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pharm drug interactions for final
pharm drug interactions for final
21
Dentistry
Undergraduate 3
11/19/2014

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Cards

Term
PDE's (for erectile dysfunction) ( Viagra/cialis/levitra) should be cautioned with what medication
Definition
PDE should not be used while on cardiac meds such as nitroglycerine, nitrates, grapefruit juice
Term
erythromycin and tetracycline have what effect on digitalis
Definition
erythromycin and tetracycline increase effects of digitalis(slow pulse)
Term
when should epi not be used
Definition
epi should not be used on cardiac patiens, non selective beta blockers, and tricyclic antidepressents
Term
tegretal should not be used with what heart medication
Definition
tegretol causes toxicity when paired with calcium channel blockers
Term
antibiotics may decrease what 2 things?
Definition

antibiotics interfere with oral contraceptives

 

also interfere with vitamin K and clotting so do not take ANTICOAGULANT with antibiotic!!!!

Term
what is contraindicated for asthma patients
Definition
NSAIDS and sulfa drugs are contraindicated for asthma patients
Term
a patient taking oral contraceptives should avoid
Definition
PCN, Tetracyline, acetaminophen (causes liver stress), and benzodiazepines (increased clearance)
Term
never give tylenol to what patient
Definition
never give tylenol to a patient with kidney disease
Term
macrolides cause toxicity with what drugs
Definition

macrolides cause toxicity with:

 

theophyline

 

digoxin

 

warfarin

 

cyclosporine

Term
ace inhibitors reduce effects of what drug
Definition
ace inhibitors reduce effects of NSAIDS
Term
what is the relationship of psychotheraputic drugs like phenothiazines (thorazine, thioridazine (mellaril)) and opiods?
Definition
phenothiazines potentiate opiods
Term
what effect does epinephrine have on phenothiazines>
Definition
epi makes bp drop when on phenothiazines
Term
what drug causes toxicity when combined with lithium?
Definition
naproxin and NSAID causes toxicity with lithium
Term
what interacts with sulfonylureas (an anti diabetic drug) producing a decrease in blood sugar and affects brittle diabetics.
Definition
aspirin interacts with sulfonylureas
Term
what happens when NSAIDS interact with Alpha adrenergic agents?
Definition
NSAIDS reduce the antihypertensive effects of the alpha adrenergic agent.
Term
what happens when antibiotics are taken with warfarin?
Definition
antibiotics increase (potentiate) the effects of warfarin and interfere with normal flora that interferes with vitamin K and clotting mechanisms
Term
what are the effects when NSAIDS are taken with thiazides (diuretic)?
Definition
NSAIDS reduce bad effects of thiazides (reduce low potassium effects)
Term
this drug is known to lower triglycerides and is sometimes used in combination with statin drugs
Definition
niacin-nictinic acid / VIT B-3
Term
what drugs interfere with vit B-6
Definition
TB meds cyclosporin, estrogen, steroids
Term
grapefruit juice and versed (a benzodiazepine)
Definition

grapefruit juice and versed =increased sedation and hypnotic effects

 

the same effect is seen with grapefruit juice and halcion another benzodiazepine

Term
alpha adrenergic beta blockers + epi=
Definition
reflex tachycardia and severe hypotension
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