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Path IM HTN
KYCOM Block 13
49
Medical
Graduate
01/24/2014

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Cards

Term
define HTN
Definition
repeated reproductable measurement of BP >90/140
most common cardiovascular disease
+2 properlly measured, seated, BP readings on 2+ office visits
Term
general risk factors of HTN 11
Definition
smokng
contraception
hyperlipidemia
diabetes
obesity BMI 30
sedentary
microalbuminemia GFR <60mL/min
age men >45 women >55
family hx premature CVD men <55 women <64
race
education
Term
what are the two types of HTN, their definition, their prevelance
Definition
primary/essential 95%: no specific medical cause, normal CO

secondary 5%: result of another condition
Term
6 risk factors for essential HTN
Definition
HTN parents
Na intake
alcohol intake
obesity
hispanic, AA
hostile attitude, impatience, urgency
Term
clinical clues for secondary HTN 4
Definition
severe or refractory HTN acute rise in BP <30 yo in non-obese pt with no family hx proven onset 50yo
Term
causes of secondary HTN 7, most common in adults and kids
Definition
renal: most common overall
oral contraceptives
pheochromocytoma
primary hyperaldosteronism
cushing syndrome
coarctation of aorta (vessel wall compression): most common in kids
sleep apnea
Term
4 renal diseases causing secondary HTN:, which are most common in elderly, young, female
Definition
fibromuscular dusplasia: most common in young and obese females
renal artery stenosis
atheromatous disease: most common in elderly
primary renal disease
Term
how foes fibromuscular dysplasia cause HTN, how is it diagnosed
Definition
renal HTN leads to HTN
seen as string of beads on CTA/MRA
Term
how does renal artery stenosis cause HTN
Definition
increases renin from ischemic kidney, aNG II causes vasoconstriction, ALD increases blood volume
Term
how is primary renal disease diagnosed
Definition
elevated CR
abnormal urine analysis
Term
how does pheochromocytoma cause HTN
Definition
paroxysmal elevation in BP esp with headache, palpations, and sweating
Term
how does primary hyperALD HTN evaluation 2
Definition
hypokelemia due to urinary K wasting
measure plasma ALD to renin ratio to identify
Term
5 signs of cushing syndrome
Definition
moon facies
central obesity
proximal muscle weakness
buffalo hump
striae
Term
how can coarctation of aorta be identified
Definition
diminished or delayed femoral pulse
HTN of upper extremities
low BP in LE
Term
sleep apnea: who normally gets, why, signs 4, risks 2
Definition
obese men
passive collapse of pharyngeal muscle in inspiration

headache, daytime fatigue, depression, snoring

HTN, arrhythmia
Term
what are the 4 stages of blood pressure
Definition
normal <120/80
preHTN 120/80 - 139/89
stage 1 140-90 - 159/99
stage 2 >160/100
Term
tx options for stage 1 HTN 6
Definition
thiaide diruetic
ACE I
ARB
B blocker
CCB
combo
Term
tx options for stage 2 HTN 6
Definition
use two drugs!
thiazide diruetic
ACEI
ARB
B blocker
CCB
Term
symptoms of HTN 7
Definition
in isolation is asymptomatic
headache
fatigue
dizzy
blurred vision
facial flushing
tinnitus
Term
who should get checked for HTN
Definition
every office visit in pt >21yo
Term
what are the parts to a HTN office visit 14
Definition
assess lifestyle
identify risk factors
reveal cause of HTN
assess absence of target organ damage and CV damage
measure BP with verification in other arm
examine fundi
BMT
ascultation of carotid
ascultation of abdomen
ascultation of femoral bruis
palpate thyroid
abdomen exam for kidney and masses
palpate LE for edema and pulses
neurological exam
Term
labs you should get in a HTN exam 8
Definition
creatnin
Na
K
glucose
cholesterol
urine
EKG
CXR
Term
why do you get CXR in HTN exam
Definition
signs of cardiac enlargement or evidence of heart failure
Term
why do you get urine in HTN exam
Definition
proteinuremia can identify kidney cause of HTN or HTN caused kidney damage
Term
why do you get CR in HTN exam 3
Definition
identify renal cause of HTN or HTN caused kidney damage

baseline for latern monitoring of disease

check effects of anti-HTN medications (often renal SE)
Term
what are the follou up recommendations for 6 levels of BP in HTn
Definition
<130/85 recheck in 2y
130/85-139/89 recheck in 1y
140/90 - 159/99 confirm in 2mo
160/100 - 170/109 evaluate in 1mo
180/110 - 109/119 evaluate in 1wk
>210/120 tx immediatly
Term
once you initiate anti-HTN drugs what is the follow up procedure
Definition
retrn to adjust med smonthly until BP goal reached

comorbid conditions or stage 2: return more than monthly

measure serum K and CR 1-2x/y
Term
what is the severity of complications of HTN determined by
Definition
proportional to BP
Term
complications of HTN 7
Definition
short term: HTN emergency
cerebravascular accident: CVA, stroke
MI: heart attack
hypertrophic cardiomyopathy
HTN retinopathy: damage to retina
HTN nephropathy: chronic reinal failure due to high BP
Term
why is hypertrophic cardiomyopathy a result of HTN
Definition
heart failure due to chronic high BP causes LV hypertrophy
Term
below what level of BP are CV complaints reduced
Definition
<140/90
Term
what is inc recommendation 8
Definition
>18yo with chronic kidney disease tx with ACEI/ARB to improve kidney outcomes regardless or race or DM
Term
what is JNC recommendation 1
Definition
general population >60 yo initiate drugs to lower BP when >150/90 with a goal of <150/90

strong recommendation: grade A

if tx lowers it <140 then you dont need to back off on the BP meds. if what it is doing is working dont change it
expert opinion grade E
Term
what is the BP goal in someone with HTN and recent stroke
Definition
only initiate meds if BP >220/110 because the body is using pressure to improve flow to infarct
Term
what is the jNC recommendation 2
Definition
general population <60yo initiate drugs when diastolic > 90 and treat until <90
Term
what is jnc recommendation 3
Definition
<60yo treat when systolic >140 and treat to get less than 140
Term
what is jnc recommendation 7
Definition
AA with DM or wo DM initial therapy choose one
thiazide diruetic and CCB
Term
what is jnc recommendation 4
Definition
>18yo with chronic kidney disease start meds when >140/90 and treat until under that
Term
what is jnc recommendation 5
Definition
>18yo with DM use drugs when >140/90 and treat until under that
Term
what is jnc recommendation 6
Definition
non AA initial therapy should include one...
thiazide, CCB, ACEI, or ARB
Term
what is jnc recommendation 9
Definition
main objective of HTN tx is to maintain a goal BP if it is not reached within 1 mo increase initial drug or add a second drug from list of recommendation for that patient

assess BP and adjust until you achieve goal. if not controlled add 3rd drug

never use ACEI/ARB together. that can worsen hyperkalemia and renal function

if cannot be achieve by 3 drugs or due to contraindications in pt to drugs then other clases can e used (nitrates, hydrolazine)

refer to a HTN specailist
Term
what are the non-pharmacological tx for HTN 8
Definition
diet
avoid alcohol
weight loss
low Na diet
aerobic exercise
stop smoking
relieve stress
sleep more
Term
what amt of drinking is associated with HTN
Definition
>2 drinks a day have 1.5x increase
Term
what is the associatio of weight loss with htn
Definition
lowers BP 0.5-2mmHg/1kg weight lost
Term
what is the benifit of a low Na diet, what does low Na mean
Definition
lower BP
prevent HTN onset
100mew/d (6g sald, 100 mew/d)
Term
what are the goals of HTN tx
Definition
reduce CV morbidity and mortality
achieve systolic goal, diastolic will usually follow
Term
what is the benifit of exercise in someone with HTN
Definition
decrease systolic BP
Term
how is smoking associated with HTN
Definition
smoking dosent cause HTN but causes transient vasoconstrictive effect and increase CV risk in HTN
Term
what is the biggest non-pharmalogical bang for buck in reducing BP
Definition
weight loss
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