Term
| Where is NE synthesized? Rate limiting step? What are the four compounds in the synthesis? |
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Definition
adrenergic neuron or adrenal
Tyrosine hydroxylase is rate limiting
L-tyrosine, l-dopa, dopamine, NE |
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Term
| What is the ratio of NE to Atp in the vesicle? |
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Definition
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Term
| How much NE is reuptaken? |
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Definition
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Term
| What two enzymes metabolize NE? |
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Definition
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Term
| Is NE metabolized quickly in the CNS? |
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Definition
| no but anywhere outside cns it is metabolized very quickly |
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Term
Rank them according to alpha activity
E, isoproterenol, and NE |
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Definition
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Term
Rank them according to beta activity
E, isoproterenol, and NE |
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Definition
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Term
| For phenylethanolamine, what happens when you increase the size of R1(group off of the amine)? |
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Definition
decreases alpha activity
increases beta activity |
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