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Term
Muscarinic receptors:
M1 act on what in the body?
M2 ?
M3 ? |
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Definition
M1 CNS; Stomach (gastric parietal cells)
M2: CNS ; Heart; Smooth Muscle mss.
M3: Exocrine glands; bladder; Smooth Muscle mss.; blood vessels (endothelium) |
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Term
| the antidote to Atropine (which crosses the BBB) overdose is? |
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Definition
| Phyostogmine or pilocarpine |
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Term
In organophosphate poisoning symptoms include (Sludge)
(Salivation, Lacrimation, Urination, Diaphoresis, Gastrointestinal motility, Emesis)
What drug can you treat this with? |
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Definition
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Term
| Atripine Toxcity = what effects |
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Definition
Xerostomia; Mydriasis; Blurred vision; Tachycardia; Hot Flushed skin; Agitation; Delirium; Hallucination; Excitation; Rapid respiration followed by depression (respiratory failure death) |
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Term
Name the types of drugs that are
parasympathomimetic |
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Definition
Muscarinic Agonists
(a) Achetylcholine & Choline esters (Bethancol & Carbachol)
(b) Cholinomimetic alkaloids (Pilocarpine)
1.2. Anticholinesterases
Short - Edrophonium (tensilon)
Med - Phyostigmine, Neostigmine,Pyridostigmine
Long - Dyflos, parathion, Ecothiopate
1.3. Nicotinic Agonists -Nicotine, Lobeline, Anticholinesterases |
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