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PBD Test 3
UFCOP
29
Medical
Graduate
10/27/2008

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Cards

Term
The upper respiratory tract is made up of what 7 parts?
Definition
Nares, nasal cavities, nasal conchae, nasal mucosa, pharynx, eustachian tube, and the sinuses.
Term
What is a word that describes speech?
Definition
Phonation
Term
What blocks food from entering the trachea?
Definition
Epiglottis (covers the glottis)
Term
What are the 8 functions of the airways?
Definition
Filtering, warming, humidifying, turbulent precipitation, sneeze reflex, gag reflex, cough reflex, and swallow reflex.
Term
The lower respiratory tract is made up of what three parts?
Definition
Larynx, tracheobronchial tree, and the trachea.
Term
The sharp point present where one airway branches into two is called what?
Definition
Carina
Term
Name the three types of cells in the trachea and their function.
Definition
Basal cells- Divide to replace cells
Goblet cells- secrete mucous
Ciliated cells- propel mucous
Term
Where does gas exchange not take place in the airways (from what to what)? What generation is this? What is the width at the end? How much anatomical dead space is there?
Definition
-Nose to terminal bronchioles (conducting airways)
-Generation 16
-0.6-1mm
-150 mL
Term
Which generations have alveoli budding off? What generations?
Definition
Respiratory Bronchioles
Generations 17-19
Term
What part of the airways is completely lined with alveoli? What generations?
Definition
Alveolar Ducts
Generations 20-22
Term
What part of the airways contains groups of alveoli? What generations?
Definition
Alveolar Sacs
Generation 23
Term
What regulates bronchomotor tone? What does stimulation cause?
Definition
Parasympathetic Nervous System

Stimulation causes constriction
Term
What do vagal fibers activate on and in the airway wall?
Definition
Nicotinic receptors in parasympathetic ganglia
Term
What does short postganglionic fibers release and stimulate on airway smooth muscle cells?
Definition
Release- ACh
Stimulate- M3 Muscarinic Receptors
Term
What endogenous compound causes dilation of the airways and where is it mainly released from?
Definition
Epinephrine and Norepinephrine released from adrenal medulla
Term
What are three treatments of bronchoconstriction?
Definition
Anticholinergic Agents (atropine, scopolamine)
B2 adrenergic agonists (albuterol turbutaline)
Antiinflammatory agents (glucocorticoids)
Term
What are three treatments of airway hypersecretion?
Definition
Belladonna alkaloids in nose, mouth, pharynx, and bronchi
Atropine/scopolamine used in preanesthetic medication
Term
What may have side effects in patients with airway disease?
Definition
Atropine/scopolamine
Term
Describe alveoli: how many, diameter, surface area, and shape.
Definition
-Avg. 300 million
-0.25-0.33 mm in diamter
-Avg. 80 m^2
Term
Name the 6 things gas must pass through in the blood-gas barrier and what is its avg. thickness?
Definition
<0.5 um
1. Surfactant
2. Alveolar epithelium (type 1 pneumocytes)
3. Interstitium
4. Capillary endothelial cells
5. Plasma
6. Erythrocyte cell membrane
Term
What type of pneumocyte secretes surfactant? What is the chemical name for surfactant? Which pneumocytes are more numerous?
Definition
-Type II secretes surfactant
-Dipalmitoyl lecithin
-Type II are more numerous
Term
What is the rate of lymphatic drainage?
Definition
2 mL/min
Term
What is the most frequent disease and what is the leading cancer killer?
Definition
-Respiratory infections most common diseases
-Lung cancer is leading cancer killer
Term
Describe early cough diseases.
Definition
Those involving the mucosa or generating secretions; localized
Term
Describe early dyspnea diseases. Is dyspnea typically chronic or acute?
Definition
Those that interfere with gas exchange; diffuse.

Dyspnea typically chronic
Term
What is caused by the inhalation of mineral or organic dust? What types of pneumoconiosis are there?
Definition
Pneumoconiosis

Silicosis and asbestosis
Term
What are the two types of bacterial pneumonias? Describe each.
Definition
Lobar- involvement of entire lobe; pneumococci (90% of lobar), klebsiella, saphylococcal

Bronchopneumonia- patchy areas of involvement; usually follows bronchitis, usually threat is to the vulnerable, caused by any organism, complications common
Term
What are 6 types of viral pneumonia causes?
Definition
Mycoplasma pneumoniae
Influenza A and B
Parainfluenza
RSV
ECHO viruses
Varicella
Term
Is pneumonia considered a chronic or acute cough? Bronchiectasis?
Definition
Pneumonia is an acute cough and bronchiectasis is a chronic cough.
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