Term
| Which seizure med is indicated as a first line for Partial Seizures? |
|
Definition
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|
Term
| Which seizure meds are indicated for partial seizures as 2nd line therapy? (4 - TLGP) |
|
Definition
Tigabine
Levetiracetam
Gabapentin
Pregabaline |
|
|
Term
| Which seizure drugs are indicated for Tonic/Clonic Seizures? (4 - PPCT) |
|
Definition
Phenytoin
Primidone
Carbamazepine
Topiramate |
|
|
Term
| Which seizure drug is indicated for post-traumatic seizures? |
|
Definition
|
|
Term
Which seizure drug is indicated for Status Epilepticus (short-term administration)?
Which seizure drug is indicated for Status Epilepticus (refractory)? |
|
Definition
Fosphenytoin
Phenobarbital |
|
|
Term
| Which seizure med is indicated for Absence Seizures? |
|
Definition
|
|
Term
| Which seizure meds are indicated for myoclonic seizures? |
|
Definition
Ethosuximide
Levetiracetam (adjunt) |
|
|
Term
| Which seizure meds are used to treat Lennox-Gastaut? |
|
Definition
Felbamate
Rufinamide (adjunct) |
|
|
Term
| Which seizure med is used to treat atonic seizures? |
|
Definition
|
|
Term
| Which seizure med is used to treat convulsive seizures? |
|
Definition
|
|
Term
| Which seizure med is the drug of choice for neonatal seizures? |
|
Definition
|
|
Term
| Which seizure med is 1st line treatment for Primarily Generalized seizures? Which seizure med is used in adjunct to treat primarily generalized seizures? |
|
Definition
Valproic Acid
Levetiracetam |
|
|
Term
| Which seizure med is used to treat Partial seizure and convulsive seizure in pts as young as 4y/o? |
|
Definition
|
|
Term
| Which seizure med is indicated for psychomotor seizures? |
|
Definition
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|
Term
| Which seizure med is used to treat focalepileptic seizurs? |
|
Definition
|
|
Term
| Which seizure med is indicated for infantile spasms? |
|
Definition
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|
Term
| Which seizure drug is contraindicated in pts with Sulfa med allergies? |
|
Definition
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|
Term
| Which seizure med is a powerful inducer of meds that go through the CYP-450 system? |
|
Definition
|
|
Term
| Which seizure med decreases the efficacy of OCs? |
|
Definition
|
|
Term
| Which seizure med has major GI concerns? |
|
Definition
|
|
Term
| Which seizure meds is contraindicated for pts who have HLA-B 1502? |
|
Definition
|
|
Term
| Which 2 seizure meds have a SE of gum hypertrophy/gingival? |
|
Definition
| Ethosuximide and Phenytoin |
|
|
Term
| Which 2 seizure meds have a SE of peripheral neuropathy? |
|
Definition
|
|
Term
| Which seizure med has a SE of hirsuitism? |
|
Definition
|
|
Term
| Which 2 seizure meds can cause osteomalacia and folate deficiency? |
|
Definition
|
|
Term
| Which seizure med can cause Hydantoin facies (enlarged nose)? |
|
Definition
|
|
Term
| Which seizure med has a combo of SE including vasodilation, hypotension and paresthesia? |
|
Definition
|
|
Term
| Which 2 seizure meds can lead to hyponatremia? |
|
Definition
| Carbamazepine & Oxycarbazepine |
|
|
Term
| Which seizure med can lead to the development of SIADH and water intoxication? |
|
Definition
|
|
Term
| Which seizure med has a combination of SE including Peripheral neuropathy, Gingival hyperplasia, Hirsuitism, Osteomalacia, Folate deficiency, and Hydantoin facies? |
|
Definition
|
|
Term
| Which seizure med has a combination of SE including diplopia, ataxia, Hyponatremia (leading to SIADH and Water Intox), Osteomalacia and Folate Defeciency? |
|
Definition
|
|
Term
| Which 3 seizure meds have a SE of a rash? |
|
Definition
| Ethosuximide, Lamotrigine, Phenobarbital |
|
|
Term
| Which seizure med has a combination of SE including GI upset, CNS depression, Rash, Weight loss, and Gum Hypertrophy? |
|
Definition
|
|
Term
| Which seizure med has a combo of SE including HA, Anorexia and Weight loss? |
|
Definition
|
|
Term
| Which seizure med is used to treat Partial Seizures (Refractory), Lennox-Gastaut, and Atonic seizures BUT cannot be used in children under 14y/o? |
|
Definition
|
|
Term
| Which second line seizure med for partial seizures cannot be used in children 3 - 12 y/o? |
|
Definition
|
|
Term
| Which seizure med has a combo of SE including dizziness, ataxia and peripheral edema? |
|
Definition
|
|
Term
| Which seizure med is induced by OCs? |
|
Definition
|
|
Term
| Which seizure med has a combo of SE including rash, somnolence, dizziness and diplopia? |
|
Definition
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|
Term
| Which seizure med has a combo of SE including nervousness, tremors, dizziness and depression? |
|
Definition
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|
Term
| Which seizure med used as 2nd line for partial seizures has no known drug interactions? |
|
Definition
|
|
Term
| Which seizure med has a combo of SE including peripheral edema, weight gain, dizziness and somnolence? |
|
Definition
|
|
Term
| Which seizure med has a SE of a Polycystic Ovary-like syndrome? |
|
Definition
|
|
Term
| Which seizure med has a SE of porphyria? |
|
Definition
|
|
Term
| Which 2 seizure meds have a SE of sedation? How can this be surmounted? |
|
Definition
Phenobarbital and Levetiracetam
Dose at night to prevent daytime sedation |
|
|
Term
| What is a common unwanted effect of all anti-convulsant meds? |
|
Definition
|
|
Term
| Which seizure med has a SE profile including Sedation, depression, paradoxical hyperactivity, porphyria and rash? |
|
Definition
|
|
Term
| Which seizure med has a SE of psychomotor slowing and cognitive dysfunction as well as ataxia and weight loss? |
|
Definition
|
|
Term
| Which seizure med has a SE profile including N/V and Polycystic ovary-like syndrome? |
|
Definition
|
|
Term
| Which seizure med has a SE of word-finding difficulties? |
|
Definition
|
|
Term
| Which seizure med has a SE profile including Irritability, coordination difficulties and sedation? |
|
Definition
|
|
Term
| Which seizure med has a SE profile of Diplopia and Lack of Coordination, as well as N/V and Dizziness? |
|
Definition
|
|
Term
| Which seizure med has a SE profile of somnolence, dizziness and ataxia? |
|
Definition
|
|
Term
| Which seizure med has a SE profile of ataxia and vertigo? |
|
Definition
|
|
Term
| Which seizure med has a SE profile of somnelence, weight gain, edema, anemia and peripheral neuropathy? |
|
Definition
|
|
Term
| Which seizure meds can lead to Steven Johnson's syndrome? (4 - CELP) |
|
Definition
Carbamazepine
Ethosuximide
Lamotrigine
Phenytoin |
|
|
Term
| Which seizure med can lead to the development of SLE? |
|
Definition
|
|
Term
| Which 2 seizure meds can lead to Aplastic Anemia? What must be done to monitor these patients? |
|
Definition
Carbamazepine & Felbamate
Monthly CBC to monitor aplastic anemia |
|
|
Term
| Which seizure med has a category B black box warning for its possibility of causing fetal hydantoin syndrome? |
|
Definition
|
|
Term
| Which 2 seizure meds are Schedule V controlled substances? |
|
Definition
| Phenobarbital and Pregabaline |
|
|
Term
| Which seizure med can lead to delayed intellectual development? |
|
Definition
|
|
Term
| Which seizure med can lead to metabolic acidosis? |
|
Definition
|
|
Term
| Which 2 seizure meds can lead to neprolithiasis? |
|
Definition
|
|
Term
| Which seizure med can lead to Acute Angle Glaucoma? |
|
Definition
|
|
Term
| Which seizure med can lead to pancreatitis? |
|
Definition
|
|
Term
| Which seizure med can lead to Thrombocytopenia? |
|
Definition
|
|
Term
| Which seizure med can lead to Oligohydrosis? |
|
Definition
|
|
Term
| Which seizure drug can lead to Leukopenia? |
|
Definition
|
|
Term
| Which seizure med can lead to shortening of QT interval? |
|
Definition
|
|
Term
| Which seizure med can lead to Megaloblastic anemia and Agranulocytosis? |
|
Definition
|
|
Term
| Which seizure med can lead to vision loss? |
|
Definition
|
|
Term
| Which seizure med can lead to MRI signal changes in the brain? |
|
Definition
|
|
Term
| Which 5 factors are considered when choosing a seizure med to prescribe? (TMDDC) |
|
Definition
Tolerability
Monitoring
Drug Interactions
Dosing Frequency
Combination Therapy |
|
|
Term
| With which seizure meds should renal function be monitored? (PGLOTZ) |
|
Definition
Phenobarbital
Gabapentin
Levetiracetam
Oxycarbazepine
Topiramate
Zonisamide |
|
|
Term
| With which seizure meds must hepatic function be monitored? (CLOT VZP) |
|
Definition
Carbamazepine
Lamotrigine
Oxycarbazepine
Tigabine
Valproic Acid
Zonisamide
Phenytoin |
|
|
Term
| With which seizure meds should the therapeutic levels be monitored? (CPVP) |
|
Definition
Carbazepine
Phenobarbital
Valproic Acid
Phenytoin |
|
|
Term
| With which seizure med should blood dyscrasia be monitored? |
|
Definition
|
|
Term
| When is a women's highest vulnerability to seizures? |
|
Definition
| Before and during menses and at the time of ovulation |
|
|
Term
| What is the effect of estrogen on seizures? |
|
Definition
| Seizure-activating effect - Inhibits GABA receptors, potentiates glutamate activity |
|
|
Term
| What is the effect of progesterone on seizures? |
|
Definition
| Seizure-protective effects - Increase GABA activity and reduces neuronal d/c rates |
|
|
Term
| Which two seizure meds have teratogenic effect? How must they be monitored? |
|
Definition
Valproic Acid & Carbamazepine
Must monitor Folic Acid levels |
|
|
Term
| What are some likely complications during pregnancy for individual with seizures or on seizure meds? |
|
Definition
Increased maternal seizures
Increased pregnancy Complications (including spontaneous abortion) |
|
|
Term
| What are the requirements for possible withdrawl from seizure medication? |
|
Definition
1 - Seizure free for 2 - 4 yrs
2 - Complete seizure control w/in 1 yr of onset
3 - Seizure onset btwn age 2 and 35 y/o
4 - Neurologic Exam and EEG WNL |
|
|
Term
| How should seizure meds be withdrawn and what are the risks with withdrawl of meds? |
|
Definition
Meds should be withdrawn gradually
Risk of status epilepticus and recurrence of seizures |
|
|
Term
| How should seizure meds be withdrawn and what are the risks with withdrawl of meds? |
|
Definition
Meds should be withdrawn gradually
Risk of status epilepticus and recurrence of seizures |
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