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Pharm II Test 4 - Comprehensive
Winter Semester 2011
171
Medical
Graduate
05/10/2011

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Cards

Term
Which drug can cause SE including restlessness, irritability, insomnia, difficulty concentrating, dry mouth, anorexia, tachycardia, increased BP, N/V and death?
Definition
Ephedra
Term
What type of med is MgOh?
Definition
antacid
Term
What type of med is AlOH?
Definition
antacid
Term
What type of med is CaCO3?
Definition
Antacid
Term
What type of med is MgOh/AlOH?
Definition
antacid
Term
What med is used as an OTC herbal treatment for depression? What prescription drug is it similar to?
Definition
St. John's Wart; Similar to SSRIs
Term
What is the OTC treatment of choice for acne?
Definition
Benzyl Peroxide
Term
What should you avoid before going to bed for good sleep hygeine?
Definition
AVOID exercise, caffeine, lg meals, alcohol, and nicotine
Term
What OTC drug can be used in the treatment of osteoarthritis and possibly TMJ arthritis?
Definition
glucosamine
Term
What is the max time after intercourse that Plan B can be used effectively?
Definition
72hrs (Repeated 12hrs later)
Term
Besides being an (unapproved) wt loss agent, what can ephedra be used as?
Definition
nasal decongestant
Term
Which meds are OTC examples of salicylic acid?
Definition
Clearasil
Stri-dex
Term
Which med after long-term use can lead to constipation/impaction or hypophosphatemia?
Definition
AIOH
Term
What type of agent is coal tar?
Definition
antiseborrheal agents
Term
What type of agent is ketoconazole?
Definition
antiseborrheal agent
Term
What type of agent is pyrtithione zinc (head and shoulders)?
Definition
antiseborrheal agent
Term
What type of agent is selenium sulfide (selsun blue)?
Definition
antiseborrheal agent
Term
What is diphenhydramine (sominex, tylenol PM) used for?
Definition
sleep aid
Term
What is doxylamine (unisom) used for?
Definition
sleep aid
Term
Which antacid is less likely to cause constipation or diarrhea and offers high neutralizing capacity?
Definition
MgOH/AlOH combo med
Term
What effect does guanifenacin have?
Definition
protussive/expectorants
Term
What type of skin findings are contraindicated for use with salicylate?
Definition
abraded, sunburned or damaged skin
Term
With what med is salicylate use contraindicated in?
Definition
anticoagulant
Term
In which condition is salicylate use contraindicated in?
Definition
asthmatics
Term
Which antihistamines cause CNS depression and therefore can be used as sleep aids?
Definition
Diphenhydramine
Doxylamine
Term
Which sedating antihistamine is preferred for rhinorrhea in pregnancy?
Definition
Chlorpheniramine
Term
How much 1 ephedra with caffeine increase you HR?
Definition
15 bpm
Term
What med can increase the risk of BPH?
Definition
Antihistamine
Term
What med can cause interstitial nephritis?
Definition
analgesics
Term
Which antihistamine is the least sedating?
Definition
Lortadine
Term
How long do the effects of cromolyn take to be apparent? When is the max benefit seen?
Definition
3 - 7 days to take effect
2-4 weeks for MAX benefit
Term
What OTC med has been shown in clinical trials to reduce HA and nausea in migraine pts?
Definition
feverfew
Term
What OTC med potentiates the effects of ethanol and other CNS depressants?
Definition
Kava
Term
What OTC med potentiates the effects of ethanol and other CNS depressants?
Definition
Kava
Term
What OTC herbal can be used in the treatment atherosclerosis, colorectal CA, Gastric CA, HTN, tick bites, tinea infections and hyperlipidemia (although its effects are controversial in this condition)?
Definition
Garlic
Term
What is the max dose of acetaminophen?
Definition
4000mg/day
Term
What OTC med can cause sedation and drowsiness?
Definition
antihistamines
Term
What type of med is Ibuprofen?
Definition
NSAID
Term
What type of med is Ketoprofen?
Definition
NSAID
Term
What type of med is Naproxen?
Definition
NSAID
Term
What OTC med is used in the treatment of DM type 2 and Respiratory Tract infections?
Definition
American Ginseng
Term
In the US do herbal product have to be pure? Does safety have to be demonstrated?
Definition
NO; Safety does NOT have to be demonstrated
Term
Which type of diabetes DHEA used to treat?
Definition
DM
Term
Which two meds increase systolic and diastolic BP, HR, cardiac contractility, peripheral vasoconstriction, bronchodilation, and CNS stimulation?
Definition
Epinephrine and Pseudoepinephrine
Term
How long may it take to see the results from rogaine?
Definition
4 months
Term
What is sulcrafate used for?
Definition
mucosal protective agent
Term
What are prostaglandin analogs used for?
Definition
mucosal protective agents
Term
What is dextromethorphan (vicks, benylin) used for?
Definition
antitussives/cough suppressants
Term
What is codeine (guiatuss AC, mytuss AC) used for?
Definition
antitussive/cough suppressants
Term
What is topical ointment/lozanges/patches (camphor or menthol) used for?
Definition
antitussives/cough suppresants
Term
What OTC med can cause AE including gastric pain, N/D, chills, alopecia and edema?
Definition
Chondroitin
Term
What is cromolyn used for?
Definition
Nasal product to treat seasonal allergic rhinitis
Term
What OTC can be used to treat sneezing?
Definition
antihistamines
Term
What med has a cross-sensitivity with shellfish?
Definition
glucosamine
Term
What is levonorgesterol 0.75mg used for?
Definition
emergency contraception (plan B) option
Term
What is DHEA most effective in?
Definition
SLE
Term
Which OTC agents can lead to hepatotoxicity, GI bleed and tinnitus?
Definition
ASA and NSAIDs
Term
What med works by chemicals interfering with the neuronal uptake of amine neurotransmitters similar to tricyclics or SSRIs?
Definition
St. John's Wart
Term
What OTC med has been shown to be effective in osteoarthritis?
Definition
chondroiton
Term
What med can cause 'rebound' HA?
Definition
analgesics containing caffeine
Term
What specific SSRI does St. John's wart MOST resemble?
Definition
Fluoxetine
Term
Which med is a non-selective beta and alpha receptor agonist that directly and indirectly stimulates the sympathetic NS?
Definition
Ephedra
Term
Which meds are used to treat non-ulcer dyspepsia and prevention of bleeding from gastritis?
Definition
H2 antagonists
Term
What is butoconazole used for? What is its OTC name?
Definition
yeast infections (mycelex-3)
Term
What is tioconazole used for? What is its OTC name?
Definition
yeast infections (monistat and vagistat)
Term
What med increases the risk for CA and cardiovascular morbidity in post-menopausal women, when at high levels?
Definition
DHEA
Term
What OTC med is effective in treating herpes simplex 2 and the common cold?
Definition
siberian ginseng
Term
What OTC med interacts with CNS stimulants, drugs that prolong the QT interval (Digoxin) and theophylline?
Definition
Ephedra
Term
What med can cause cardiac problems and can cause severe asthma problems with chronic use?
Definition
Primatene Mist
Term
What med when use is abused, can lead to abdominal cramping, fluid loss or electrolyte imbalances?
Definition
laxatives
Term
Which med is contraindicated for use in children, pregnant women, lactating mothers and should not be taken in the oral form?
Definition
Ephedra
Term
What med in high doses can cause sudden death due to cardiac arrhythmias?
Definition
Ephedra
Term
Which 3 antihistamines are NON-sedating?
Definition
Lortadine
Ceftirazine
Fexofenadine
Term
What type of med is cimetidine?
Definition
H2 antagonist
Term
What type of med is famotidine?
Definition
H2 Antagonist
Term
What type of med is Nizatadine?
Definition
H2 antagonist
Term
What type of med is rantidine?
Definition
H2 antagonists
Term
What OTC herbal when applied topically may cause severe skin irritation?
Definition
Garlic
Term
What OTC med come from tanacetum parthenium?
Definition
feverfew
Term
Which antibiotics are typically used in the treatment of acne?
Definition
Clindamycin
Erythromycin
Metronidazole
Sodium Sulfacetamine
Term
Which meds can interact with coumadin and increase INR?
Definition
ASA and NSAIDs
Term
What med has an adverse effect of exfoliation of the palms of the hands and the soles of the feet?
Definition
Kava
Term
What is metoclopramide used for?
Definition
constipation
Term
What are calcium channel activators used for?
Definition
constipation
Term
What is the most sedating antihistamine used for rhinorrhea?
Definition
diphenhydramine
Term
What med works by fostering cell turnover and desquamation breaking up hardened areas of skin?
Definition
keratolytic
Term
What OTC med is used in the illegal production of meth?
Definition
pseudoephedrine
Term
What's the max time for sleep aid use without evaluation?
Definition
2 weeks b/c underlying insomnia may be occurring
Term
What meds are included in Pepcid Complete?
Definition
H2 blocker + antacid (CaCO3) + MgOH
Term
When may immunostimulatory effects decline w/ echinacea?
Definition
> 8 weeks
Term
What OTC med is used to treat chronic constipation and IBD?
Definition
tegaserod (Zelnorm)
Term
What is the amount of time you should use PPIs and H2 blockers?
Definition
> 2 weeks
Term
Who are PPIs and H2 blockers not recommended in?
Definition
children < 12 y/o
Term
What med can be used to help with jet lag?
Definition
melatonin
Term
Which OTC meds can cause increased risk of hepatotoxicity and GI bleed? (4)
Definition
ASA
Salicylates
Acetaminophen
NSAIDs
Term
What do analgesics/allergy/cough/cold preparations contain?
Definition
sympathomimetics
Term
In what pts should analgesics/allergy/cough/cold preparations be avoided in?
Definition
Avoided in HTN, Angina and Hyperthyroidism
Term
What med can be relieve allergic rhinitis symptoms, but isn't effective against a runny nose not caused by allergies?
Definition
Antihistamines
Term
Which meds cause increased gastrin secretion which increases proliferation rates of colonic mucosa potentially promoting carcinogenesis?
Definition
PPIs
Term
What med can be used to open clogged pores?
Definition
comedolytic
Term
What med is a pediculocide?
Definition
permethrin
Term
What OTC med has an anxiolytic effect that takes approximately 4 - 8 weeks of tx?
Definition
Kava
Term
Which med should not be used in a pt with active PUD, certain platelet disorders and pts taking oral anticoagulants?
Definition
ASA and NSAIDs
Term
Which med is used to treat IBS w/constipation in women > 18y/o and the elderly?
Definition
Lubiprostone
Term
What OTC med is used to treat the common cold and vaginal candidiasis?
Definition
Echinacea
Term
What med can cause rebound congestion?
Definition
Afrin
Term
What may exacerbate disease sensitivities to adrenergic stimulation like HTN, hyperthyroid, DM, ischemic HD, elevated IOP and BPH?
Definition
Decongestants
Term
What OTC med can be used to improve cognitive function, and has been used to treat type 2 DM, ED and premature ejaculations?
Definition
panax ginseng
Term
What meds can cause insomnia, nervousness, and restlessness?
Definition
sympathomimetics or caffeine
Term
What med is a rubefacient that produces vasodilation of cutaneous vasculature producing reactive hyperemia?
Definition
Salicylate
Term
What can decongestant nasal sprays > 3 days cause?
Definition
Rebound Congestion
Term
What meds are used to treat a sore throat?
Definition
Benzocaine, dyclonine (sucret's, cepacol)
Term
What med is a PPI?
Definition
omeprazole (prilosec)
Term
What med is bactericidal, is used in acne and can bleach hair/clothing?
Definition
Benzoyl Peroxide
Term
What med causes the release of NE from sympathetic nerve endings?
Definition
Ephedra
Term
What med has AE including insomnia, vivid dreams, anxiety/agitation/irritability, GI discomfort, fatigue, dry mouth, HA/photosensitivity and decreased libido?
Definition
St. John's Wort
Term
Which 3 meds concentrations in the blood are increased due to cimetidine's inhibition of drug metabolism?
Definition
Phenytoin
Theophylline
Warfarin
Term
What med has AE including breath/body odor, heartburn/gas, N/V/D, increased risk of bleeding and allergic rxtn?
Definition
Garlic
Term
What is an extract from the plant of the genus Ephedra?
Definition
Ma-huang
Term
What med is used as a hair growth stimulant?
Definition
minoxidil (rogaine)
Term
What meds are used to treat or prevent chronic constipation?
Definition
Osmotic laxatives (MgOH, sorbitol, lactulose)
Term
What is oxymetazoline used for?
Definition
topical decongestants
Term
What is phenylephrine caused by?
Definition
topical decongestants
Term
What is xylometazoline used for?
Definition
topical decongestants
Term
What med causes androgenic SE due to the formation of testosterone including acne and hirsutism when used in premenopausal women?
Definition
DHEA
Term
What OTC treatment can be used to tx dryness, itchy, and nosebleeds?
Definition
Nasal Saline
Term
What OTC med can be used in the treatment of circadian rhythm sleep disorders, and sleep-wake cycle disturbances?
Definition
Melatonin
Term
What is the antidote for CCB or fluoride antidote?
Definition
Calcium
Term
Who are we cautious with when we use bicarb, sodium to reverse membrane-depressant cardiotoxic drugs?
Definition
Heart failure to avoid sodium overload
Term
What is the antidote for cyanide?
Definition
Hydroxocobalmin
Term
What is the antidote for carbon monoxide?
Definition
Oxygen
Term
What med can increase bronchial secretions, seizures and bradycardia?
Definition
Physostigmine
Term
What is the antidote for organophosphates and carbamates?
Definition
atropine
Term
What is the antidote for BB?
Definition
Glucagon
Term
In what time frame does Acetylcysteine have the best results?
Definition
given within 8 - 10 hrs
Term
Who do we avoid flumazenil in?
Definition
Seizures
BZD dependance
Tricyclic OD
Term
How often is pralidoxime repeated in organophosphatase cholinesterase inhibitor OD?
Definition
Every 3 - 4 hrs
Term
What is the max dose of flumaxenil?
Definition
3mg
Term
When should digoxin antibodies used as an antidote?
Definition
With serious arrhythmias and hyperkalemia
Term
What type of OD should the use of physotigmine be avoided in?
Definition
tricyclic anti-depressant OD
Term
What is the antidote for theophylline, caffeine and metaproterenol?
Definition
Esmolol
Term
What med is used as an antidote for membrane-depressant cardiotoxic drugs like tricyclics and quinidine?
Definition
Bicarb and Na
Term
What med has symptoms including tachycardia, dilated pupils and ileus?
Definition
atropine
Term
What is the antidote for organophosphate cholinesterase? In which med is it NOT beneficial for?
Definition
Pralidoxime; Carbamate
Term
How many mg of iron are binded by 100mgs of deferoxamine?
Definition
8.5mgs of iron
Term
What is the antidote of iron salt?
Definition
deferoxamine
Term
With what meds are larger doses of naloxone needed?
Definition
Propoxyphene
Codeine
Fentanyl
Term
What are the two types of acetylcysteine and how are they delivered?
Definition
acetadote - IV
Mucomyst - Orally
Term
When should ethanol therapy be started?
Definition
before lab dx is confirmed
Term
What dose of bicarb, sodium usually recerses cardiotoxic effects?
Definition
1-2 mEq/kg IV bolus
Term
What is the antidote for acetaminophen?
Definition
Acetylcysteine
Term
What antidote is more convenient for methanol and ethylene glycol?
Definition
fomepizole
Term
What is the antidote for digoxin and related cardiac glycosides?
Definition
Digoxin antibodies
Term
What is the antidote for methanol and ethylene glycol?
Definition
ethanol or fomepizole (more convenient)
Term
What is the antidote for narcotic drugs and other opioid derivatives?
Definition
Nalaxone
Term
How much digoxin does one vial of digoxin antibodies bind?
Definition
0.5 mg
Term
What is the antidote suggested for antimuscarinic anticholinergic agents? What is it NOT used for?
Definition
Physostigmine; Tricyclic anti-depressants
Term
How many mg IV bolus of glucagon may reverse hypotension & bradycardia associated w/ BB OD?
Definition
5 - 10
Term
What med has SE including altered mental status, depression and confusion?
Definition
H2 antagonists
Term
What class of drugs has very similar SE to anticholinergics?
Definition
Anti-depressants (tricyclics)
Term
Which class of drugs has SE including bleeding and enhanced drug interaction complications?
Definition
Anti-coagulants
Term
What class of med has SE including electrolyte imbalance, dehydration, urinary incontinence, hypotension and altered mental status?
Definition
diuretics
Term
What med has SE including dry mouth and sedation?
Definition
Antihistamines
Term
What class of drugs has SE including excessive sedation, gait disturbances, delirium and depression?
Definition
Sedatives/hypnotics
Term
What drug's SEs are gastric irritation, GI bleed, constipation, renal dysfunction, fluid retention and altered mental status?
Definition
NSAIDs
Term
What class of drug has SE including dry mouth, constipation, urinary retention, delerium, cognitive impairment and aggravation of glaucoma?
Definition
anticholinergics
Term
What med has AE including ototoxicity and renal dysfunction?
Definition
Aminoglycosides
Term
What drug has SE including N/V, cardiac arrhythmias, altered mental status and yellow vision?
Definition
Digoxin
Term
What class of drugs has SE including sedation, impaired motor function, depression and altered mental status?
Definition
BZDs
Term
What drug's SE include dry mouth, constipation, urinary retention, tachycardia, hypotension, sedation and cognitive impairment?
Definition
Anti-depressants (tricyclics)
Term
What med has SE including constipation, sedation and altered mental status?
Definition
Narcotic analgesics
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