxide (DMSO)
Definition
scavenges free radicals, useful for CNS inflammation, inhibits platelet aggregation, treats acute swelling, acute ofr chronic otitis, skin wounds, acral lick dermatitis
Term
hydrocortisone
Definition
steroidal anti-inflammatory, found in creams and ointments
Term
cortisone
Definition
steroidal anti-inflammatory, converts to cortisol by the liver
Term
prednisone
Definition
steroidal anti-inflammatory, converted by the liver into prednisolone, little to no mineralcorticoid effect
Term
prednisolone
Definition
steroidal anti-inflammatory, used if liver is non-functional, little to no mineralcorticoid effect
Term
methyprednisolone
Definition
steroidal anti-inflammatory, little to no mineralcorticoid effect
Term
isoflupredone or 9-flouroprednisolone
Definition
high power steroidal anti-inflammatory, used in large animals
Term
triamcinalone
Definition
intermediate power steroidal anti-inflammatory,not ideal for alternate day therapy
Term
Betamethasone
Definition
long acting steroidal anti-inflammatory, no mineralcorticoid effect, used more commonly in large animals due to cost and availability issues
Term
Dexamethasone
Definition
long acting steroidal anti-inflammatory, no mineralcorticoid effect, used more commonly in large animals due to
Term
Flumethasone
Definition
long acting steroidal anti-inflammatory, no mineralcorticoid effect, used more commonly in large animals due to
Term
Cocaine
Definition
is a helluva drug
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