Term
| treatment of benign prostate hypertrophy |
|
Definition
saw palmetto
(flomax is Rx- targets alpha 1 receptor on prostate) |
|
|
Term
|
Definition
increased cerebral bloodflow
-alzheimers, memory improvement |
|
|
Term
|
Definition
antianxiety agent (mood improvement)
anticonvulsant
can produce oral numbness |
|
|
Term
|
Definition
topically to treat ciriasis, burns
internally produces explosive laxative effect |
|
|
Term
| common adverse effect of herbal |
|
Definition
inhibit platelet aggregation
increased bleeding |
|
|
Term
|
Definition
immune system booster
-could counteract when on autoimmune drugs, i.e. if being treated for lupus |
|
|
Term
|
Definition
digestive aid
lowering cholesterol
decreased lipids (hyperlipidemia)
--ve
increased bleeding
allergic resp, skin rxns |
|
|
Term
|
Definition
smooth muscle
endothelium
brain |
|
|
Term
|
Definition
gastric mucosa
cardiac muscle
mast cells
brain |
|
|
Term
|
Definition
diphenhydramine, dimenhydrenate
-anti-allergic, sedatative effect, motion sickness, mild anesthetic effect |
|
|
Term
| most sedative H1 blockers |
|
Definition
diphenhydramine and dimenhydrinate
(benadryl, dramamine)
-highly anti-cholinergic
-treatment of early parkinson tremors |
|
|
Term
|
Definition
a ethylenediamine
less anti ACH than diphenhydramine
-used mainly as sleeping aid |
|
|
Term
|
Definition
| sometimes preferred over diphenhydramine, produces less sedation |
|
|
Term
|
Definition
component of OTC cold drugs
low sedation antihstamine |
|
|
Term
|
Definition
anti-emetic (including the result of drugs)
can produce parkinsons symptoms/disease |
|
|
Term
| excess can produce torsades des pointes |
|
Definition
terfenadine (Seldane)
astemizole (Hismanal) |
|
|
Term
| problems of broad spectrum Abs |
|
Definition
GI
diarrhea
superinfections
-c.dificile --> pseudomembranous colitis
-candida overgrowths --> yeast infections |
|
|
Term
| narrow spectrum penicillins |
|
Definition
pen v, pen g
GRAM ++ aerobic |
|
|
Term
|
Definition
combination of amoxicillan and clavulanic acid
-designed to resist penicillanse producing bact. (staph) |
|
|
Term
| common bacteria of bacterial endocarditis |
|
Definition
| alpha-hemolytic streptococci |
|
|
Term
| interactions can be worsened b/w clarith/eryth and drugs by... |
|
Definition
|
|
Term
| Ab that chelates divalent, trivalent ions |
|
Definition
tetracyclines
-impairs its absorption
-shouldn't be taken with milk, antacids |
|
|
Term
| very broad Ab that can be Rx'd for dental related infections |
|
Definition
|
|
Term
| breastfeeding women and tetracyclines |
|
Definition
| probable that it chelates in milk, and isn't absorbed by children |
|
|
Term
|
Definition
tetracyclines
ciprofloxacin |
|
|
Term
| chronic persistent bone infections |
|
Definition
|
|
Term
| penicillin alternative for odontogenic infection |
|
Definition
|
|
Term
| dental Ab most associated with c. dificile colitis |
|
Definition
symptoms are diarrhea
CLINDAMYCIN |
|
|
Term
| predisposing factors of c.dificile colitis |
|
Definition
broad spectrums
diuretics
H2 blockers
diabetes
age |
|
|
Term
| 2 -cidal Ab combined to both disrupt cell walls and DNA synth |
|
Definition
penicillin V
metronidazole |
|
|
Term
| metronidazole interactions |
|
Definition
warfarin
antibuse rxns
lithium (not as bad as NSAIDS though) |
|
|
Term
|
Definition
photosensitivity
tendon damage, rupture
nausea/diarrhea
increased THEOPHYLLINE |
|
|
Term
|
Definition
prosthetic cardiac valve
previous endocarditis
certain CHDs
-cyanotic CHD
-congenital defect 6 months after surgery
transplant recipients WITH VALVE PROBLEMS |
|
|
Term
|
Definition
amoxicillin 2 grams, hour before
clindamycin 600 mg
azith/clarith 500 mg |
|
|
Term
| disrupts fungal RNA and protein synthesis |
|
Definition
|
|
Term
| antifungal for dermatological infections of skin/scalp/nails, disrupts mitotic spindle |
|
Definition
|
|
Term
|
Definition
|
|
Term
| antifungal drugs have increased recently.. |
|
Definition
| more hiv/aids pts. = opportunistic infections |
|
|
Term
| oral and GI fungal infections, with low toxicity when given this route |
|
Definition
| amphotericin B (fungizone) |
|
|
Term
| major problem/toxicity of amphotericin |
|
Definition
liver toxicity, nephrotoxicity
-pts. should have creatinine clearance done first |
|
|
Term
| a antifungal given for serious infections, which has toxicity of bone marrow suppression |
|
Definition
|
|
Term
| unique feature of griseofulvin |
|
Definition
should be take with fatty meal...
most other drugs fat impairs absorption |
|
|
Term
| drugs which prefer acid environment |
|
Definition
azole antifungals
-ketocanazole
-itraconzole
-flucanazole
-clotrimazole |
|
|
Term
| antifungal which can decrease M/F adrenal hormones |
|
Definition
ketocanazole
-gynecomastia in men |
|
|
Term
| azole with prominent CNS penetration |
|
Definition
|
|
Term
|
Definition
|
|
Term
| inhibits the integration of viral RNA into host DNA |
|
Definition
|
|
Term
|
Definition
| a neuraminidase inhibitor |
|
|
