Term
| originally designed for Gi & Gu infections: |
|
Definition
| Fluoroquinolones; commonly used in respiratory and Gu infections |
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Term
| Are fluoroquinalones good for MRSA? |
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Definition
|
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Term
| spectrum of activity for fluoroquinalones: |
|
Definition
1. G+
2. G-
3. Anaerobes (moxifloxacin only)
4. Atypicals |
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Term
| fluoroquinalones: concentration or time dependant killing? |
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Definition
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Term
| fluoroquinalones contraindicated in:why? |
|
Definition
1. pregnancy
2. Children <19
cartilage destruction
3. Elderly (dizziness/falls) |
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|
Term
| describe GI absrption of fluoroquinalones: |
|
Definition
| Great absorption; equivalent doses for IV and Oral |
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|
Term
| list locations of good/bad tissue penetration of fluoroquinalones: |
|
Definition
Good: resp, GI, GU, GB
Bad: BBB |
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Term
Drug Interaction that decrease fluoroquinalone absorption to <5%:
ISCAMZ |
|
Definition
1. Iron
2. Sucrafate
3. Ca++
4. Al
5. Mg
6. Zn
5. |
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Term
| 3 major adverse affects of fluorquinalones: |
|
Definition
1. hypo/hyperglycemia
2. dizziness
3. phototoxicity |
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Term
|
Definition
1. Ciprofloxacin
2. Levo...
3. Moxi...
4. Gemi... |
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Term
| 2 G+ that fluorquinalones work esp well on: |
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Definition
|
|
Term
| which fluoro doesn't get into urine? |
|
Definition
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Term
| fluoro for uncomplicated UTI: |
|
Definition
| cipro & levo 250-500mg BID |
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