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Pharm - Antibiotic Intro - test 1
a
90
Pharmacology
Undergraduate 2
09/14/2011

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Term
Bactericidal
Definition
Kills the bacteria
Term
Bacteriostatic
Definition
Slow the growth of bacteria allowing body to fight
Term
Culture and sensitivity
Definition
growing organisms and identifying the effect if the antibiotic
Term
Broad or narrow spectrum
Definition
wide variety antibiotic versus more organism group specific
Term
Bacterial resistant:
Definition
bacteria is resistant to an antibiotic
Term
Super infections
Definition
adverse effect of anti-infective therapy is the appearance of secondary infections called _________ that occur when microorganisms normally present in the body are killed by the drug.
Term
sulfonamides
Definition
1st group of antibiotics developed
Term
Sulfonamides
Definition
Inhibits folic acid in bacteria's cell metabolism
Slows rate of bacterial multiplication
Term
bacteriostatic
Definition
action of sulfonamides
Term
certain UTI's, bronchitis, upper respiratory infection (URI), ear infection, burns
Definition
sulfonamides are used to treat (5)
Term
sulfonamides
Definition
may cause Steven's Johnson Syndrome
Term
trimethoprim-sulfamethoxazole (Bactrim, Septra)
Definition
combination drug used for UTI, Pneumocystis, and ear infections
Term
anorexia, N/V, diarrhea, abdominal Pain, chills, fever, stomatitis
Definition
adverse reactions to sulfonamides
Term
hemolytic anemia, aplastic anemia & thrombocytopenia
Definition
sulfonamides can cause these blood problems
Term
sulfonamides, tetracycline, fluoroquinlones, aminoglycosides
Definition
which antibiotic groups have photo sensitivity
Term
all antibiotics
Definition
which antibiotics have renal implications so the patient should be on I/O
Term
Penecillins, Cephalosporins
Definition
which antibiotics have 4 subgroups known as "generations"
Term
penecillins and cephalasporins
Definition
which antibiotic groups are bacterial resistance most likely to happen with?
Term
all antibiotics
Definition
which antibiotic groups cause GI problems
Term
Penicillins, Cephalosporins, Lincosamides
Definition
which antibiotics should be taken on an empty stomach because food interferese with absorption of oral route
Term
penicillins, tetracylcines
Definition
2 antibiotic groups that decrease effectiveness of birth control
Term
cephalosporins
Definition
which antibiotic group causes a disulfiram reaction if taken with alcohol
Term
penicillins, cephalosporins
Definition
antibiotics (2) that may sting if given IM into a large muscle
Term
tetracyclines, flouroquinolones, aminoglycosides, macrolides, lincosamides
Definition
which antibiotic groups should not be given along with antacids
Term
tetracylcines
Definition
which antibiotic group may cause discoloration of teeth in infants and children
Term
tetracyclines - macrolides
Definition
antibiotics that are effective for treating Lyme disease
Term
tetracyclines
Definition
which antibiotic group should dairy products be avoided in because Ca binds with it and decreases its effectiveness
Term
aminoglycosides - monobactams
Definition
which antibiotics types should the nurse monitor for ototoxicity and renal complications
Term
aminoglycosides
Definition
which antibiotic group is used prophylactically during bowel prep surgery to decrease bacteria in the colon
Term
penicillins
Definition
inhibits cell wall synthesis, DNA or RNA synthesis; protein synthesis
Term
bactericidal
Definition
action of penicillins
Term
beta lactam
Definition
penicillins work on the _____ ______ ring of the bacteria
Term
penicillins
Definition
antibiotic that is the initial therapy for staphylococcal disease
Term
natural, penicillinase-resistant, aminopenicillins, extended spectrum PCN's
Definition
four generations of penicillins
Term
penicillin G - penicillin V
Definition
two types of natural penicillins
Term
cloxacillin, methicillin, dicoloxacillin, nafcillin, oxacillin
Definition
5 types of penicillinase-resistant penicillins
Term
amoxicillin, ampicillin
Definition
two aminopenicillins
Term
piperacillin, ticarcillin, carbenicillin
Definition
three extended spectrum penicillins
Term
Penicillin G
Definition
PO, IM, IV drug that is effective against staph
Term
anaphylactic shock
Definition
if PCN and beta blockers are taken together, may increase the risk for _________ __________
Term
bleeding risks
Definition
PCN or cephalasprins should not be taken with anticoagulants because because it increases the ________ ___________
Term
cephalosprins
Definition
contraindicated in people with PCN allergy
Term
aminoglycosides
Definition
interact with cephalasporins to increase risk of nephrotoxicity
Term
cephalosporins
Definition
alcohol should not be consumed with 72 hours of taking these drugs because it can cause a disulfiram reactions
Term
cephalosprins
Definition
effective with all strains of bacteria that are affected by PCN and some that are resistant
Term
cephalosporins
Definition
used to treat UTI's, skin infections, hospital acquired pneumonias, and during perioperative period
Term
1st
Definition
keflex is a ___ generation broad spectrum cephalosporin
Term
Cefotaxime (Claforan)
Definition
broad spectrum, 3rd generation cephalosporin
- cell wall inhibitor
Term
negative
Definition
cefotaxime (claforan) is effect against gram _____ bacteria
Term
aplastic anemia
Definition
rare, but possible side efffect of cephalosprins
Term
bacteriostatic
Definition
action of tetracyclins
Term
tetracylines
Definition
have broad spectrum, but are often not the drug of choice
Term
negative and positive
Definition
tetracylclines are effective against gram _______ bacteria
Term
negative and positive
Definition
tetracylclines are effective against gram _______ bacteria
Term
tetracylcine (sumycin)
Definition
drug of choice against H pylori and many other microorganisms
Term
tetracyclines
Definition
may increase risk for digitalis toxicity for pts on digitalis
Term
mycin
Definition
all macrolides in in "____"
Term
macrolides
Definition
act by causing changes in protien function and synthesis of bacteria
Term
erthromycin
Definition
preferred drug for pertussis, Legionnaires disease, m pneumonia, and diptheria
Term
negative and positive
Definition
macrolides are effective against gram ______ bacteria
Term
macrolides
Definition
effective against spirochetal infections (syphilis, lyme disease, gonorrhea, chlamydia, mycoplasma)
Term
bactericidal
Definition
action of aminoglycosides
Term
not
Definition
aminoglycosides can or can not be used during pregnancy
Term
gentamicin
Definition
aminoglycocide of choice for serious urinary, respiratory, nervouc, and GI infections
Term
genotopic
Definition
topical formula of Gentamicin used for external eye
Term
ototoxicity and nephrotixicity
Definition
two major side effects of aminoglycosides
Term
kanamycin and neomysin
Definition
2 aminoglycosides that require monitoring for hepatic coma and swallowing problems
Term
bactericidal
Definition
action of fluoroquinlones
Term
positive and negative
Definition
flouroquinlones are effective againts gram _____ bacteria
Term
negative
Definition
cipro (ciprofloxican) is more effective against gram _____ bacteria
Term
cipro (ciprofloxican)
Definition
most widely used fluoroquinlone
- treats resp infections, bone and joint infections, GI infections, opthalmic infections, sinusitis, and prostatitis
Term
levaquin
Definition
may cause tendon rupture
Term
fluoroquinolones
Definition
drugs that effect changes in cartlidge in children
Term
clindamycin, lincomycin
Definition
two lincosamides
Term
lincosamides
Definition
used against gram + and - when PCN and erythromycin are not effective
Term
carbapenems
Definition
drugs that end in "em" (impenem-cilastatin, meropenem, erapenem)
- have the broadest spectrum of any antibiotics
Term
bactericidal
Definition
action of carbapenems
Term
carbapenems
Definition
used to treat peritonitis, meningitis, bone, joint, soft tissue infections, septicemia endocarditis, encephalitis
Term
aztreonam (Azactam)
Definition
the only monobactam drug
Term
negative
Definition
monobactam drug Aztreonam (Azactam) is only effective against gram _____ bacteria
Term
bactericidal
Definition
action of monobactams (astreonam (Azactam))
Term
6-24 months
Definition
antitubercular medications need to be taken for _________
Term
TB
Definition
several antibiotics may be prescribed for this disease since it is slow growing and develops resistance
Term
INH (isoniazid)
Definition
drug of choice for treating TB
Term
Rifampin
Definition
commonly prescribed TB drug that turns everything orange
Term
antituberculins
Definition
s/e blurred/colored vision, difficulty voiding, fever, GI, hearing, red discolored body fluids, numbness/tingling in extremities, weight gain, edema, dark urine
Term
with
Definition
antituberculins should be taken with or without food
Term
vancomycin
Definition
reserved for severe gram + infections
- used after other antibiotics ineffective
Term
vancomycin
Definition
s/e red man syndrome, flushing, hypotension, rash to upper body, nephrotoxicity, ototoxicity
Term
zyvox
Definition
drug used to treat VRE
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