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PCB3063 Genetics
Exam 3
18
Biology
Undergraduate 1
11/07/2012

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Term
5'-3' Exonuclease
Definition
Removes Primers
Term
3'-5' Exonuclease
Definition
Proofreading
Term
Base excision repair
Definition
Repairs point mutations, cytosine deamination, depurinated sites

Fxnl Enzymes:
Base-specific DNS Glycosylase
AP endonuclease
Term
Nucleotide excision repair
Definition
Repairs bases with large side groups and thymine dimers- things that disort the double helix

Fxnl Enzymes:
UVR genes
Term
Mismatch repair
Definition
Repairs wrong base in DNA, slippage

Fxnl Enzymes: Mut HLS
Term
Recombination repair
Definition
Repairs gaps in DNA, broken strands

Fxnl Enzymes: recA
Term
DNA Polymerase I
Definition
Removes primers, fills gaps, DNA repair
Term
DNA Polymerase II
Definition
DNA repair
Term
DNA Polymerase III
Definition
Synthesizes the leading and lagging strands
Term
Repetitive DNA sequences make up ___________ percent of the eukaryote genome.
Definition
40-60
(5-10 Simple Sequence/Satellite
40 Transposable/Interspersed)
Term
Satellite DNA
Definition
Centromeres, Telomeres
Term
Heterochromatin
Definition
Condensed, Methylated
Term
Euchromatin
Definition
Uncondensed, Acetylated
Term
RNA Polymerase
Definition
NO PRIMER NEEDED, binds to promoter
Term
mRNA
Definition
codon
Term
tRNA
Definition
anticodon
Term
Shine Dalgarno
Definition
indicates start codon in bacteria, small subunit binds to SD
Term
Kozak sequence
Definition
Surrounds start codon in eukaryotes, small subunit attaches to 5' cap and slides down to start codon, 5' cap needed for initiation of translation
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