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Pharm Equations
Fun Equations
14
Medical
Graduate
05/28/2009

Additional Medical Flashcards

 


 

Cards

Term
Henderson-Hasselbach Eqn
Definition

pKa = pH - log (A-)/(HA)

Or: B/HB+

Term
Volume of Distribution
Definition
VD=Amount in Body/Plasma [Conc]
Term
Loading Dose
Definition

Loading Dose = VD* CpE

CpE = Effective Plasma [Conc]

Term
Maintenance Dose
Definition

Maintenance Dose = VD (CpE - CpM)

Volume of Dist * (Effective [Plasma] - Min [Plasma])

Term
Steady State Plasma Conc
Definition
Cpss = Infusion Rate (mg/hr) / Clearence of Total Body (mg/hr)
Term
Renal Clearence
Definition
Clr = [conc] Urine/Plasma * Collection volume/time
Term
Total Body Clearence
Definition
Cltb = VD * KE
Term
First-order rate constant
Definition
KE = 0.693/(t1/2)
Term
Liver Extraction Ratio
Definition

Liver Extaction Ratio = (Ca - Cv)/Ca

Conc that enters - conc that leaves liver over conc that enters

Term
Bioavailability
Definition

Bioavailability = AUCoral / AUCiv

Area Under Curve

Term
Time to 99%
Definition
t99 = 3.3 * t1/2
Term
Time to 50%
Definition
One half life?
Term
Theraputic Index
Definition
TI = LD50 / ED50
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