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Pathophysiology
chps:1,2,3
57
Physiology
Professional
08/24/2010

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Term
Prokaryotes
Definition
Nucleus-single circular chromosomes
lacks histones
Ex: cyanobacteria, bacteria, and rickettsiae
Term
Eukaryotes
Definition
complex cellular organization
-membrane-bound organelles
-well-defined nucleus
-ex: higher animals, plants, fungi, protozoa, and algae
Term
What does the nucleus in the eukaryotic cell consist of ?
Definition
-nuclear envelope
-nucleolus
-DNA ( dna replication, repair, and transcription
-histone proteins
-cell division
Term
What does the eukaryotic cytoplasm consist of ?
Definition
cytoplasmic matrix
-cytosol
-function
-cytoplasmic organelles
Term
What are two eukaryotic organelles?
Definition
ribosomes and endoplasmic reticulum
Term
What is the ER?
Definition
-site of protein synthesis
Term
what are ribosomes?
Definition
-RNA protein
-free ribosomes
-attached ribosomes
Term
what does the Golgi complex consist of ?
Definition
flattended, smooth membranes
-secretory vesicles
-proteins from the ER are packaged in the Golgi complex
-cisternae
Term
What are lysosomes and where do they come from?
Definition
originate from the golgi and catalyze proteins, lipids, nucleic acids, and carbohydrates
-role in autodigestion
Term
what are peroxisomes? Are they located in Eukaryotic orgganelles or Prokaryotic?
Definition
they are located in eukaryotic organelles and they contain oxidative enzymes and break substances down into harmless products
Term
What is the mitochondria?
Definition
-located in eukaryotic organelle
-surrounded by a double lipid bilayer membrane
-participates in oxidative phosphorylation
-increased inner membrane surface area provided by cristae
Term
what are vaults?
Definition
they are cytoplasmic ribonucleoproteins, shaped like octagonal barrels
-cellular trucks
-located in eukaryotic organelles
Term
What are considered the bones and muscles of the cell? List some other important characteristics.
Definition
cytoskeleton
-maintains the cell's shape and internal organization
-permits movement of substances within the cell and movement of external projections
-microtubules (centrioles)
-microfilaments
Term
Plasma membrane
Definition
-controls the composition of a space or compartment they enclose
Term
what does the structure of the plasma membrane consist of?
Definition
- caveolae
-lipids
-carbohydrates
-proteins????
Term
what do the lipids consist of?
Definition
amphipathic lipids
-phospholipids, glycolipids, and cholesterol
Term
what are amphipathic lipids?
Definition
hydrophilic and hydrophobic
Term
what do the carbohydrates consist of?
Definition
glycoproteins
Term
What are the important proteins that are important to the plasma membrane?
Definition
-integral, peripheral, transmembrane
Term
what are integral proteins?
Definition
embeded in plasma membrane
Term
what are transmembrane proteins?
Definition
extracellular thru intracellular
Term
what are peripheral proteins?
Definition
allow extracellular space
Term
What are the types of cellular receptors?
Definition
ligands
plasma membrane receptors
Term
Look at cell-to cell adhesions
Definition
Term
what are the types of cell junctions?
Definition
desmosomes, tight junctions, gap junctions...considered a type of cell-to-cell adhesion
Term
Refer to cellular communication
Definition
Term
what types of chemical signaling exist?
Definition
hormonal,neurohormonal, paracrine, autocrine autostimulation
Term
what is neurohoromonal?
Definition
hormones released from neurosecretory neurons into blood
Term
what is paracrine?
Definition
secrete local chemical mediators that are quickly taken up, destroyed or immobilized
Term
what is autocrine-autostimulation?
Definition
components of normal growth
Term
Neurotransmitter
Definition
-secreted by neurons
-fast travel to chemical synapses
Term
look at signal transduction
Definition
Term
convey instructions to the cell's interior
(transfer, amplify, distribute, and modulate)
Definition
extravellular messengers
Term
what are the types of signal transduction?
Definition
extracellular messengers
-channel regulation
-second messengers
Term
what are the two pathways for second messengers?
Definition
-cyclic adenosine monophosphate (cAMP)
-Ca++
Term
what is metabolism?
Definition
chemical tasks of maintaining essential cellular functions
Term
what is anabolism?
Definition
build up something-(enery using)
Term
what is catabolism?
Definition
break down (enery releasing)
Term
Adenosine Triphosphate
Definition
-used in synthesis of organic molecules, muscle contraction, and active transport
-stores and transfers energy
-created from the chemical energy contained within organic molecules
Term
what are some important components of cellular enenrgy or examples?
Definition
-digestion
-glycolysis
-citric acid cycle
-oxidative phosphorylation
Term
what is glycolysis?
Definition
-occurs in the cytoplasm
-anaerobic
Term
what is an alternative name or names for citric acid cycle?
Definition
-Krebs cycle or tricarboxylic acid
Term
what is oxidative phosphorylation?
Definition
-occurs in the mitochondria
-aerobic glycolysis (citric acid cycle)
-requires ATP
Term
what is passive transport?
Definition
net movement of molecules and ions across a membrane from higher to lower concentration( down a concentration gradient) does not require metabolic enery.
Term
what does passive transport include?
Definition
simple diffusion, osmosis, and facilitated diffusion
Term
What is active transport?
Definition
net movement across a membrane that occurs against a concentration gradient (to the region of higher concentration).
Term
what does active transport require?
Definition
expenditure of ATP and involves specific carrier proteins
Term
what is resting membrane potential?
Definition
-inside of cell is negatively charged in comparison to the outside of cell (ex: in neurons usually is -70mv)
Term
what is repolarization?
Definition
a return to resting membrane potential
Term
If stimulation causes the inside of the cell to become more negative than the resting membrane potential, the oscilloscope will deflect downward. this is called what?
Definition
hyperpolarization
Term
If appropriate stimulation causes positive charges to flow into the cell, the line will deflect upward. this is called what?
Definition
depolarization (hypopolarization)
Term
what is mitosis?
Definition
cell division in which the two daugter cells receive the same number of chromososomes as the parent cell (both daughters and parent are diploid)
Term
Is G2 phase longer or shorter than G1?
Definition
shorter
Term
what is the cell cycle?
Definition
interphase(g1,s, g2)
-mitosis (pmat-prophase,metaphase,anaphase,telophase)
-cytokinesis
Term
review the cell cycle
Definition
Term
what are some influences on the cell cylce?
Definition
cellular division rates and growth factors
Term
review types of tissues
Definition
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