Term
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Definition
| released from mast cells and basophils, causes vasodilation & bronchoconstriction |
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Term
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Definition
| released from platelets. increases vasodilation. |
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Term
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Definition
| increases vasodilation and perception of pain in that area. |
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Term
| Prostaglandins/Leukotrienes |
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Definition
| come from cell membranes being damaged. Arterioles open up & increase vascular permeability. |
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Term
| Platelet Activating Factor |
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Definition
| additional vasoactive mediator. (activated platelets) |
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Term
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Definition
| C5a- complement proteins-engulf debris |
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Term
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Definition
| Neutrophils-engulf as much tissue as it can then dies there. |
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Term
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Definition
| Pieces of cells rush to the area to plug up damaged capillary to limit loss of blood. |
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Term
| Monocyte becomes this once outside the vessel/in the interstitial fluid |
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Definition
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Term
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Definition
| consist of B & T cells depending on cause of CHRONIC inflammation |
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Term
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Definition
| make antibodies by B cells |
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Term
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Definition
| these guys lay down collagen for repair. |
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Term
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Definition
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Term
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Definition
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Term
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Definition
| acts as a stop cock for hemodynamic changes |
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Term
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Definition
| short lived-seconds to minutes, controlled by sympathetic discharge. |
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Term
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Definition
| hyperemia; overriding effect is arterioles open wide. |
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Term
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Definition
| contract opening junctions between the cells known as tight junctions. Inc. vasc. perm. |
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Term
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Definition
| leak out, resulting in a reduced capillary osmotic pressure, increased interstitial osmotic pressure. (inc. vasc. perm.) |
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Term
| Increased Vascular permeability |
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Definition
| increases the stasis & congestion of RBC's & WBC's |
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Term
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Definition
| pure water coming across endothelial cells |
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Term
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Definition
| plasma proteins and water leaking out |
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Term
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Definition
| RBC's, plasma proteins & water present in interstitium |
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Term
| Vasoactive Substance (Plasma Derived) |
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Definition
| Hageman clotting factor 12 & complement usually float around in blood in an inactive form. |
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Term
| Vasoactive substance (Cell Derived) |
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Definition
| Mast cells, basophils, platelets, PMN's, monocytes/macrophages. |
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Term
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Definition
| a compound released in the blood in some circumstances that causes contraction of smooth muscle and dilation of blood vessels. It is a peptide comprising nine amino-acid residues. |
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Term
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Definition
| antibody attaches to a cell and inserts a channel. |
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Term
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Definition
| destruction of the fatty tails leads to the formation of ______________. Also precursor to prostaglandins & leukotrienes |
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Term
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Definition
| are slow acting substances of anaphylaxis |
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Term
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Definition
| Leave the blood and go into tissue to become Mast cells. |
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Term
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Definition
| vasodilation, endothelial contraction, Bronchoconstriction, & mucus secretion |
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Term
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Definition
| cause trauma leading to Ca influx which leads to exocytosis (release) of histamine. |
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Term
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Definition
| molecule that acts as a binding enhancer to facilitate phagocytosis during the breakdown of necrotic tissue. |
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Term
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Definition
| Fibroblasts & macrophages by chemotaxis to healing tissue. |
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Term
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Definition
| secreted in abundance by fibroblasts early during the tissue repair rxn. |
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Term
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Definition
| bind to fibronectin & collagen to help stabilize tissue undergoing repair. |
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Term
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Definition
| support, protection, nourishment, innervation |
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Term
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Definition
| Glue producer, also the most abundant protein in the body. Provides structural support * tensile strength for almost all tissues & organs of the body |
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Term
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Definition
| most common form—very strong form and can be found in all body tissues. It is the main component of mature scars & abundant in strong tissues such as tendons & bones |
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Term
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Definition
| predominant type found in cartilaginous tissue. In the annulus of the disc, it has a ½ life of 3 months; allowing for maintenance of nutritive exchanges possibly delaying further degeneration |
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Term
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Definition
| accounts for plasticity of skin & blood vessels. Elastic; strong but supple. It contains interchain disulfide bonds. It is the 1st type deposited in wound healing. More prevalent in newborns. |
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Term
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Definition
| the development of new blood vessels. |
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Term
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Definition
| enhances wound tensile strength & is the main component of the scar tissue that remains after repair is completed. |
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Term
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Definition
| type III collagen is laid down first in an angiogenesis supported wound. As time passes type III is degraded by enzymes secreted by fibroblasts & is replaced by type 1 collagen. |
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