Shared Flashcard Set

Details

Patho
Chapter 6
13
Nursing
Undergraduate 3
06/13/2010

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Cards

Term
What recognize specific antigens?
Definition
lymphocytes
Term
What type of cells are involved in humoral immunity?
Definition
B cells/B lymphocytes; B cells converted to plasma cells which produce antibody
Term
What type of cells are involved in cell-mediated immunity?
Definition
T cells
Term
What 3 ways can active (aquired) immunity occur?
Definition
by natural exposure to an antigen (body will produce its own antibodies), immunization, or bone marrow transplant
Term
Where are T cell receptors located?
Definition
on all types of T cells except Natural killer cells
Term
T cells are important in protection against what?
Definition
viruses, tumors, and pathogens that are resistant to killing by normal neutrophils and macrophages
Term
Class I MHC binds to antigens in what part of the cell?
Definition
ER
Term
On what cell is CD8 located and to what does it bind?
Definition
CD8 is found on the surface of a cytotoxic T cell and binds to Class I MHC
Term
What MHC Class is endogenous antigen processing associated with?
Definition
Class I MHC
Term
What MHC Class is exogenous antigen processing associated with?
Definition
Class II MHC
Term
On what cell is CD4 located and to what does it bind?
Definition
CD4 is located on helper T cells and binds to Class II MHC
Term
Where are Class I MHC found?
Definition
on ALL nucleated cells and platelets
Term
Where are Class II MHC found?
Definition
on B cells, APCs, and some epitheliel cells
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