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Pharm Exam I
Ahhhh.
23
Pharmacology
Undergraduate 2
02/06/2012

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Cards

Term
Neuromuscular blocking agents block??
Definition
Nicotinic-M receptors at the NMJ
Term
How do NM blocking agents cause relaxation?
Definition
they prevent ACh from activating nicotinic M receptors on skeletal muscles
Term
What route(s) are NM blockers given?
Definition
IV only
Term
What is the prototype for NM non-depolarizing blockers?
Definition
tubocurarine (curare)
Term
Prototype for NM depolarizing blockers?
Definition
Succinylcholine (Anectine)
Term
Adverse effects of tubocurarine?
Definition
Hypotension, respiratory depression, bradycardia, dysrhythmias, cardiac arrest
Term
Alpha-agonist adrenergic prototype?
Definition
phenylephrine
Term
Beta 1 & beta 2 adrenergic agonist prototype?
Definition
Isoproterenol
Term
SELECTIVE beta 1 adrenergic agonist prototype?
Definition
Doubutamine
Term
SELECTIVE beta 2 adrenergic agonist prototype?
Definition
Albuterol
Term
What are the medicinal uses for cocaine?
Definition
Stopping nose bleeds through vasoconstriction
local anesthesia
Term
Alpha, Beta 1, Beta 2 adrenergic agonists are all stimulated by what hormone?
Definition
Epi
Term
Alpha, beta 1 adrenergic agonists are stimulated by what hormone?
Definition
NE
Term
Affect of alpha adrenergic agonist receptor on the eye?
Definition
Dilation of pupil
Term
Affect of alpha adrenergic agonist on arterioles?
Definition
Constriction of arterioles out in the periphery as a mechanism of controlling BP
Term
Affect of alpha adrenergic agonist on mucus & lacrimal glands?
Definition
Vasoconstriction, decreased secretions. stops a runny nose.
Term
Affect of beta-1 adrenergic agonist on the heart?
Definition
INCREASED:
SA node firing
automaticity
AV node conduction velocity
contractility
Term
Affect of beta-1 adrenergic agonist on the kidney?
Definition
Vasoconstriction
Term
Affect of beta-2 adrenergic agonist on airway smooth muscle?
Definition
Relaxation
Term
Affect of beta-2 adrenergic agonist on large arterioles & veins?
Definition
relaxation
Term
Affect of beta-2 adrenergic agonist on liver & fat cells?
Definition
Release of glucose
& release of lipids into the bloodstream.
Term
Affect of beta-2 adrenergic agonist on B cells of the pancreas?
Definition
Increase insulin release
Term
Affect of beta-2 adrenergic agonist on the uterus?
Definition
Relaxation
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