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Pathophysiology
Ch 3 continued
29
Health Care
Undergraduate 2
09/03/2008

Additional Health Care Flashcards

 


 

Cards

Term
Systemic Manifestations
Definition
Fever
Tachycardia
Leukocytosis
• Pain
Term
Cellular accumulations
Definition
Water
Lipids and Carbohydrates Glycogen
Proteins
Pigments
Calcium
Urate
Term
Asphyxial injuries
Definition
failure of the cells to receive or utilize oxygen
Term
Laceration
Definition
tear or rip skin (common with the elderly)
Term
Chemical Mechanism of Cellular injury: Mercury
Definition
Dental amalgams
Fish consumption
Vaccines
Term
Fetal Alcohol Syndrome
Definition
Microcephaly- small brain
Low birth weight
Cardiovascular defects
Developmental disabilities
Physical- sm head and features
Mental- decreased cognition speech problems, retardation at different levels.
Term
Mechanisms of Cellular Injury: Chemical
Lead
Definition
alters nervous system and affect Ca(affects clotting factors- bleeding).
Term
Free Radicals Cause damage by
Definition
Lipid peroxidation(Failure of Na-K pumps)-destruction of polysaturated lipids; changes permeability.
• Attacking critical proteins- no nutritional source; delayed wound healing.
Fragmenting DNA- cannot create proteins(essential to life).
Damaging mitochondria- damages the powerhouse(no ATP prod)
Term
Hypoxic injury
Definition
in sufficient oxygen
Term
Anoxia
Definition
total lack of oxygen
Term
Reperfusion injury
Definition
oxygen restored to the cell, but not to function normally causing permanent injury.
Term
Atrophy
Definition
cells are shrinking (not decreasing in #)
Term
Physiologic Atrophy
Definition
normal shrinking; thymus shrinks to nothing during childhood.
Term
Pathologic Atrophy
Definition
cells are shrinking; abnormal response because of…decreased workload, increase in pressure, low blood supply ect…
Term
Atrophy Disuse(muscles)
Definition
cells are shrinking-no use of muscle (in a cast, paralysis)
Term
Hypertrophy
Definition
cells increase in size
Term
Hypertrophy Physiologic
Definition
cells increase in size-normal increase; body builder
Term
Hypertrophy Pathologic
Definition
cells increase in size-abnormal response; heart enlarged due to increased workload (hypertension).
Term
Hyperplasia
Definition
increase in # of cells
Term
Hyperplasia Compensatory
Definition
increase in # of cells(regeneration) physiologic response to maintain body function.
Term
Hyperplasia Hormonal
Definition
increase # of cells in hormonal dependent organs ( ex. Estrogen during pregnancy)
Term
Dysplasia
Definition
cell changes and no longer functions as a cell, changes composition.
Term
Metaplasia
Definition
adaptive response; (reversible) changes cell type in response to an irritant; will revert to normal once irritant is removed.
Term
Necrosis
Definition
localized cell death
Term
cellular dissolution
Definition
breakdown of cells
Term
autolysis
Definition
breakdown of protein and enzyme
Term
Coagulative Necrosis: Occurs & Characteristics
Definition
Occurs: Kidneys, heart, adrenal glands; Appearance: gelatinous, transparent state to a firm, opaque state
Term
Liquefactive Necrosis: Cause & Characteristics
Definition
Patho: Bacterial infection staphylococci, streptococci, and Escherichia coli; Appearance: tissue soft, liquefies, and walled off from healthy tissue, forming cysts
Term
Caseous Necrosis: cause and characteristics
Definition
COMBO infection caused by Mycobacterium tuberculosis;Appearance: tissues resemble cottage cheese; inflammatory wall encloses areas of caseous necrosis
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