Fibroadenoma of the Breast

Note compressed lactiferous ducts

Serous Cystadenocarcinoma

Here is a benign serous cystadenoma that demonstrates multiloculation. Note that the inner surface is, for the most part, smooth, with only a solitary papillation at the upper right.

Serous Cystadenocarcinoma

Ovarian papillary serous cystadenocarcinomas may contain small concretions called psammomma bodies, seen here as purplish rounded and laminated objects. They are essentially just a form of dystrophic calcification in neoplasms.

Medullary Carcinoma

At the center and to the right is a medullary carcinoma of thyroid. At the far right is pink hyaline material with the appearance of amyloid. These neoplasms are derived from the thyroid "C" cells and, therefore, have neuroendocrine features such as secretion of calcitonin

Pituitary Adenoma

The circumscribed mass lesion present here in the sella turcica is a pituitary adenoma. Though pituitary adenomas are benign, they can produce disorders either from a mass effect (usually visual problems from pressing on the optic chiasm and/or headaches) or from production of excess of hormones such as prolactin or ACTH.

Graves Disease

Tall columnar thyroid epithelium with Graves disease lines the hyperplastic infoldings into the colloid. Note the clear vacuoles in the colloid next to the epithelium where the increased activity of the epithelium to produce increased thyroid hormone has led to scalloping out of the colloid.

Graves Disease

A diffusely enlarged thyroid gland associated with hyperthyroidism is known as Graves disease. At low power here, note the prominent infoldings of the hyperplastic epithelium. In this autoimmune disease the action of TSI's predominates over that of TGI's

Endometriosis

Endometrial glands and stroma are seen at high magnification in the wall of the colon. Endometriosis is symptomatic during reproductive years when patients may present with dysmenorrhea, pelvic pain, and infertility.

Endometriosis

Grossly, in areas of endometriosis the blood is darker and gives the small foci of endometriosis the gross appearance of "powder burns". Small foci are seen here just under the serosa of the posterior uterus in the pouch of Douglas.Such areas of endometriosis can be seen and obliterated by cauterization via laparoscopy

Leiomyosarcoma

Microscopic appearance of a leiomyosarcoma. It is much more cellular and the cells have much more pleomorphism and hyperchromatism than the benign leiomyoma. An irregular mitosis is seen in the center

Leiomyosarcoma

A leiomyosarcoma protruding from myometrium into the endometrial cavity of this uterus that has been opened laterally so that the halves of the cervix appear at right and left. Fallopian tubes and ovaries project from top and bottom. The irregular nature of this mass suggests that is not just an ordinary leiomyoma

Ovarian Dysgerminoma

This is an ovarian dysgerminoma that has been sectioned into two halves. Note the pale brown appearance of the parenchyma, along with some central collagenous scar. The gross and microscopic appearance of an ovarian dysgerminoma is essentially the same as a seminoma of the testis in a male.