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Pathophysiology - Test 1
Introduction thru Endotoxin
24
Pathology
02/09/2010

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Term
Concept of disease
Definition
Pathological condition of a part, organ, or system resulting from various causes such as infection genetic defect and environmental stress. characterized by an identifiable group of signs or symptoms
Term
Abnormal vs. Normal Process
Definition
represent different points on same spectrum. Seeds of disease often lie within adaptive mechanism of body itself. Double edged sword.
Term
Individual norms
Definition
a single measurement, observation, or lab result that indicates abnormality. must always be judged in the context of the entire situation of the individual
Term
Group norms
Definition
average values for height, weight, and BP. derived from observations of many individuals.
Term
Define eitiology
Definition
study of cause or origins. this is the branch of medicine that deals with the causes or origins of disease.
Term
4 types of Cellular injury
Definition
oxygen decrease, physical (gun), living agent (bac. or vir), & chemical (CO)
Term
How cells under attack adapt
Definition
Edema happens first. Water and fat (LHK) retention happens. Interferons released.
Term
Most common forms of cellular degenerative change
Definition
Swelling with water in the cytoplasm (save HLK. Sometimes injuries will become malignant.
Term
Autophagocytosis
Definition
Degenerative change. process of phagocytizing a portion of protoplasm by vacuole within the cell. Liver spots are a good example.
Term
Relationship between cellular death and acute inflammatory disase
Definition
When cells die they release an enzyme that starts the cleaning up process. this adjunct tissue response is called inflammation.
Term
Necrotic
Definition
Premature death of cells and living tissue from irreversible damage
Term
Coagulative necrosis
Definition
Tissue still retains architectural shape (toe of a diabetic)
Term
Liquefactive Necrosis
Definition
Tissue liquefies and is no longer there (brain tissue post stroke)
Term
Casseous Necrosis
Definition
Cavity forming. Tb causes this in the lungs.
Term
Gangrene
Definition
Infected necrotic tissue
Term
Dytrophic calcification
Definition
Calcium deposits in places where it should be. Lungs and arteries & sometimes particular disease (pigeons)
Term
Rigor Mortis
Definition
Stiffening of muscles post somatic death
Term
Algor Mortis
Definition
Cooling of body post somatic death. (Checked in liver)
Term
Livor Mortis
Definition
Pooling of blood post death. Gravity driven
Term
Extrinisic Factors
Definition
Come from the outside. Examples are bacteria, trauma, & environmental chemicals.
Term
Intrinsic Factors
Definition
Come from the inside. Age, gender & genetics
Term
Genetic diseases
Definition
Have identified a specific gene that causes problem (ex. Downs Syndrome)
Term
Congenital diseases
Definition
Problems evident at birth. Not always genetic (Fetal Alcohol)
Term
Familial Diseases
Definition
Affects members of same family without necessarily being inherited. Obesity may be linked to eating MCD everyday.