Shared Flashcard Set

Details

Pathology 678 - 734
Robbins and Cotran
30
Pathology
Graduate
02/23/2011

Additional Pathology Flashcards

 


 

Cards

Term
Right Bronchus differential anatomy
Definition
Right bronchus is more vertical, higher, and parallel to trachea
Term
Levels of Bronchial Tree
Definition
Bronchi, bronchioles, terminal bronchioles, acinus, respiratory bronchioles, alveolar ducts/sacs.
Term
Bronchioles
Definition
Divide from bronchi, lack cartilage and submucosal glands, lead to terminal bronchioles
Term
Acinus
Definition
Distal to terminal bronchioles. Made of respiratory bronchioles.
Term
Pulmonary Lobule
Definition
cluster of three to five terminal bronchioles. Important in distinguishing forms of emphysema.
Term
Type 1 pneumocytes
Definition
95% by area. Produced by type 2
Term
Type 2 pneumocytes
Definition
rounded cells that synthesize surfactant contained in lamellar bodies
Term
Pores of Kohn
Definition
permit passage of bacteria and exudate between adjacent alveoli
Term
Foregut Cysts
Definition
abnormal detachment of primitive foregut, often in hilum. Bronchogenic, esophageal, enteric.
Term
Pulmonary sequestration
Definition
discrete mass of lung tissue without normal connection to the airway system.
Term
Extralobar sequestrations
Definition
external to the lung. Associated with other developmental abnormalities
Term
Intralobar sequestrations
Definition
within lung substance in older children and often associated with infection or bronchiectasis
Term
Atelectasis
Definition
Collapse of lung.
Term
Resorption atelectasis
Definition
complete obstruction of an airway without impaired blood flow. Mediastinum shifts ipsilaterally. Caused by secretions or exudates.
Term
Compression atelectasis
Definition
Pleural cavity is partially or completely filled. Includes tension pneumothorax. Mediastinum shifts contralaterally.
Term
Contration Atelectasis
Definition
local or generalized fibrotic changes prevent full expansion
Term
Hemodynamic Pulmonary Edema
Definition
Most common. Often increased hydrostatic pressure. Often dependent edema. heart failure cells, brown induration, risk of infection
Term
Heart Failure Cells
Definition
Hemosiderin-laden macrophages
Term
Brown induration
Definition
Heart failure cells and fibrosis cause a firm brown lung
Term
ALI
Definition
Acute lung injury
Term
Acute Lung Injury
Definition
Acute Respiratory Distress Syndrome is most severe: Diffuse Alveolar Damage, abrupt hypoxemia. waxy hyaline membranes in alveoli. Type 2 pneumocytes proliferate.
Term
Obstructive Lung Diseases
Definition
increase resistance to airflow, decreased maximal airflow rates. Include emphysema, chronic bronchitis, asthma, bronchiectasis
Term
COPD
Definition
Includes emphysema and bronchitis. Often has a reversible 'asthema' component. Enlarged pores of Kohn, upper two thirds more severely affected.
Term
Restrictive Lung Disease
Definition
Reduced expansion of lung, reduced total lung capacity. Generally caused by chest wall disorders or chronic infiltrative diseases
Term
Emphysema
Definition
Irreversible enlargement of the airspace distal to the terminal bronchiole. Smokers, women, African Americans. Includes centriacinar, panacinar, distal acinar and irregular.
Term
Centriacinar Emphysema
Definition
(centrilobular): central or proximal parts of the acini are affected whereas distal alveoli are spared. More severe in upper lobes. Black pigment
Term
Panacinar Emphysema
Definition
(panlobular): acini are uniformly enlarged. More commonly in the lower zones and in the anterior margins. Associated with alpha1-AT deficiency`
Term
Distal Acinar Emphysema
Definition
(paraseptal): proximal portion of the acinus is normal. adjacent to areas of fibrosis, scarring or atelectasis. Often upper half of the lungs. Often cystlike structures and spontaneous pneumothorax
Term
Irregular Emphysema
Definition
(Airspace Enlargement with Fibrosis): Acinus is irregularly involved. associated with scarring.
Term
Histologic COPD changes
Definition
Goblet Cell Metaplasia, Inflammatory infiltration, smooth muscle hypertrophy.
Supporting users have an ad free experience!