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PDA I Exam 4 Fall 2008
Cholinergic Transmission II
37
Health Care
11/26/2008

Additional Health Care Flashcards

 


 

Cards

Term
Nicotine, lobeline, epibatide, and DMPP are examples of this type of drug.
Definition
Ganglion Stimulant
Term
Lobeline is used for _________.
Definition
Smoking Cessation
Term
Epibatide is used for:
Definition
Pain relief (still experimental)
Term
DMPP is used as:
Definition
An experimental tool
Term
Trimetaphan is used:
Definition
To control hypotension during surgery
Term
Hexamethonium and trimetaphan are examples of:
Definition
Ganglion blocking drugs
Term
This enzyme quickly breaks down acetylcholine in the synapses:
Definition
Acetylcholinesterase (AChE)
Term
Procaine, succinylcholine, and propanidid are hydrolyzed by this enzyme which is similar to ACh in structure, but differs in distribution
Definition
Butyrlcholinesterase (BuChE)
Term
Edrophonium is an example of a:
Definition
Short acting anticholinesterase
Term
Edrophonium is used in the diagnosis of:
Definition
Myasthenia gravis
Term
Neostigmine, pyridostigmine, and physostigmine are examples of:
Definition
Medium duration anticholinesterases
Term
Neostigmine is clinically used to treat:
Definition
Myasthenia gravis
Term
Pyridostigmine is clinically used for:
Definition
Myasthenia gravis
Term
Physostigmine is clinically used to treat:
Definition
Glaucoma
Term
Dyflos, ecothiopate, parathion are examples of this type of drug:
Definition
Irreversible anticholinesterases
Term
Ecothiopate has been used clinically for:
Definition
Glaucoma
Term
Dyflos and parathion have been used as:
Definition
Insecticides
Term
Sarin, tabun, and soman have been used as:
Definition
War gases
Term
Anticholinesterases have this effect on the autonomic synapses:
Definition
Enhances ACh activity
Term
Anticholinsterases have this effect on the neuromuscular junction:
Definition
Reverse the effects of tubocurarine and myasthenia gravis
Term
Anticholinesterases have this effect on the CNS:
Definition
Convulsion, depression, unconsciousness, respiratory failure. Also used to treat dementia.
Term
Hemicholinium, triethylcholine, and vesamichol are used to ______________.
Definition
Inhibit ACh synthesis
Term
This drug blocks reuptake of choline by choline transporter at the presynaptic membrane:
Definition
Hemicholinium
Term
This drug is a precursor to a cholinergic false transmitter:
Definition
Triethylcholine
Term
This drug blocks ACh transport into synaptic vesicles:
Definition
Vesamichol
Term
Aminoglycoside antibiotics, botulinum toxin, and B-bungarotoxin inhibit________.
Definition
ACh release
Term
These drugs block calcium entry into the nerve terminal:
Definition
Aminoglycoside antibiotics
Term
Streptomycin and Neomycin are examples of:
Definition
Aminoglycoside antibiotics
Term
This protease drug cleaves SNAREs involved with exocystosis:
Definition
Botulinum toxin
Term
This drug is a neurotoxic phospholipase A2 that blocks ACh release:
Definition
B-Bungarotoxin
Term
This chronic autoimmune neuromuscular disease is caused by a defect in the transmission of nerve impulses to muscles:
Definition
Myasthenia gravis
Term
This disease is caused by autoantibodies blocking, altering, or destroying the nACh receptors at the neuromuscular junction:
Definition
Myasthenia gravis
Term
Symptoms of myasthenia gravis include:
Definition
Facial muscle weakness, eye drooping, double vision; difficulty in breathing, talking, chewing, or swallowing; muscle weakness in arms and legs; fatigue brought on by repetitive motions
Term
Myasthenia gravis can be treated by:
Definition
Anticholinesterases, steroids, and immunosuppressant drugs
Term
Neostigmine and pyridostigmine are:
Definition
Anticholinesterases used to treat Myasthenia Gravis
Term
Prednisone is:
Definition
A steroid used to treat myasthenia gravis
Term
Azathioprine is:
Definition
An immunosuppressant drug used to treat myasthenia gravis