Shared Flashcard Set

Details

PCFR Drugs 2015
Generic name, Class, Action, Indications, Contraindications, Adverse Reactions, Precautions
167
Medical
Professional
03/13/2015

Additional Medical Flashcards

 


 

Cards

Term
Medications carried per Protocol
Definition
Cardizem, Dilaudid, Haldol, Ketamine, Labetalol, Nitro-bid, Pepcid, Pitressin, Sodium Bicarbonate, Valium, Xoponex, Zofran, Mag Sulfate, Midazolam, Succynocholine
Term
FDA Category X
Definition
Studies in humans/animals show adverse effects which outweigh the benefits of the drug. High fetal risk,
Term
Cardizem (trade name)
Definition
Diltiazem
Term
Cardizem (Class)
Definition
Calcium Channel Blocker
Term
Cardizem (Actions)
Definition
Inhibits the influx of calcium ions during membrane depolarization of cardiac and vascular smooth muscle. Relaxes smooth muscle and slows conductions thru the AV node.
Term
Cardizem (Indications)
Definition
1) PSVT: conversion to sinus rhythm 2) Afib/flutter: temporary control of rapid ventricular rate. 3) HTN 4) Angina Pectoris
Term
Cardizem (Contraindications)
Definition
1) Allergy 2) AMI and Hypotension 3) In Sick Sinus Syndrome
4) 2nd or 3rd d. Heart Block (except in presence of functioning pacemaker) 5) Don't use in Afib/Flutter assoc. with WPW or LGL syndrome
5) V-tach
Term
Cardizem (Adverse Reactions)
Definition
Hypotension, Aflutter, 1st/2nd d. Heart Block, Bradycardia, Chest pain, CHF, Syncope, Ventricular arrhythmias, V-fib, V-tach, N&V, Dizziness, Dyspnea, Headache
Term
Cardizem (Precaution)
Definition
Impaired hepatic or renal function
Term
Cardizem (Dose)
Definition
10mg slow IVP over 2 minutes (May repeat after 10 min. prn) max 20mg.
Term
Cardizem (Onset)
Definition
2-7 minutes
Term
Cardizem (Duration)
Definition
1-3 hours
Term
Haldol (generic)
Definition
Haloperidol
Term
Haldol (Class)
Definition
Anti-psychotic; Antipsychotic/Neuroleptic
Term
Haldol (Actions)
Definition
Acts on CNS to depress subcortical areas, midbrain, and ascending Reticular Activating System
Term
Haldol (Indications)
Definition
Acute psychotic disorders; severe behavioral problems in children; may be used in stimulant overdoses.
Term
Haldol (Adverse Reactions)
Definition
Mental depression, Respiratory depression, Cardiovascular depression, Hypotension, EKG changes with IV use (Torsades de Pointe), restlessness, Insomnia, Drowsiness, Seizures, Tachycardia
Term
Haldol (Precautions)
Definition
Be prepared to ventilate; Extreme caution with Parkinson’s patients, Anticoagulatory therapy
Term
Haldol (Dosage)
Definition
5mg IV or IM; Pediatrics (contact medical control)
Term
Haldol (Onset)
Definition
Sedation may occur in minutes. Antipsychotic may take hours, days or weeks,
Term
Haldol (Duration)
Definition
12-24 hours, but may persist for days
Term
Haldol (Pregnancy)
Definition
Category C
Term
Haldol (Notes)
Definition
Use caution in elderly patients
Term
Haldol (Contraindications)
Definition
Hypersensitivity; Agitation secondary to hypoxia or shock; Not to be used in sedative overdoses.
Term
Ketamine (generic)
Definition
Ketalar
Term
Ketamine (Class)
Definition
Non barbiturate anesthetic
Term
Ketamine (Actions)
Definition
Dissociative anesthetic with analgesic and hallucinogenic properties,
Term
Ketamine (Indications)
Definition
General anesthesia in conjunction with other DAI medications; Sub anesthetic for conscious IO placement
Term
Ketamine (Contraindications)
Definition
Hypersensitivity; Sever untreated hypertension, Penetrating eye injury
Term
Ketamine (Adverse Reactions)
Definition
Nausea/vomiting; increased ICP, increased heart rate; increased blood pressure; hallucinations; abnormal behavior
Term
Ketamine (Precautions)
Definition
Make sure DAI medications are prepared prior to induction
Term
Ketamine (Dosages)
Definition
DAI Adult: 2mg/kg IBW; IV/IO max 200mg; Respiratory failure Pedi: 2mg/kg IBW, IV/IO max 54mg; Behavioral emergencies 40mg IM prn
Term
Ketamine (IO sub anesthetic)
Definition
Adult 0.5-1mg/kg, 100 mg max via SLOW; Pediatric 0.25 mg/kg IBW, 25mg max via SLOW
Term
Ketamine (Onset)
Definition
30 seconds IV; 3-4 minutes IM
Term
Ketamine (Duration)
Definition
10-20 minutes IV; 30-45 minutes IM
Term
Ketamine (Pregnancy)
Definition
Category B
Term
Ketamine (Notes)
Definition
Catecholamine release has temporary effect on heart rate and blood pressure.
Term
Labetalol (generic)
Definition
Normadyne; Trandate
Term
Labetalol (class)
Definition
Antihypertensive; non-selective beta blocker
Term
Labetalol (actions)
Definition
dissociative anesthetic with analgesic and hallucinogenic properties; selectively blocks alpha-receptors and non selectively blocks beta-receptors; the alpha blocking actions lead to general vasodilation and reduced peripheral vascular resistance; the net cardiovascular effects are a decrease in blood pressure without reflex tachycardia or significant reduction in heart rate
Term
Labetalol (Indications)
Definition
Hypersensitive emergency
Term
Labetalol (Contraindications)
Definition
ASTHMA (only in the event of acute asthma attack); COPD (Only if you are treating COPD); Bradycardia, Hypotension, CHF or Cariogenic shock; and heart block >1st degree.
Term
Labetalol (Adverse Reactions)
Definition
1) dizziness 2) headache 3) fatigue 4) postural hypotension 5) angina 6) bradycardia 7) CHF 8) nausea and vomiting 9) wheezing 10) dyspnea 11) increased airway resistance 12) bronchospasm
Term
Labetalol (Precautions)
Definition
1) be prepared to ventilate 2) use with caution in patients taking antihypertensive agents 3) monitor vital signs 4) EKG 5) lung sounds 6) be alert for signs of CHF 7) heart block 8) bradycardia 9) postural hypotension 10) bronchospasm
Term
Labetalol (Dosage)
Definition
CVA, Hypertensive Emergencies, Pre-natal emergencies- 10mg slow IVP over 5 minutes, repeat q 10 minutes until desired BP is reached
Term
Labetalol (onset)
Definition
Usually within 5 minutes
Term
Labetalol (Duration)
Definition
3-6 hours
Term
Labetalol (Pregnancy)
Definition
Category C
Term
Labetalol (Notes)
Definition
Labetalol is passed in human breast milk; use in nursing mothers should be done cautiously
Term
Mag Sulfate (aka)
Definition
MgSO4
Term
Mag Sulfate (class)
Definition
Antidysrhythmic, Electrolyte, Anticonvulsant
Term
Mag Sulfate (indications)
Definition
1) Torsades de pointes 2) Seizure secondary to eclampsia 3) severe asthma 4) pre term labor
Term
Mag Sulfate (contraindications)
Definition
1) Hypersensitivity 2) sinus bradycardia 3) pediatrics 4) severe HTN 5) 3rd degree HB 6)Dialysis
Term
Mag Sulfate (Adverse Reactions)
Definition
1) hypotension 2) hypertension 3) dysrhythmias 4) facial flushing 5) diaphoresis 6) depressed reflexes 7) bradycardia
Term
Mag Sulfate (precautions)
Definition
1) may cause circulatory collapse or cardiac and respiratory depression 2) use with caution in renal deficiency
Term
Mag Sulfate (dosage)
Definition
1) Induced hypothermia- 1gm IVP
2) Torsades - Mix 1gm in 10ml NS IVP. Admin over 5min. May repeat X1 for total of 2gm
3) Acute Severe Asthma- mix 1 gm in 10ml NS IVP over 5min.
4) Pre-eclampsia- IV drip 5gms in 250ml D5W infused over 30 minutes 500ml/hr
5) Eclampsia - 4gm IVP over 2 minutes
Term
Mag Sulfate (onset)
Definition
Immediate
Term
Mag Sulfate (Duration)
Definition
30 minutes IV
3-4 hrs IM
Term
Mag Sulfate (Pregnancy)
Definition
Category A
Term
Mag Sulfate (Notes)
Definition
During childbirth emergencies- Magnesium may cause hypotension and decreased respiratory drive. Use with caution.
Term
Midazolam (AKA)
Definition
Versed
Term
Midazolam (class)
Definition
Short acting benzodiazepine
CNS depressant
Term
Midazolam (Actions)
Definition
Pre-synchronized cardioversion
External Cardiac Pacing
Seizures refractory to valium
Sedation for drug assisted intubation
Term
Midazolam (Contraindications)
Definition
Hypersensitivity
Hypotension (MAP <70mmHG)
Term
Midazolam (adverse reactions)
Definition
1) Hypotension 2) respiratory depression 3) headache 4) nausea 5) brady/tachy 6) PVC's 7) AMS 8) Laryngo/Bronchial spasms 9) dyspnea 10) drowsiness
Term
Midazolam (indications)
Definition
Pre-synchronized cardioversion
External cardiac pacing
Seizures refractory to Valium
Sedation for drug assisted intubation
Term
Midazolam (adult dosages)
Definition
1)TCP- 2.5mg IV/IN q 3 min. to effect max 10mg
2)Induced Hypothermia- 2.5 mg IVP, max 10mg
3)Cardioversion- 2.5mg IV/IN r. every 3-5 min. until adequate relaxation max 10mg
4) DAI - Pre intubation 5mg IV/IO; Post intubation - 2.5-10mg IVP
5) Behavioral 5mg IN, IM or IV
Term
Midazolam (adult dosages con't)
Definition
1)Seizures (active w/o IV access) 5mg IM/IN max 10mg; (active seizing w/ IV access) 2.5mg-5mg slow IV titrate to effect.
2) head injuries (if patient combative) 2.5-5mg IVP q 3 minutes max 10mg
3) Eclampsia 2.5mg q 2 minutes IVP w/ a max of 10mg, if refractory to Mag
Term
Midazolam (pedi dosages)
Definition
1) Synch Cardioversion 1.0mg/kg IV/IN q 3-5 min. until adequate relaxation max 5mg
2) Seizures (active seizing w/o IV access) 2.5mg IM/IN max 5mg; (active seizing w. IV access) 2.5mg IVP
3) Respiratory failure- o.1mg/kg IVP max 4mg
Term
Midazolam (Onset)
Definition
3-5 minutes dose dependent IV/IO
15 minutes IM
Term
Midazolam (duration)
Definition
2-6 hours dose dependent
Term
Midazolam (Pregnancy)
Definition
Category D
Term
Midazolam (Notes)
Definition
1) may cause apnea, esp, in children and elderly
2) effects intensified by ETOH and other CNS depressants
3) be prepared to support respirations
4) carefully monitor V/S including EKG & pulse Ox
5) 3 to 4 times stronger than Vallium
6) Use caution if MAP <70mmHg
Term
Nitro-Bid (aka)
Definition
Nitropaste, NTG
Term
Nitro-Bid (class)
Definition
Vasodilator
Term
Nitro-Bid (Actions)
Definition
1) Dilates arterial and venous vessels resulting in venous pooling
2) reduces preload and after load resulting in decreased myocardial workload and reduced oxygen demand
3) relaxes smooth muscle
4) dilates coronary vessels resulting in increased perfusion of the myocardium
5) relieves coronary vasospasm
Term
Nitro-Bid (indications)
Definition
Chest pain of suspected myocardial origin
Congestive heart failure/cardiogenic pulmonary edema
Term
Nitro-Bid (contraindications)
Definition
S/S of neurological deficit
SBP <100mmHg
Recent use of Viagra
Cialis
Levity within the last 24 hours
Term
Nitro-Bid (Adverse Reactions)
Definition
Hypotension, Nausea/Vomiting, Headache, Postural Syncopy
Term
Nitro-Bid (Dosage)
Definition
Nitro-paste 1" = 14mg
Term
Nitro-Bid (Onset)
Definition
1-3 minutes
Term
Nitro-Bid (duration)
Definition
20-30 minutes
Term
Nitro-Bid (pregnancy)
Definition
Category C
Term
Nitro-bid (Notes)
Definition
Healthcare provider may experience adverse effects if accidentally handled or absorbed
Use caution in patients with possible right ventricular infarct
Term
Pepcid (aka)
Definition
Famotidine
Term
Pepcid (class)
Definition
Histamine H2 - Receptor Antagonist
Term
Pepcid (actions)
Definition
Competitively inhibits the action of histamine at the histamine H2- receptors
The antihistamine property functions to inhibit gastric acid secretion, and to inhibit the action of histamine from contributing to anaphylactoid reactions and/or anaphylaxis.
Term
Pepcid (Indications)
Definition
1) Allergic/Anaphylactic Reactions: in adult and pediatric patients. Pepcid is indicated even in the presence of hypotension.
2) GI bleeding: in adult patients not to be used for pediatric GI bleeding
Term
Pepcid (contraindications)
Definition
Hypersensitivity
Term
Pepcid (Adverse Reactions)
Definition
Rare instances of arrhythmias and hypotension have been reported following rapid IV bolus.
Term
Pepcid (Dosages)
Definition
1) GI bleed 20mg slow IVP over 2 minutes.
2) Allergic reaction 20mg slow IVP or IM over 2 min.
3) Pedi Allergic reaction- 0.5mg/kg IVP slow over 2min. max 20mg
Term
Pepcid (precautions)
Definition
Admin. with a slow IVP over 2 minutes
Term
Pepcid (Onset)
Definition
within 1 hour
Term
Pepcid (Duration)
Definition
10-12 hours
Term
Pepcid (comments)
Definition
supplied as 20mg/2cc
Term
Pitressin (aka)
Definition
Vasopressin
Term
Pitressin (class)
Definition
antidiuretic; hormone
Term
Pitressin (actions)
Definition
Directly stimulates smooth muscle V1 receptors resulting in vasoconstriction
Term
Pitressin (indications)
Definition
Cardiac arrest
Term
Pitressin (contraindications)
Definition
Hypersensitivity
Term
Pitressin (adverse reactions)
Definition
1) Ischemic chest pain
2) ADB distress
3) N/V
4) Tremors
5) Bronchial constriction
6) Uterine contraction
7) sweating
Term
Pitressin (precautions)
Definition
1) Severe hepatic disease
2) seizure disorder
3) congestive heart failure
4) impaired kidney function
5) asthma
6) migraines
7) elderly patients
Term
Pitressin (dosages)
Definition
40 U IV/IO to be given sequentially in the first admin of Epi
Term
Pitressin (onset)
Definition
Immediate
Term
Pitressin (duration)
Definition
Variable
Term
Pitressin (Pregnancy)
Definition
Category C
Term
Sodium Bicarbonate (aka)
Definition
NaHCO3
Term
Sodium Bicarb (class)
Definition
Alkalinizing agent
Term
Sodium Bicarb (actions)
Definition
combines with hydrogen ions to form carbonic acid, increases blood pH
Term
Sodium Bicarb (indication)
Definition
Overdose of tricyclic antidepressants
Prolonged arrest
Term
Sodium Bicarb (contraindications)
Definition
Not significant in the above situation
Term
Sodium Bicarb (adverse reaction)
Definition
metabolic alkalosis
pulmonary edema
Term
Sodium Bicarb (precautions)
Definition
may deactivate vasopressors
Term
Sodium Bicarb (dosages)
Definition
PEA Bundle 1 amp
Crush Syndrome 50 mEq
Term
Sodium Bicarb (onset)
Definition
immediate
Term
Sodium Bicarb (duration)
Definition
30-60 minutes
Term
Sodium Bicarb (pregnancy)
Definition
Class C
Term
Sodium Bicarb (comments)
Definition
Flush IV tubing before and after admin
Term
Succinylcholine (aka)
Definition
Anectine
Term
Succ's (Class)
Definition
Neuromuscular blocker (depolarizing)
Term
Succ's (actions)
Definition
depolarizing neuromuscular block
Term
Succ's (indications)
Definition
Rapid muscle paralysis
Term
Succ's (contraindications)
Definition
1) Hypersensitivity
2) Hyperkalemia
3) Penetrating eye injury
4) Malignant hyperthermia
5) burns, multiple trauma and soft tissue >24 hrs old
6) suspected fractured larynx that prevents proper performance or sellick's maneuver
Term
Succ's (adverse reactions)
Definition
1) dysrhythmias
2) prolonged apnea
3) respiratory depression
4) bronchospasm
5) increase in serum potassium
6) ICP
7) inability to perform adequate neurological exam
Term
Succ's (precautions)
Definition
make sure all meds prepared prior to induction
Measures to control anxiety and pain must be utilized
Term
Succ's (dosages)
Definition
Adult- 1mg/kg max of 200mg
Term
Succ's (onset)
Definition
30-90 seconds
Term
Succ's (duration)
Definition
4-5 minutes
Term
Succ's (pregnancy)
Definition
Category C
Term
Succ's (comments)
Definition
1) if consistent and dramatic temperature rise is observed, use whatever means necessary to lower patients temperature
2) muscle relaxation order: eyelids-jaw-limbs-abdominals-diaphragm-intercostal muscles
3) NO EFFECT ON CONSCIOUSNESS
4) enhances by lidocaine, procainamide, beta-blockers, and mag sulfate
Term
Valium (aka)
Definition
Diazepam
Term
Valium (Class)
Definition
1) Benzodiazepine
2) CNS depressant
3) Non-barbituate sedative/hypnotic
4) anticonvulsant
5) anti-anxiety
Term
Valium (actions)
Definition
Act on the brain and nerves (central nervous system) to produce a calming effect
It works by enhancing the effects of certain natural chemicals in the body (GABA)
Term
Valium (indications)
Definition
Seizures, Status Epilepticus, Acute anxiety states, skeletal muscle relaxant, management of alcohol withdrawal
Term
Valium (contraindications)
Definition
Hypersensitivity
Use of other CNS depressants
Hypotension & various stated of shock
Term
Valium (adverse reactions)
Definition
Headache
Cardiac arrest
Respiratory Depression
Apnea and Hypotension
Dizziness, Ataxia, Fatigue, Confusion
Transient Drowsiness
Term
Valium (precautions)
Definition
Caution with hepatic dysfunction
Renal insufficiency or HX of drug addiction
Elderly/debilitated may require reduced dosage
Term
Valium (adult dosage)
Definition
Heat cramps 2.5mg IV r. X1 to 5mg max
Difficult Airway - may be substituted for Versed in 5mg increments slow IVP every 3-5 min. (max total 20mg)
Term
Valium (onset)
Definition
30-90 seconds
Term
Valium (duration)
Definition
15-60 minutes
Term
Valium (pregnancy)
Definition
Category D
Term
Valium (notes)
Definition
rectal valium should be followed by tylenol suppository if patient is febrile and if tylenol suppository is available via family
Term
Xopenex (aka)
Definition
Levalbuterol
Term
Xopenex (class)
Definition
Bronchodilator
Beta 2 adrenergic agonist
Term
Xopenex (actions)
Definition
stimulates beta 2 adrenergic receptors (selective beta agonist)
Term
Xopenex (indications)
Definition
Bronchospasm associated with restrictive airway disease including asthma and COPD
Term
Xopenex (contraindications)
Definition
Hypersensitivity to drug/class or components
MAO inhibitor use within 14 days
Not approved in children <6 yrs. age
Term
Xopenex (adverse reactions)
Definition
Paradoxical bronchospasms
Possible EKG changes (flattened T waves, prolonged QT interval, ST segment depression)
Term
Xopenex (precautions)
Definition
caution with arrhythmias, CAD, HTN
Term
Xopenex (dosages)
Definition
0.63mg q 5 minutes Max 3 doses
Term
Xoponex (onset)
Definition
5-15 minutes post inhalation
Term
Xoponex (duration)
Definition
3-4 hours
Term
Xoponex (comments)
Definition
not for use in children <6 yrs old
Term
Zofran (aka)
Definition
Odansetron
Term
Zofran (class)
Definition
anti-nausea
antiemetic
Term
Zofran (actions)
Definition
blocks serotonin, both peripherally on vagal nerve terminals and centrally in chemoreceptor trigger zone
Term
Zofran (indications)
Definition
patients experiencing nausea and vomiting
Term
Zofran (contraindications)
Definition
there are no absolute contraindications to the use of Zoran
Term
Zofran (adverse reactions)
Definition
Anxiety, Dizziness, Drowsiness, Headache, Fatigue, Constipation, Diarrhea, Hypoxia, Urinary retention
Occasionally may cause: ABD pain, fever, feeling of cold, paresthesia, weakness
Term
Zofran (precautions)
Definition
none
Term
Zofran (adult dosages)
Definition
N/V : 4mg IVP/IM
Hypertensive crisis: 4mg IVP or IM
Dysbarism & Decompression sickness: 4mg IVP/IM
Head Injury: 4mg IVP/IM
Pain Management after morphine- 4mg IVP or IM max of 8mg
Term
Zofran (pediatric dosage
Definition
N/V: 2mg IV or IM r. once if necessary q. 5 min. Mx 4mg
Term
Zofran (onset)
Definition
IV: rapid
IM: rapid
Term
Zofran (duration)
Definition
IV: 4-8 hours
IM: unknown
Term
Zofran (pregnancy)
Definition
Class B
Term
Zofran (comments)
Definition
Zoran may be given IM (undiluted) in absence of an IV
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