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Pathophysiology
altered cellular and tisssue biology
32
Pathology
Graduate
01/11/2010

Additional Pathology Flashcards

 


 

Cards

Term

 

 

 

Acidemia

Definition

 

 

 

 

a state in which the pH of artrial blood is less than 7.35.

Term

 

 

 

 

intracellular fluid (ICF)

Definition

 

 

 

2/3 of the body's water

Term

 

 

 

extracellular fluid (ECF)

Definition

 

 

 

1/3 of the body's water

Term

 

 

 

the two main ECF compartments

Definition

 

 

 

interstitial fluid

 

intravascular fluid

Term

 

 

 

 

intravascular fluid

Definition

 

 

 

the blood plasma

Term
Aquaporins
Definition

 

 

a family of water channel protiens that provide permeability to water at the capillary membrane

Term
net filtration
Definition
the movement of fluid back and forth across the capillay wall
Term
Starling hypothesis
Definition
Net filtration= (forces favoring filtration) - (Forces opposing filtration)
Term
edema
Definition
the accumulation of fluid within the interstitial spaces
Term
lymphedema
Definition
proteins and fluid accumulate in the interstital space
Term
osmoreceptors
Definition
neurons located in the hypothalmus that are stimulated by increasing osmolality
Term

volume-sensitive receptors

and

baroreceptors

Definition
nerve endings that are sensitive to changes in volume and pressure
Term
chloride
Definition
the major anion in the extracellular fluid
Term
aldosterone
Definition
mineralocorticoid synthesized and created from the adrenal cortex.  it is secreted when the sodium levels are depressed, potassium levels are increased or renal profusion is decreased.  It increases the reabsorption of sodium and secretion of potassium
Term
renin
Definition

an enzyme secreted by the juxtaglomerular cells of the kidney, is released in response to sympathetic nerve stimulation and decreased perfusion of the renal vasculature.  stimulates the formation of angiotensin

1

Term
angiotensin 1
Definition
an inactive polypeptide which turns into angiotensin II
Term
angiotensin II
Definition
two major functions: stimulates the secretion of aldosterone, causes vasoconstriciton
Term
renin-angiotensin system
Definition
the sodium and water regulation mechanism
Term
natriuretic peptides
Definition
hormones produced by the heart, brain and kidney and work to decrease blood pressure and increase sodium and water excretion
Term
isotonic volume depletion
Definition
causes contraction of the ECF volume with the resulting weight loos, dryness of skin and mucous membranes, decreased urine output, symptoms of hypovolemia
Term
Isotonic volume excess
Definition
most commonly caused by excessive administration of
IV fluids, hyper-secretion of aldosterone, or the effects of drugs such as cortisone
Term
hypernatremia
Definition
occurs when serum sodium levels exceed 147 mEq/L. may be caused by an acute gain in sodium or loss of water.
Term
hyperchloremia
Definition
greater than normal amounts of chloride in the blood, can be expected with hypernatremia or metabolic acidosis
Term
hyponatremia
Definition
sodium deficit in the blood
Term
pure sodium deficits
Definition
usually caused by diuretics and external losses such as vomiting, diarrhea, gastrointestinal suctioning or burns
Term
dilutional hyponatremia
Definition
occurs when there is an excess of TBW in relation to total body sodium or a shift of water from the ICF to ECF space. hypotonic fluid, mannitol, or excessive sweating can cause
Term
dilutional hyponatremia
Definition
occurs when there is an excess of TBW in relation to total body sodium or a shift of water from the ICF to ECF space. hypotonic fluid, mannitol, or excessive sweating can cause
Term
Acute orthostatic hypotension
Definition
Term
acute pericarditis
Definition
Term
adducin
Definition
Term
aneurysm
Definition
Term
angina pectoris
Definition
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