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PD Exam 2
PD Exam 2
296
Other
Graduate
11/30/2009

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Term
What respiratory rate corresponds to bradypnea and tachypnea?
Definition
Below 10/min = bradypnea.
Above 20/min = tachypnea.
Term
What conditions lead to orthopnea?
Definition
CHF, diaphragmatic paralysis, SVC syndrome and mediastinal mass.
Term
What is the Kussmaul pattern of respiration? Causes?
Definition
Rapid, deep respirations. Causes include metabolic acidosis, DKA, ethanol and ketoacidosis.
Term
What is biot pattern of respiration? Cause?
Definition
periodic apnea intermixed with rapid deep breathing. Caused by brainstem damage.
Term
What is the Cheyne-Stokes pattern of respiration? Cause?
Definition
Periodic, repetitive apnea. Periods of breathing, the depth increases with each breath. Caused by CHF.
Term
What is the Sleep apnea pattern of respiration?
Definition
Intermittent period of apnea to 20 seconds while asleep. Caused by obesity or a retrosternal goiter.
Term
Describe the normal tracheal findings on inspection.
Definition
Trachea is slightly tilted to right. As a result, the clavicular insertion of right Sternomastoid is slightly more prominent and the space between trachea and sternomastoid is smaller compared to left.
Term
Describe the difference between pull and push abnormal lung findings.
Definition
Pull is a loss of lung volume and push is when there are space occupying masses.
Term
Describe the tracheal deviation seen with tension pneumothorax, massive pleural effusion and atelectasis.
Definition
Tension pneumothorax = trachea is pushed away from side of pneumothorax.
Pleural effusion = trachea is pushed away from the side of effusion.
Atelectasis = trachea is pulled toward the side of atelectasis.
Term
Describe the changes seen on percussion with tension pneumothorax, massive pleural effusion and atelectasis.
Definition
Tension pneumothorax = tympany.
Pleural effusion = dullness.
Atelectasis = dullness.
Term
What vertebra can be used to estimate the height of the ileum?
Definition
L4
Term
What is the level of the carina for the anterior and posterior?
Definition
Anterior is the level of the 3rd intercostal space and the posterior is at the level of T4.
Term
Which mainstem bronchus is more horizontal and is shorter?
Definition
The right one.
Term
What causes clubbing?
Definition
It is seen with chronic pulmonary disorders and is caused by peripheral trapping and clumping of large immature platelets that promote angiogenesis and bone growth.
Term
Describe pectus carinatum, pectus excavatum, and kyphoscoliosis.
Definition
Pectus carinatum = thick AP diameter but narrow shoulder and body width (pigeon-chested).
Pectus excavatum = sunken in chest.
Kyphoscoliosis = twisted spine.
Term
What is the normal range of chest expansion in inches?
Definition
2-5 inches
Term
How will non obstructed consolidation, obstructed consolidation, pleural effusion and lobectomy affect tactile fremitus?
Definition
Non-obstructed consolidation will lead to increased TF. Obstructive will lead to decreased TF. Pleural effusion will lead to decreased TF will a thin rim of increased TF over the pleural effusion. Lobectomy will have absent TF.
Term
What percentage of the lung is air?
Definition
99%
Term
What is the normal range for diaphragmatic excursion?
Definition
5-6 cm
Term
What conditions could lead to dullness on lung percussion?
Definition
Dullness: (Mass, Atelectasis, Consolidation, Pleural effusion).
Term
What conditions could lead to hyper-resonance on lung percussion?
Definition
Hyper-resonance: (Emphysema, Asthma, Pneumothorax, Blebs).
Term
What conditions could lead to decreased diaphragmatic excursion?
Definition
Decreased diaphragmatic excursion: (Emphysema, paralysed diaphragm)
Term
What are the two physiologic reasons for lung percussion dullness?
Definition
consolidated lung tissue and effusion
Term
What are the two physiologic reasons for hyper-resonance?
Definition
obstructive lung disease and pneumothorax
Term
How deep can percussion measure?
Definition
5 centimeters
Term
Describe where you hear bronchial and vesicular breath sounds.
Definition
Breath sounds heard over the tracheobronchial tree are called bronchial breathing and breath sounds heard over the lung tissue are called vesicular breathing.
Term
Where are the only spots that bronchial breaths are heard on auscultation?
Definition
trachea, right sternoclavicular joint and posterior right interscapular space..
Term
Describe the differences heard on auscultation between bronchial and vesicular breath sounds.
Definition
Bronchial = sounds over the trachea have a higher pitch, louder, inspiration and expiration are equal and there is a pause between inspiration and expiration.
Vesicular = lower pitched and softer than bronchial breathing. Expiration is shorter and there is no pause between inspiration and expiration.
Term
Are breath sounds louder in the bases or apices in the erect position?
Definition
Louder in the bases in the erect position
Term
Which auscultation findings are usually pathologic?
Definition
wheezes, crackles, rales and pleural friction rubs.
Term
Describe where the lung abnormality is with crackles, rhonchi and stridor.
Definition
Crackles = terminal airway disease (interstitial/alveolar edema).
Rhonchi = proximal airway disease.
Stridor = upper airway obstruction.
Term
What is the typical clinical presentation of a child with epiglottitis? How should you handle this situation?
Definition
The child will sit forward and drool as the tender epiglottis prevents swallowing saliva. If you see this, call anesthesia immediately. Do not attempt to visualize or manipulate the epiglottis, as even small perturbations can cause immediate laryngeal spasm and death.
Term
Symptoms of pneumonia without signs of consolidation and/or a neg CXR suggests?
Definition
atypical pneumonia (Mycoplasma, Chlamydia, Legionella).
Term
Is hilar lymphadenopathy with pneumonia normal for children? Adults?
Definition
Hilar lymph node enlargement is normal in children but NOT in adults
Term
Should you use a CXR to confirm resolution of a pneumonia?
Definition
No, use PE findings.
Term
Describe the PE findings with a pleural effusion. (percussion, auscultation, special test and fremitus)
Definition
a. Dullness to percussion.
b. Absence of breath sounds.
c. No egophony, bronchophony or whisper pectoriloquy.
d. Fremitus is absent (no vibration). fremitus is very useful in distinguishing an effusion from consolidation as the cause of an area of dullness to percussion.
Term
What are some common conditions that cause wheezing?
Definition
Aspiration , Asthma, Certain drugs, COPD, Endobronchial tumors, Endotracheal tumors, Inhaled irritants, Pulmonary edema, Tracheal stenosis, Viral tracheobronchitis, Vocal cord dysfunction
Term
What are the S&S of a pink puffer?
Definition
COPD, pursed lips, thin, tachypnea, with dyspnea
Term
What are the S&S of a blue bloater?
Definition
COPD, cough with sputum x 3 months min, blue due to lack of Oxygen, peripheral edema, dyspnea, prone to right sided heart failure.
Term
Does pink puffer or blue bloater have a better prognosis?
Definition
Pink puffer has a better prognosis.
Term
Describe the sputum seen with bronchiectasis and lung abscesses.
Definition
Can be purulent and offensive and will be streaked with blood.
Term
Describe the sputum seen with pulmonary edema.
Definition
pink, frothy and watery
Term
Describe the sputum seen with pulmonary TB/Neoplasm.
Definition
Can be any type of sputum.
Term
Describe the sputum seen with chronic bronchitis.
Definition
Scant, mucopurulent, mucoid with flecks of yellow/green pus.
Term
Describe the sputum seen with pneumonia (Pneumococcal or strep pneumonia).
Definition
Bloody or rusty colored.
Term
Describe the sputum seen with pseudomonas.
Definition
Moldy, necrotic tissue odor.
Term
Describe the sputum seen with Klebsiella pneumonia.
Definition
Thick ,Current-Jelly, Gelatinous, Brick red, Laced with pus
Term
What immunoglobulin is affected with allergic asthma?
Definition
IgE
Term
What is the cause of exercise induced asthma?
Definition
Release of leukotrienes from bronchial mast cells.
Term
Where does congenital emphysema affect most commonly? What are the physiologic changes that occur with emphysema?
Definition
Congenital emphysema usually affects the upper lobes and the physiologic changes are that there is a loss of alveoli.
Term
Name and describe the neurologic syndrome that commonly occurs with a cancer in the upper lobe of the lungs.
Definition
Horner's syndrome - ptosis, miosis and facial anhidrosis.
Term
Rank the top 3 most common types of lung cancer.
Definition
Squamous cell (40%), Adenocarcinoma (30%) and Small cell (20%).
Term
Describe the most common location for lung squamous cell, adenocarcinoma and small cell.
Definition
Squamous = upper lobes and mainstem bronchus. Adeno = peripheral lung fields. Small = peripheral lung fields and possibly in the central.
Term
Describe the growth rate for lung squamous cell, adenocarcinoma and small cell.
Definition
Squamous and adenocarcinoma grow slow (adeno is the slowest) and small cell grows rapidly.
Term
Describe the metastatic tendencies lung squamous cell, adenocarcinoma and small cell.
Definition
Squamous is late to metastasize, Adenocarcinoma is early to metastasize and small cell has usually metastasized before it is diagnosed.
Term
What are "smoker's fingers"?
Definition
yellow-brown staining of the finger nails
Term
What does spirometry measure? Uses?
Definition
The amount and rate of air a person breathes in order to diagnose illness or determine progress in treatment.
Term
Describe what happens in the lungs with obstructive pulmonary diseases and how they affect residual volume and functional residual capacity.
Definition
Obstructive pulmonary conditions cause the patients to have hyperinflated lungs due to the trapping of air in the lungs. The residual volume and the functional residual capacity are both elevated.
Term
Describe what happens in the lungs with restrictive pulmonary diseases and how they affect TLC, inspiratory capacity and vital capacity.
Definition
The lungs are less compliant and cannot expand normally. TLC, inspiratory capacity and vital capacity are all reduced.
Term
Describe the differences in vital capacity (max amount of air expired after max inspiration) for obstructive vs. restrictive pulmonary disorders.
Definition
Obstructive will have a normal or decreased VC and restrictive will definitely have a decreased VC.
Term
Describe the differences in FEV1 (forced expiratory volume in 1 sec) for obstructive vs. restrictive pulmonary disorders.
Definition
Obstructive will definitely be decreased and restrictive can be normal or decreased.
Term
Describe the differences in residual volume and total lung capacity for obstructive vs. restrictive pulmonary disorders.
Definition
They can be normal or increased for obstructive and they will be decreased for restrictive.
Term
Describe the differences in the RV/TLC ratio for obstructive vs. restrictive pulmonary disorders.
Definition
Obstructive will be increased and restrictive can be normal or increased.
Term
What are some common causes of restrictive pulmonary disorders?
Definition
PAINT - Pleural (effusions or plaques), Alveolar (pulmonary alveolar proteinosis), Interstitial (fibrosis), Neuromuscular (ALS - Amyotrophic lateral sclerosis or Lou Gehrig disease, Myasthenia gravis) and Thoracic (Scoliosis).
Term
What are some common causes of obstructive pumonary disorders?
Definition
Asthma, COPD, Tumors, Foreign bodies and Scarring/Strictures.
Term
Describe the procedure and use of incentive spirometry.
Definition
Patient exhales completely and then inhales smoothly until max inhalation is achieved. used in post-op, in-patients, ICU and as bronchial prophylaxis to maintain airway patency and to prevent/correct atelectasis.
Term
Why are "spacers" efficient when delivering inhalation therapy?
Definition
They slow down aerosol coming from the inhaler and less of the drug hits the back of the mouth and more gets to the lungs. Less medication is needed for an effective dose to reach the lungs which results in fewer side effects.
Term
What are the 5 main functions of the skin?
Definition
Protect the internal structures, prevent the entry of microorganisms, regulate temperature, excretion, and production of vitamin D.
Term
Describe the layers of the epidermis from superficial to deep.
Definition
Corneum, lucidum, granulosum, spinosum and basale.
Term
Describe the layers of the dermis from superficial to deep.
Definition
Papillary and then reticular.
Term
Which layer of skin contains the Pacinian corpuscles (sensory receptors), sweat glands, lymph vessels, and hair follicles?
Definition
Reticular layer of the Dermis.
Term
Which layer of the skin creates "fingerprints"?
Definition
The papillary layer of the dermis.
Term
Which layer of the epidermis is found only in the palms and soles of the feet?
Definition
The stratum lucidum.
Term
Describe the three types of sweat glands (eccrine, apocrine and sebaceous) and what they secrete.
Definition
Eccrine = most common sweat gland that is found throughout the body and secretes sweat to maintain body temperature.
Apocrine = found primarily in the axilla and anal region and become active during puberty and secrete pheromones.
Sebaceous = found surrounding hair follicles and they secrete sebum to keep hair and skin moist.
Term
Describe the differences in the two types of body hair (vellus and terminal).
Definition
Vellus – firm delicate hair covers most of body, inconspicous
Terminal – Coarser, thicker and pigmented. Scalp, eyebrows and genital hair.
Term
Define the nail matrix, eponychium and lunula.
Definition
Matrix is the proximal nail fold. Eponychium is the cuticle. Lunula is the white half moon part of the nail base.
Term
What are the 4 pigments that determine skin color?
Definition
Melanin, carotene, oxyhemoglobin and deoxyhemoglobin.
Term
What are the 9 major groups of dermatological diseases based on morphology?
Definition
Eczema/dermatitis, maculopapular, papulosquamous, vesiculobullous, pustular, urticaria, nodular, telangiectasias and hyper/hypomelanosis.
Term
What is skin with decreased turgor a sign of?
Definition
dehydration
Term
What is skin with decreased mobility a sign of?
Definition
edema
Term
Describe the distribution of lesions that occur in: annular, arcuate, bizarre, confluent, discoid, iris and reticular formations.
Definition
Annular – ring shaped.
Arcuate – partial ring.
Bizarre- irregular.
Confluent- run together.
Disccoid- disc shape with no central clearing.
Iris – circle within a circle.
Reticular – marble like.
Term
What are the ABCDE's of melanoma?
Definition
Asymmetry, Border irregularity, Color variation, Diameter larger than 6mm, Elevation.
Term
:Small flat nonpalpable spot, up to 1 cm, freckles.
Definition
Macule
Term
:larger flat nonpalpable spot, more than 1 cm, vitiligo, café au lait spots
Definition
Patch
Term
:palpable, elevated solid mass up to 1 cm
Definition
Papule
Term
:well circumscribed hyperpigmented papule or macule, known as a birthmark or a mole.
Definition
Nevi
Term
:Palpable, elevated solid mass greater than 2 cm
Definition
Tumor
Term
:Superficial elevations of the skin filled with fluid, smaller than 1 cm
Definition
Vesicle
Term
:Superficial elevations of the skin filled with fluid, greater than 1 cm
Definition
Bulla
Term
:Superficial elevations of the skin filled with pus
Definition
Pustule
Term
:Localized accumulation of purulent material in the dermis
Definition
Abscess
Term
:Plugged opening of sebaceous gland
Definition
Comedome
Term
:Necrotizing form of inflammation of a hair follicle
Definition
Furuncle
Term
:coalescence of several furuncles
Definition
Carbuncle
Term
:Small harmless tumors of the skin caused by human papilloma virus, gray to flesh colored nodules raised from the skin surface, and covered with rough, hornlike projections.
Definition
Verrucae (warts)
Term
:Conical structure of keratin pointing to the dermis, due to pressure on the skin.
Definition
Corn
Term
:thickening of epidermal keratin due to pressure and friction
Definition
Callus
Term
:exfoliated epidermis, (dandruff, psoriasis)
Definition
Scaling
Term
:dried residue of pus, serum or blood
Definition
Crusting
Term
:roughening and thickening of epidermis witht accentuation of the normal skin lines
Definition
Lichenification
Term
:Pink or red discloration of the skin
Definition
Erythema
Term
:Reddish – purple macules 1-3mm
:Reddish – purple macules > 3mm
Definition
Petechiae and Purpura
Term
:Purple or purplish blue macules, fade over time, “Black & Blue” marks
Definition
Ecchymosis
Term
:Fine, irregular blood vessels
Definition
Telangiectasias
Term
:Central red macules with radiating spider like arms
Definition
spider angioma
Term
:Small red macules
Definition
Cherry angioma
Term
:Replacement of destroyed dermis with fibrous tissue
Definition
scar
Term
:Elevated scar that grows beyond wound
Definition
Keloid
Term
:Minute, slightly raised tunnel in epidermis, (Scabies)
Definition
Burrow
Term
:Linear crack from epidermis to dermis
Definition
Fissure
Term
:Superficial linear traumatized area
(Abrasion, scratch)
Definition
Excoriation
Term
:Thinning of the skin, (Striae)
Definition
Atrophy
Term
:Loss of part of epidermis, (Vesicle rupture)
Definition
Erosion
Term
:Loss of epidermis and dermis
Definition
ulcer
Term
:>10mm, purple, palpable (ecchymosis is non-palpable)
Definition
hematoma
Term
Describe stage I-IV pressure ulcers.
Definition
I - reddness or purple shade to skin with increased warmth or coolness.
II - partial thickness skin loss involving epidermis and/or dermis.
III - Full thickness skin loss but it does not extend through the fascia.
IV - Full thickness skin loss and destruction of muscle and/or bone.
Term
What is a patch test used to diagnose?
Definition
It is used to diagnose if someone is allergic to certain stimuli.
Term
What is Darier's sign?
Definition
When you scrape the skin and someone becomes swollen, itchy and red.
Term
What is Auspitz's sign?
Definition
bleeding after psoriasis is scraped off
Term
What is Nikolsky's sign?
Definition
blisters that spread upon pressure to the skin
Term
What is Paring Hyperkeratotic Lesions used to differentiate?
Definition
Differentiation of warts and calluses
Term
What does the Tzank smear detect? What kind of stain is used?
Definition
Looks for Tzanck cells which are indicative of herpes or varicella. use Giemsa or Wright stain.
Term
Describe Moh's procedure.
Definition
Highly specialized method of excision where you debulk obvious tumor, then excision is performed in stages, allows for the smallest surgical margins and defect.
Term
What is cryosurgery typically reserved for?
Definition
Used for small, superficial, nonmalignant lesions (warts)
Term
What are the two stages of tanning due to sun exposure?
Definition
Immediate pigment darkening due to UVA and a photochemical change in melanin and then within 72 hours new malanin is synthesized.
Term
What time of day should you avoid sun exposure?
Definition
11am to 3pm
Term
What are the effects of a cool solution and Tepid solution wet dressing?
Definition
Cool solution = anti-inflammatory effect
Tepid solution = debridement effect
Term
What is the major use of topical corticosteroids?
Definition
inflammatory skin disorders
Term
What are some risks of topical steroid use?
Definition
Atrophy, telangiectasia, purpura, perioral dermatitis, rosacea, masking of initial lesion, rebound tachyphylaxis, pigmentation abnormalities and systemic absorption.
Term
Describe the alopecia associated with androgen-mediated.
Definition
frontal, temporal and occipital hair loss.
Term
Describe the hair loss seen with arterial insufficiency and venous stasis.
Definition
Loss of hair in the extremities
Term
Describe the alopecia seen with alopecia areata.
Definition
patches of hair loss but it regrows
Term
What is Queen Anne's sign of alopecia?
Definition
lateral eyebrow alopecia
Term
What is Trichotillomania pattern of alopecia?
Definition
Habitual pulling out of hair.
Term
What is female pattern alopecia?
Definition
Diffuse and incomplete alopecia
Term
:increased hair growth in androgen sensitive areas.
Definition
Hirsutism
Term
:Spooning, Nail plate thins and becomes inverted, Associated with iron deficiency anemia
Definition
Koilonychia
Term
What is nail pitting associated with?
Definition
Psoriasis
Term
What are white or (Terry's) nails a sign of?
Definition
heart failure or liver disease
Term
What are blue-green nails a sign of?
Definition
Pseudomonas infection
Term
What are brown-yellow nails a sign of?
Definition
Ingestion of phenindione (anticoagulant, vitamin K antagonist)
Term
What are brown-black colored nails a sign of?
Definition
Onychomycosis/Paronychia
Fungal infection
Term
What are nail splinter hemorrhages a sign of?
Definition
usually trauma but can be endocarditis
Term
Describe Beau's lines and Mee's/Muercke's lines of the nails. Associated with?
Definition
Beau's = transverse depressions associated with a severe illness. Mee's/Muercke's = transverse lines associated with an acute or severe illness.
Term
What angle between the nail base and the finger is indicative of clubbing? What causes clubbing?
Definition
Angle over 180 degrees, causes by chronic hypoxia.
Term
Describe the difference between eponychium, onychia and paronychia.
Definition
Eponychium is pus in the proximal fold. Onychia is swelling beneath the entire nail plate. Paronychia is pus in the lateral or medial fold.
Term
Any “splinter hemorrhage” that starts in the germinal matrix and grows outward without any normal bed between the proximal end and the germinal matrix think...?
Definition
Malignant melanoma
Term
White nail plates, think...?
Definition
severe liver disease or heart failure
Term
How do hypothyroidism, thyrotoxicosis and scleroderma each affect skin texture?
Definition
Soft: (Thyrotoxicosis).
Tight: (Scleroderma).
Rough: (Hypothyroidism).
Term
:Typical erythematous plaques topped by a silver scale. Seen MAINLY in the knees, elbows, scalp, forearms, lumbosacral regions, hands, and feet.
Definition
Psoriasis
Term
What is Keobner Phenomenon?
Definition
Lesions induced in areas of local trauma, such as scratches or surgical scars
Term
:Small drop-like plaques with scales developed after a child having streptococcal pharyngitis
Definition
Guttate Psoriasis
Term
Where is the rash with childhood atopic dermatitis most commonly seen?
Definition
Mainly on the flexural surfaces.
Term
:Marked thickening of the skin seen in areas of atopic dermatitis.
Definition
Lichenification
Term
:Newest topical antibiotic. Requires less application therefore increases compliance.

*2x/day x 5 days vs. the recommended 3x/day x 7 days like with mupirocin, bacitracin or neosporin .
Definition
Altabax
Term
:Chronic cracking, oozing, and scaling that develop on the hands and soles of the feet
Definition
Dyshidrotic Eczema
Term
:“coin-shaped” eczema-round to oval shaped lesions typically over the extensor thighs or abdomen
Definition
Nummular eczema
Term
:skin disorder affecting the scalp, face, and trunk causing scaly, flaky, itchy, red skin.
Definition
Seborrhea
Term
:a large, pink, red, brown patch (which may be scaly in texture) on the chest or back. This first patch is called the herald patch or the mother patch. One to 2 weeks after the appearance of the mother patch, more pink patches will appear along the skin folds of the trunk. After a period of 2 to 10 weeks, the rash disappears on its own (spontaneously).
Definition
Pityriasis Rosea
Term
:a very common genetic follicular condition that is manifested by the appearance of rough bumps on the skin
Definition
Keratosis Pilaris
Term
:a common skin condition mostly occurring in children and usually seen as dry, fine-scaled, pale patches on the face. It is self-limiting and usually only requires use of moisturiser creams.
Definition
Pityriasis Alba
Term
:Most common type of allergic contact dermatitis in the United States
Presents as linear streaks of erythematous papules and vesicles caused by direct contact with the sap of poison ivy, poison oak or poison sumac from leaves, stems, or roots
Definition
Rhus Dermatitis
Term
How is the diagnosis of Tinea Pedis made?
Definition
By the presence of hyphea on KOH prep.
Term
What condition is seen with the "slapped cheek" rash?
Definition
Erythema Infectiosum
Term
Cause of Erythema Infectiosum?
Definition
Parvovirus B19
Term
Cause of Roseola? Describe it.
Definition
Human Herpes Virus type 6. It is an exanthem of rose-pink macules.
Term
:Infected person has a fever lasting 2-4 days followed by a cough, runny nose and red watery eyes. A rash then appears on the face and head which spreads to the torso, hands and feet.
Definition
Measles
Term
When can measles be transmitted?
Definition
4 days prior to and 4 days after the appearance of the rash.
Term
When is Varicella contagious?
Definition
48 hours prior to rash until the lesions have crusted over.
Term
:Flat top violaceous papules of varying sizes and shapes overlying the anterior shin are typical. A network of gray lines, called Wickham’s striae are seen on surface of the lesions.
Definition
Lichen Planus
Term
:Multiple pruritic papules, some excoriated and a few with central black dots, Seen on the wrist and dorsum of the hand with pathognomonic burrows
Definition
Scabies
Term
Disease with the characteristic "Bull's Eye" rash.
Definition
Lyme disease
Term
:signs and symptoms of the disease include sudden onset of fever, headache, and muscle pain, followed by development of maculopapular/petechial rash. The disease can be difficult to diagnose in the early stages, and without prompt and appropriate treatment it can be fatal.
Definition
Rocky Mountain Spotted Fever
Term
Volcano lesion due to a hole in the flesh due to gangrenous tissue is seen with what condition?
Definition
Brown recluse bite
Term
:rough, sandpaper-like plaques occurring on sun-exposed surfaces
Definition
Actinic Keratosis
Term
:Translucent, pearly nodule, depressed center and raised borders, may ulcerate, seen with fair skin, on the face and over 40.
Definition
BCC
Term
:Red scaling, crusting nodule or plaque that can ulcerate and bleed, grows more quickly, and can metatasize to lymph nodes and other organs, May develop from actinic keratosis, seen in fair skinned individuals over 60 on the face or other sun exposed areas.
Definition
SCC
Term
:Irregularly colored plaque with sharp notches and variation of pigment, If untreated, can have fatal metastases, associated with a family history, fair skin and prolonged sun exposure.
Definition
Malignant Melanoma
Term
What are the 4 types of melanoma and which is the most common?
Definition
Superficial spreading, Nodular, Lentigo maligna and Acral lentiginous. Superficial spreading is the most common (70%).
Term
:Dark blue purple macules, papules, nodules and plaques, Start light colored and coalesce into darker lesions, Widely disseminated on legs, trunk, arms, neck and head, Most frequent neoplasm occuring in AIDS patients
Definition
Kaposi's Sarcoma
Term
Which degree burn corresponds to: redness, tenderness, pain, no blistering, and healing within a few days w/ no scar.
Definition
1st degree
Term
What degree burn corresponds to: epidermis and superficial dermis involvement, pink/moist/soft skin, thin blisters, tender skin, heals in 2-3 weeks without scarring
Definition
Superficial partial-thickness 2nd degree burn
Term
What burn degree corresponds to: epidermis and lower dermis involvement, red/blanched white skin with thick blisters, healsin 3-6 weeks with possible scarring.
Definition
Deep partial-thickness 2nd degree burn
Term
What degree of burn corresponds to: full thickness burn that destroys the epidermis and dermis, white/leathery skin with underlyign clotted vessels, skin grafting is needed.
Definition
3rd degree burn
Term
What burn degree is characterized by: full thickness burn extending into the muscle of bone, requires hospital admission.
Definition
4th degree
Term
:Hyperpigmentation and leathery thickening of the skin are seen on the neck and in the axilla or other skin folds
Definition
Acanthosis Nigricans
Term
What is the first line treatment for Acne vulgaris?
Definition
Differin cream or gel 0.1%(Retinoid)
Term
:hyperpigmentation, commonly of the face of women taking oral contraceptives, anticonvulsants or that are pregnant.
Definition
Melasma
Term
A 62 year old school principal with a hx of COPD presents to the ER for evaluation of shortness of breath. You note that his lips, oral mucosa, and tongue are blue. You diagnose a COPD exacerbation. The discoloration of the lips, oral mucosa, and tongue is referred to as:
Definition
Central cyanosis
Term
A 30 year old janitor presents to your clinic for evaluation of increased weight. He drinks a fifth of vodka daily. He has used intravenous drugs in the past but is now “clean.” His sclerae and skin have a yellowish tinge. He has a large abdominal girth. You diagnose him with liver dysfunction. What is the discoloration of his skin called?
Definition
Jaundice
Term
A 72 yo retired secretary is brought to the clinic by her daughter. The daughter is concerned because her mother seems to be more confused; she has gained more weight, but her appetite has decreased, and she seems to be more “swollen” in general. You obtain blood tests and diagnose her with profound hypothyroidism. On examination of the skin, you expect it to feel.
Definition
Cool
Term
A 42 yo receptionist presents to your office for evaluation of multiple moles (nevi). She used to sunbathe a lot when she was younger and went to tanning salons regularly until 2 years ago. You are educating her about melanoma. When evaluating a mole, all of the following characteristics are important to note EXCEPT:
Asymmetry
Irregular borders
Color variation
Diameter smaller than 6 mm
Elevation
Definition
Diameter less than 6mm
Term
A 52 yo office worker presents to your office for evaluation of a bump on his face. It appeared 1 month ago and is growing. He denies fever, chills, or itching. Physical examination reveals a 0.4-cm nodule with a depressed center and a firm, elevated border that is flesh-colored. Based on this information, what is your most likely diagnosis?
Definition
BCC
Term
:Smallest living free organisms, Grow in cell-free media and produce disease without intracellular penetration, Have a cell membrane but no cell wall
Definition
Mycoplasmas
Term
4 major species of Mycoplasmas?
Definition
M. pneumoniae
M. hominis
M. urealyticum
M. fermentans
Term
Treatment of Mycoplasma?
Definition
Erythromycin and Tetracycline
Term
:small bacterial organisms that are obligate intracellular parasites and usually require a vector, responsible for Q fever.
Definition
Rickettsiae
Term
What 4 organisms make up the spirochetes?
Definition
Treponema, Leptospira, Borrelia and Spirillium.
Term
What disease is caused by Treponema? Borrelia?
Definition
Treponema = syphillis, YAWS
Borrelia = Lyme disease
Term
How are anaerobic bacteria often identified in the lab?
Definition
foul odor and presence of gas
Term
What is found in the cell wall of Gram negative bacteria? What 3 major species of bacteria are gram negative?
Definition
LPS in the cell wall. Haemophilus, Pseudomonas and Enterobacteria are gram negative.
Term
What are some examples of enterobacteria?
Definition
E.coli, Klebsiella, Enterobacter, Serratia, Salmonella, Shigella and Proteus.
Term
How do gram positive bacteria and gram negative look on gram stain?
Definition
Gram positive are deep purple, gram negative are pink
Term
What are the 2 gram negative cocci?
Definition
Neisseria and Moraxella
Term
What are some common gram positive bacteria?
Definition
Staphylococcus, Streptococcus, Clostridium, Bacillus, Listeria, Corynebacteria
Term
What main 2 bacteria are IV drug users susceptible to?
Definition
Bacillus and Pseudomonas
Term
What test should you use to diagnose mycobacteria?
Definition
Acid fast stain
Term
What should you use to diagnose fungal infections?
Definition
KOH prep.
Term
:Unusual proliferation of lymphocytes into the bloodstream due to Epstein-Barr virus, symptoms include pharyngitis, lymphadenitis, abdominal pain, fever and malaise.
Definition
Mononucleosis
Term
:sore throat, malaise, fever, whitish exudates that appear on the tonsils and later become a grayish membrane.
Definition
Diphtheria
Term
:runny nose, fever, sneezing, cough with "whoop" in children, low grade fever, cyanosis and apnea.
Definition
Bordetella pertussis (Whooping cough)
Term
Mainly affects the lungs but may also infect the kidney, spine, and brain.
S&S = cough, CP, blood in sputum, weakness, decreased appetite, fever/chills and night sweats.
Definition
Tuberculosis
Term
What are the 2 ways to test for TB?
Definition
Mantoux TB skin test and the special blood test to measure the immune response.
Term
Can someone with latent TB still spread it? Will they have a positive skin test? Do they still need treatment?
Definition
cannot spread, positive skin test, still needs treatment to prevent going to TB.
Term
What corresponds to a positive PPD test for immunocompromised, recent immigrant/drug users/high risk populations, and persons with no known risk factors.
Definition
5mm or more for immunocompromised. 10mm or more for recent immigrant/drug users/high risk populations. 15mm or more for persons with no known risk factors.
Term
What could cause a false positive PPD result?
Definition
infection due to non-TB mycobacteria, BCG vaccine, user error.
Term
What could cause a false negative PPD result?
Definition
very recent TB infection, very old TB infection, user error
Term
What is the principle treatment for TB? Others?
Definition
INH - Isoniazid is principle. Others = rifampin, ethambutol and pyrazinamide.
Term
:Serious disease that causes tightening of the muscles, death in 10%.
Definition
Tetanus "lock jaw" - Clostridium tetani
Term
Which tetanus vaccine is indicated for children younger than 7 and 10-64 if they have never received this vaccine?
Definition
DTaP
Term
Which tetanus vaccine is indicated for patients 65 and over?
Definition
Td
Term
:Strain of Staph aureus that has become resistant to beta-lactams and manifests as necrotizing fascitis and abscesses or endocarditis.
Definition
MRSA or ORSA
Term
MRSA/ORSA treatment?
Definition
sulfa drugs, clindamycin, tetracycline, vancomycin, maggots.
Term
:Inflammation of the lymphatic channels, Caused by Streptococcus pyogenes or Staph, Erythematous streaking arising from a wound or insect bite, Associated lymph nodes are swollen and tender
Definition
Lymphangitis "blood poisoning"
Term
What are the 5 P's of STD history taking questions?
Definition
partners, pregnancy prevention, protection from STDs, practices and past Hx of STDs.
Term
Most common STD in the US?
Definition
Chlamydia
Term
:STD characterized by ocular trachoma, lymphogranuloma venerum, epididymitis, cervicitis, conjunctivitis in newborns, and Reiter’s Syndrome aka (Reactive Arthritis) - Urethritis, conjunctivitis, and arthritis
Definition
Chlamydia
Term
Screening tests for syphilis?
Definition
RPR or VDRL with confirmatory FTA-ABS or TPPA.
Term
Screening test for trichomoniasis?
Definition
Microscopic exam on the vaginal fluid, culture and antigen detection test.
Term
What is the screening test for genital herpes?
Definition
Type-specific serology
Term
What is Gonorrhea commonly co-infected with?
Definition
Chlamydia in 30-40% of cases
Term
Diagnosis of Gonorrhea?
Definition
gram stain, culture and sensitivity, modified Thayer-Martin medium and chocolate agar.
Term
Should pregnant women ever be treated with Quinolones or Tetracycline? Which antibiotic is safe to use in pregnant women?
Definition
No, use Azithromycin
Term
Which STD is termed "The Great Imitator"?
Definition
Syphilis
Term
Describe the primary, secondary and tertiary symptoms of Syphilis.
Definition
Primary = single painless chancre that heals on its own.
Secondary = widespread skin rash.
Tertiary = Internal organ damage, neurological defects, gummas.
Term
:chancre sore that is painful.
Definition
Chancroid
Term
Causative agent for Chancroid?
Definition
Haemophilus ducreyi
Term
:Enlarged lymph nodes or ulcers in the inguinal/genital area, Rectal ulcers/bleeding
Definition
Lymphogranuloma Venereum (LGV)
Term
Cause of Lymphogranuloma Venereum (LGV)?
Definition
3 strains of Chlamydia trachomatis
Term
:1 or more blisters that develop into sores, crust over and heal without scarring.
Definition
Genital Herpes
Term
Can genital herpes be transmitted when sores are not present?
Definition
Yes
Term
:Frothy yellow-green vaginal discharge, Vaginal itching
Definition
Trichomoniasis
Term
Which HIV strain is the more virulent and more infective strain? Less virulent and infective?
Definition
HIV-1 (Global) is more. HIV-2 (W.Africa) is less.
Term
How is HIV diagnosed?
Definition
ELISA with confirmatory Western blot.
Term
What is the diagnostic criteria for AIDS?
Definition
CD4 count below 200 cells/microL
Term
What are some characteristic presenting symptoms of vitamin B12 deficiency?
Definition
peripheral neuropathy (pins and needles sensation in hands and feet).
Term
What kind of anemia has a characteristic burning of the tongue?
Definition
Vitamin B12 and Folate deficiency anemia
Term
Which anemia is commonly seen to have cravings for ice, starch or clay?
Definition
Iron deficiency anemia
Term
Which anemia is seen with "chipmunk facies"?
Definition
Thalassemia major
Term
What anemia is seen with "frontal bossing" and "hand-foot" syndrome?
Definition
Sickle cell
Term
Which anemia is seen most commonly with a patient with a smooth, beefy red tongue?
Definition
Vitamin B12 deficiency
Term
If a guiac test on stool reveals occult blood, what anemia is indicated?
Definition
Iron deficiency
Term
Which anemia is most likely to have neurologic problems?
Definition
Vitamin B12
Term
Which leukemia is the most common in childhood?
Definition
ALL
Term
What is the most common leukemia in elderly men?
Definition
CLL
Term
What kind of cells will be present on peripheral smear with CLL?
Definition
smudge cells
Term
What is indicative of AML on peripheral smear?
Definition
Auer rods
Term
Which leukemia is seen with a Philadelphia chromosome?
Definition
CML
Term
How is CML differentiated from a leukemoid reaction?
Definition
CML has a low LAP score.
Term
Common signs and symptoms of a lymphoma?
Definition
Night sweats, pruritis, stridor, GI bleeding, back pain, hepatosplenomegaly, abdominal/head/neck/chest mass.
Term
What condition is characterized by Reed Sternberg cells in lymph node tissue that is seen on a smear?
Definition
Hodgkin's lymphoma
Term
Where is Haemophilis likely to infect?
Definition
respiratory tract
Term
Mono Tx?
Definition
steroids to prevent airway compromise
Term
Diptheria Tx?
Definition
Equine diptheria anti-toxin
Term
Tetanus Tx?
Definition
antibiotics, metronidazole, tetanus immune globulin, muscle relaxers (Diazepam).
Term
RMSF Tx?
Definition
Doxycycline
Term
Lyme Disease Tx?
Definition
Doxycycline
Term
What STDs are screened in all patients first visits? Women?
Definition
All are screened for Syphilis and Hep A/B. Women are also screened for Chlamydia, Trichomoniasis (if fluid) and Gonorrhea.
Term
What is the leading cause of preventable infertility and ectopic pregnancy in the US?
Definition
Chlamydia
Term
Chlamydia Tx?
Definition
Doxycycline
Term
Gonorrhea Tx?
Definition
Ceftriaxone, Cefixime, Ciprofloxacin and Doxycycline (for Chlamydia).
Term
What are some complications of Gonorrhea in women?
Definition
Gland infection, PID and Fitz-Hugh-Curtis syndrome.
Term
Syphilis Tx?
Definition
Penicillin G IV
Term
Chancroid Tx?
Definition
Ceftriaxone, Azithromycin, Erythromycin
Term
LGV Tx?
Definition
Doxycycline (same as Chlamydia)
Term
Trichomoniasis Tx?
Definition
-azoles
Term
Most common cause of vitamin B12 deficiency?
Definition
pernicious anemia
Term
What ethnic groups is G6PD seen with commonly?
Definition
AA, Mediterranean, and Middle East
Term
What ethnic groups is Thalassemia seen with commonly?
Definition
Mediterranean and SE Asian
Term
What ethnic group is commonly seen with Hereditary Spherocytosis?
Definition
N. European
Term
What anemia is most common with vegetarians?
Definition
B12 deficiency
Term
What anemias are seen with alcoholism?
Definition
Folate deficiency, iron deficiency, and sideroblastic (inability to incorporate iron to make heme)
Term
Most common occupational anemias?
Definition
Aplastic (benzene or ionizing radiation) and Lead poisoning
Term
What kind of anemia results from chronic GI bleed?
Definition
Iron deficiency
Term
What kind of anemia has nail changes (brittle, flattening and spooning)?
Definition
Chronic iron deficiency
Term
What anemias are seen with cheilosis?
Definition
Iron deficiency and megaloblastic anemias
Term
Where would the soft systolic ejection murmur heard with severe anemia be heard best?
Definition
Pulmonic area
Term
Which anemias are macrocytic?
Definition
hemorrhagic, folate deficiency, B12 deficiency, hypothyroidism, alcoholism, liver disease.
Term
Which anemias are microcytic?
Definition
Iron deficiency, Thalassemia, Lead poisoning
Term
Which anemias are normocytic?
Definition
Aplastic, Anemia of chronic disease, Hemolysis, Renal failure, G6PD
Term
What are the only noticeable differences between Hemophilia A and B that I could find on the slides?
Definition
A is more common and has prolonged PT and PTT, B just has a prolonged PTT.
Term
CBC results for ALL?
Definition
pancytopenia with increased number of blasts
Term
CBC results for CLL? Differential seen on smear?
Definition
Anemia, thrombocytopenia, and lymphocytosis. Smudge cells on smear.
Term
CBC results for AML? Differential seen on smear?
Definition
Anemia and thrombocytopenia. Auer rods seen on smear.
Term
CBC results for CML? Differential seen on smear?
Definition
Anemia, thrombocytosis and leukocytosis. Philadelphia chromosome (I know its not on a smear but I didnt want the question to give it away).
Term
Malignancy of what cells leads to Non-Hodgkin's lymphoma?
Definition
B cells
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