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Pharm - Telavacin/Aminoglycosides
PA School
9
Pharmacology
Graduate
02/13/2010

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Cards

Term
indications for TElavancin:
Definition
1. MRSA
2. VISA
3. daptomycin/linezolid (R) S. aureus
Term
Telavancin dose:
Definition
10mg/kg QD over 60min
Term
dose adjustment required for telavancin in:
Definition
renally impaired
Term
indications for aminoglycosides:
Definition
EFFECTIVELY Tx G- INFECTIONS
Term
explain the combo therapy of aminoglycosides:
Definition
with serious infections (ex. endocarditis) B-lactams are given with aminoglycosides; the BL help the aminoglycosides to enter the cell
Term
2 aminoglycosides:
Definition
1. Gentamycin
2. Tobramycin
Term
aminoglycosides spectrum of activity:
Definition
1. G+ (w BL combo)
2. G-
3.
Term
Therapeutic Drug levels of aminoglycosides and ADRs:
Definition
Peak: MDD 4-10, ODD 16-24
Trough: <1mg/L
can lead to ototoxicity/renal toxicity
Term
when should aminoglycoside peaks be drawn?
Definition
30-60min after injection/infusion
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